The Effect of Hemoadsorption with CytoSorb on Severe COVID-19 Complications DOI Creative Commons
A. S. Rybalko, S. N. Galkina,

A. S. Saryglar

et al.

General Reanimatology, Journal Year: 2024, Volume and Issue: 20(4), P. 30 - 38

Published: Sept. 6, 2024

The aim of the study was to assess effect hemoadsorption with CytoSorb on inflammatory response, respiratory failure, and mortality in patients severe novel coronavirus infection. Materials methods. A retrospective single-center cohort comparative hemoadsorbtion using therapy included data from 124 COVID-19 ICU patients. Patients were divided into two groups: arm (group 1, N =93) control without 2, =31). group 1 had more failure at baseline, but otherwise comparable 2 terms clinical demographic parameters. R esults. After hemoadsorption, showed significant improvement 9 13 monitored clinical, instrumental, laboratory parameters: fever (P=0.005), lactate dehydrogenase (LDH) ( P <0.001), C-reactive protein (CRP) IL-6 <0.001) levels, as well an increase SpO₂/FiO₂ ratio =0.041), leukocyte count lymphocyte =0.003), no changes SOFA score =0.068). only seen a reduction =0.003). Other unfavorable, such decrease =0.002), inspiratory oxygen fraction FiO₂ =0.001), <0.05), LDH =0.038), procalcitonin =0.005), 3.0 7.0 (95%CI, 3.0–9.0) =0.001). all-cause hospital rate 37,63% 74.20% 2. C onclusion. use pathogenetic targeting hyperinflammatory response management algorithm complications resulted resolution mortality.

Language: Английский

Nano bioceramics: Properties, applications, hydroxyapatite, nanohydroxyapatite and drug delivery DOI Creative Commons
Ahmed Mahdi Rheima,

Ali Assim Abdul-Rasool,

Zainab T. Al‐Sharify

et al.

Case Studies in Chemical and Environmental Engineering, Journal Year: 2024, Volume and Issue: 10, P. 100869 - 100869

Published: July 29, 2024

Bone is the second organ of human body that has most transplants. The concept bone repair evolved over past five decades and known as third generation biomaterials. During integration nanotechnology with bioceramics, an emerging research field called nanobioceramics been born within Due to chemical similarity mineral content bone, are included in definition a new biomaterials whose main purpose create microenvironment improve cellular responses leading osteogenesis. Hydroxyapatite member calcium phosphate family. This substance, which bioactive biocompatible compound, considered component tissue. structural this compound it widely used tissue dental orthopedic applications. Many basic properties hydroxyapatite can be improved by changing scale its particles nanoparticles. Therefore, recent years, various methods for synthesis nanohydroxyapatite have reported. Using different characterization methods, quality synthesized nanostructures checked. In addition bone-related fields, also carrier transfer materials, including drugs, vitamins, proteins. article, modern times, advances biomedical focusing on use bioceramics treatment diseases, function vital organs, engineering brought hopes regenerative medicine. Various being investigated synthesize bioceramic materials using natural synthetic materials. There several challenges enable cost-effective material minimize rejection biological systems. One major incorporating foreign into systems their acceptance reduce humans other organisms studying immune responses. When developing ceramic mechanical one important parameters humans. evaluation criteria mechanical, existing approaches play crucial role validating bioceramics. State-of-the-art techniques

Language: Английский

Citations

16
Effect and investigating of oxygen / nitrogen on modified glassy carbon electrode chitosan/carbon nanotube and best detection of nicotine using Cyclic voltammetry measurement technique DOI Creative Commons
Abolfazl Mirani, Ahmed Mahdi Rheima,

Zainab talib turki

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 10, P. 101739 - 101739

Published: Aug. 1, 2024

Language: Английский

Citations

5
Biosurfactants: Properties, Applications and Emerging Trends DOI Creative Commons
Chou‐Yi Hsu,

Zaid H. Mahmoud,

Uday Abdul‐Reda Hussein

et al.

South African Journal of Chemical Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Development of Vitex-derived polymer nanofibers using electrochemical sensors for the treatment of polycystic ovarian syndrome in rats as an animal model DOI Creative Commons

Zaid H. Mahmoud,

Uday Abdul‐Reda Hussein,

Najwa Aljbory

et al.

Biosensors and Bioelectronics X, Journal Year: 2024, Volume and Issue: unknown, P. 100570 - 100570

Published: Dec. 1, 2024

Language: Английский

Citations

2
The Effect of Hemoadsorption with CytoSorb on Severe COVID-19 Complications DOI Creative Commons
A. S. Rybalko, S. N. Galkina,

A. S. Saryglar

et al.

General Reanimatology, Journal Year: 2024, Volume and Issue: 20(4), P. 30 - 38

Published: Sept. 6, 2024

The aim of the study was to assess effect hemoadsorption with CytoSorb on inflammatory response, respiratory failure, and mortality in patients severe novel coronavirus infection. Materials methods. A retrospective single-center cohort comparative hemoadsorbtion using therapy included data from 124 COVID-19 ICU patients. Patients were divided into two groups: arm (group 1, N =93) control without 2, =31). group 1 had more failure at baseline, but otherwise comparable 2 terms clinical demographic parameters. R esults. After hemoadsorption, showed significant improvement 9 13 monitored clinical, instrumental, laboratory parameters: fever (P=0.005), lactate dehydrogenase (LDH) ( P <0.001), C-reactive protein (CRP) IL-6 <0.001) levels, as well an increase SpO₂/FiO₂ ratio =0.041), leukocyte count lymphocyte =0.003), no changes SOFA score =0.068). only seen a reduction =0.003). Other unfavorable, such decrease =0.002), inspiratory oxygen fraction FiO₂ =0.001), <0.05), LDH =0.038), procalcitonin =0.005), 3.0 7.0 (95%CI, 3.0–9.0) =0.001). all-cause hospital rate 37,63% 74.20% 2. C onclusion. use pathogenetic targeting hyperinflammatory response management algorithm complications resulted resolution mortality.

Language: Английский

Citations

0