Energy Expenditure in Critically Ill Patients with Aneurysmal Subarachnoid Hemorrhage, Intracerebral Hemorrhage, and Traumatic Brain Injury—A Prospective Observational Study DOI Open Access

Geraldine de Heer,

A. Doliwa,

Pascal Hilbert

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(20), P. 3448 - 3448

Published: Oct. 11, 2024

Background: Energy expenditure (EE) in patients with aneurysmal subarachnoid hemorrhage (SAH) may differ from other intracranial pathologies, such as intracerebral (ICH) or traumatic brain injury (TBI), due to an activation of the sympathetic nervous system. Indirect calorimetry (IC) is recommended, but not always available. We study EE, catabolism, and metabolic stress SAH, TBI, ICH, sepsis controls. Methods: A prospective observational was conducted intensive care units University Medical Center Hamburg-Eppendorf, Germany. IC used measure EE on days 2–3, 5–7, 10–15 post-admission. Urinary catecholamines, metabolites, urine urea were also measured. Statistical analysis included t-tests, Chi-square tests, generalized mixed models. Results: 110 patients—43 SAH (13 surgical securing aneurysm 30 coil embolization aneurysm), 22 TBI patients, 23 ICH The linear model for groups timepoints including age, height, weight covariates revealed a significantly lower at timepoint 1 versus SAH—interventional (p = 0.003) control 0.004), well 2 0.002) SAH—surgical 0.013) patients. No significant differences between found timepoints, concerning measurements catecholamines urine. Conclusions: In no meaningful detected compared septic critically ill except early phase.

Language: Английский

Energy Expenditure in Critically Ill Patients with Aneurysmal Subarachnoid Hemorrhage, Intracerebral Hemorrhage, and Traumatic Brain Injury—A Prospective Observational Study DOI Open Access

Geraldine de Heer,

A. Doliwa,

Pascal Hilbert

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(20), P. 3448 - 3448

Published: Oct. 11, 2024

Background: Energy expenditure (EE) in patients with aneurysmal subarachnoid hemorrhage (SAH) may differ from other intracranial pathologies, such as intracerebral (ICH) or traumatic brain injury (TBI), due to an activation of the sympathetic nervous system. Indirect calorimetry (IC) is recommended, but not always available. We study EE, catabolism, and metabolic stress SAH, TBI, ICH, sepsis controls. Methods: A prospective observational was conducted intensive care units University Medical Center Hamburg-Eppendorf, Germany. IC used measure EE on days 2–3, 5–7, 10–15 post-admission. Urinary catecholamines, metabolites, urine urea were also measured. Statistical analysis included t-tests, Chi-square tests, generalized mixed models. Results: 110 patients—43 SAH (13 surgical securing aneurysm 30 coil embolization aneurysm), 22 TBI patients, 23 ICH The linear model for groups timepoints including age, height, weight covariates revealed a significantly lower at timepoint 1 versus SAH—interventional (p = 0.003) control 0.004), well 2 0.002) SAH—surgical 0.013) patients. No significant differences between found timepoints, concerning measurements catecholamines urine. Conclusions: In no meaningful detected compared septic critically ill except early phase.

Language: Английский

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