Melatonin Alleviates T-2 Toxin-Induced Intestinal Injury by Enhancing Gut Barrier Function and Modulating Microbiota in Weaned Piglets DOI
You Wu,

Wenguang Xiao,

Bo Xiao

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

The T-2 toxin, originating from a Fusarium species, is mycotoxin that can adversely affect animal health. Melatonin (MT) natural hormone recognized for its properties reduce inflammation and act as an antioxidant. However, MT's capacity to alleviate intestinal harm toxin remains incompletely explored. Employing postweaning piglets, this research investigates prophylactic impact on toxin-induced enterotoxicity. results indicate MT improved growth performance in piglets exposed toxins while also enhancing barrier function. Such effects probably stem ability colonic oxidative stress inflammation. Further findings suggest these changes are closely associated with MT-induced remodeling of microbiota increase short-chain fatty acid (SCFA) levels the intestine. therefore alleviates damage; gut key process.

Language: Английский

Melatonin Alleviates T-2 Toxin-Induced Intestinal Injury by Enhancing Gut Barrier Function and Modulating Microbiota in Weaned Piglets DOI
You Wu,

Wenguang Xiao,

Bo Xiao

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

The T-2 toxin, originating from a Fusarium species, is mycotoxin that can adversely affect animal health. Melatonin (MT) natural hormone recognized for its properties reduce inflammation and act as an antioxidant. However, MT's capacity to alleviate intestinal harm toxin remains incompletely explored. Employing postweaning piglets, this research investigates prophylactic impact on toxin-induced enterotoxicity. results indicate MT improved growth performance in piglets exposed toxins while also enhancing barrier function. Such effects probably stem ability colonic oxidative stress inflammation. Further findings suggest these changes are closely associated with MT-induced remodeling of microbiota increase short-chain fatty acid (SCFA) levels the intestine. therefore alleviates damage; gut key process.

Language: Английский

Citations

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