Genotoxic and mutational potential of monocyclic terpenoids (carvacrol, carvone and thymol) in Drosophila melanogaster
Toxicology Reports,
Journal Year:
2023,
Volume and Issue:
10, P. 327 - 333
Published: Jan. 1, 2023
Genotoxicity
and
mutagenicity
of
monoterpene
carvone
along
with
the
related
alcohols
–
carvacrol
thymol
have
been
studied
using
Drosophila
melanogaster
as
model
system.
The
viability,
pre-imaginal
stage
duration,
level
dominant
lethal
mutations,
unequal
crossover
in
Bar
mutant
D.
influence
monocyclic
terpenoids
on
multiplication
nuclear
genome
salivary
gland
cells
were
investigated.
compounds
tested
after
oral
administration
(0.02%
1,2-propylene
glycol)
degree
chromosome
polyteny
larvae.
Among
examined,
exhibited
most
significant
impact
imago
lifespan,
frequency
when
added
to
culture
medium.
Oral
increases
average
highest
value
for
1178
C
compared
control
(776
C).
conceivable
mechanism
action
associated
juvenile
hormone
activity
is
debated.
Language: Английский
Seasonal variation in endoreduplication and polyteny in the fruit fly Drosophila melanogaster (Diptera: Drosophilidae): How does it contribute to adaptation?
European Journal of Entomology,
Journal Year:
2025,
Volume and Issue:
122, P. 1 - 10
Published: Jan. 28, 2025
Language: Английский