Frontiers in nanoparticles redefining enzyme immobilization: a review addressing challenges, innovations, and unlocking sustainable future potentials

Micro and Nano Systems Letters, Journal Year: 2025, Volume and Issue: 13(1)

Published: May 12, 2025

Abstract Nanoparticles (NPs) are redefining enzyme immobilization, offering a paradigm shift in biocatalysis through precision engineering at the nanoscale. With their exceptional surface area, tunable porosity, and customizable functionalities, NPs provide unprecedented control over stability, activity, adaptability, bridging gap between molecular-scale interactions industrial-scale applications. In era of intelligent bioprocessing, how can NP-based immobilization strategies be optimized to drive next frontier sustainable high-performance technologies? A deep understanding NP structural diversity, interfacial chemistry, enzyme-matrix is crucial unlocking full potential. This review systematically explores emerging platforms, including cross-linked aggregates (CLEAs), covalent organic frameworks (COFs), nanoflowers, nanofibers, carbon nanotubes (CNTs), graphene oxide (GO), ionic liquids (ILs), layered double hydroxides (LDHs), each tailored advantages for catalytic enhancement process efficiency. The outlines current advancements such as 3D printing wearable biosensors, forecasts integration artificial intelligence smart nano-biocatalysts, envisions futuristic applications bio-intelligent nano/micro-robotic systems space biosensors. Challenges, upscaling limitations, nanotoxicity concerns, environmental risks, addressed ensure safe viable implementation. provides structured roadmap on (I) advances using next-generation NPs, (II) challenges scalability safety, (III) sustainability benefits enzyme-based industrial biocatalysis, (IV) emergence intelligence, nanoscale technologies AI-assisted design optimization. These visionary approaches mark toward dynamic, adaptive, highly specialized, multifunctional nano-enzyme systems. Graphical

Language: Английский

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Novel Aryl Hydrocarbon Receptor Agonist Compounds for Treating Psoriasis and Atopic Dermatitis

ACS Medicinal Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown

Published: May 16, 2025

Language: Английский

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