Isolation, Characterization, and Biomedical Potential of Phycoerythrin Phycobiliprotein from Kappaphycus alvarezii (Doty) Doty ex Silva: Antimicrobial, Antioxidant, and Anticancer Activities

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

Kappaphycus alvarezii (Doty) Doty ex Silva, a red seaweed widely cultivated for carrageenan polysaccharide, is also potential source of the valuable pigment phycoerythrin (PE). Therefore, this study aims to extract from K. alvarezii, evaluate its antimicrobial, antioxidant, and anticancer activities, identify biomedical future therapeutic applications. The protein content extracted was found be 69.84% showed excellent antimicrobial activity against Klebsiella oxytoca Proteus mirabilis, with minimum inhibition zone 11 mm. It significant in vitro antioxidant activity, as analyzed using total hydrogen peroxide scavenging, reducing power, DPPH, ABTS assays. Further, exhibited potent cytotoxicity human lung cancer cell line, an IC₅₀ value 131.7 µg mL^-1. Furthermore, increasing concentration decreased proliferation induced apoptosis, confirmed by Annexin V/PI staining. Comprehensive characterization FT-IR, HPLC, GC-MS analysis revealed nature functional groups, highlighting molecular docking alvarezii-derived compounds binding affinities 13 antibacterial target proteins. These results highlight bioactive promising agents. demonstrated properties, cells apoptosis induction. Structural composition, emphasizing natural agent. findings support application in pharmaceutical industry.

Language: Английский

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Current Status of Eucheumatoid Seaweed Farming in Tawi-Tawi, Philippines

Published: Jan. 1, 2025

Language: Английский

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Growth rate comparison of three Kappaphycus alvarezii colour strains cultivated using tubular netting and tie-tie methods in the waters of Ecuador

Journal of Applied Phycology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Language: Английский

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Liquid extract of Kappaphycus alvarezii enhances growth and metabolic responses in in vitro cultivated explants of this same species

Journal of Applied Phycology, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

Language: Английский

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Efficacy of seaweed extracts on the germination of commercially important crops Triticum aestivum (wheat) and Vigna radiata (mung bean)

Journal of Applied Phycology, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Language: Английский

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Marine and terrestrial biostimulant elicitors of tolerance to cold stress

Frontiers in Plant Science, Journal Year: 2025, Volume and Issue: 16

Published: April 8, 2025

The increasing frequency of adverse environmental events, driven by ongoing climate change, has intensified the search for new technological alternatives in crop production and plant protection. Thermal stress can limit adaptation negatively impact metabolism, physiology, morphology, yield. Cold plants been extensively studied affect various stages plant's life cycle, from seed formation to development, causing damage cell membranes, impairing division, disrupting water absorption. Consequently, researchers have focused on mitigating impacts abiotic investigating bioactive molecules biostimulants derived organisms, which enhance tolerance mechanisms plants. In aquatic environments, macro- microalgae emerged as key sources elicitors, providing extractable such polysaccharides, polyamines, polyphenols, amino acids that defense responses. Similarly, certain terrestrial shown potential biostimulant compounds. Thus, this study aims highlight advancements systems emphasizing algae-based elicitors enhancing cold stress. Ultimately, goal is improve understanding promising biological models food production, fostering innovative developments contribute economically ecologically sustainable technologies.

Language: Английский

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Therapeutic Prospects of Undaria pinnatifida Polysaccharides: Extraction, Purification, and Functional Activity

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(4), P. 163 - 163

Published: April 8, 2025

Undaria pinnatifida, an edible brown seaweed that is widely consumed in East Asia, has gained increasing recognition for its health benefits. Among bioactive compounds, polysaccharides have attracted significant attention due to their diverse biological activity. This review provides a comprehensive overview of recent advancements the extraction, purification, structural characterization, and bioactivity U. pinnatifida polysaccharides. We discuss state-of-the-art extraction techniques, including ultrasound-assisted, microwave-assisted, enzyme-assisted as well purification strategies such membrane separation chromatographic methods. Furthermore, we highlight potential activity, antioxidant, immunomodulatory, anticancer, gut health-promoting, anti-hyperglycemic effects, along with underlying mechanisms action. By summarizing latest research, this aims provide valuable insights into development application functional foods pharmaceuticals.

Language: Английский

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A Biostimulant from Kappaphycus alvarezii Enhances the Growth and Development of Basil (Ocimum basilicum L.) Plants

Horticulturae, Journal Year: 2025, Volume and Issue: 11(4), P. 424 - 424

Published: April 16, 2025

This study evaluated the efficacy and optimal concentrations of Kappaphycus alvarezii biostimulant from São Paulo (Kal-SP) Santa Catarina (Kal-SC) for hydroponic cultivation basil (Ocimum basilicum). Basil plants were grown with 1%, 3%, 5%, 7% each extract using distilled water as a control. The extracts applied via weekly foliar sprays. Morphological biochemical parameters, in addition to biogenic amine profile, evaluated. Morphologically, 3% Kal-SP increased plant height by 17.1% length roots 54.8%, while 5% Kal-SC enhanced node number 95.2% 120.2%, respectively. Biochemically, 1% maximized chlorophyll carotenoid content, 5–7% soluble sugars, 3–7% elevated starch. Amino acid levels highest Kal-SC. profile was also modulated K. extracts, demonstrating their ability influence compounds interest. results suggest that or higher these can be beneficially cultivation, potential variations depending on seaweed’s geographic origin.

Language: Английский

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Technical efficiency of Kappaphycus alvarezii farming in Wagina, Choiseul Province (the Solomon Islands)

Aquaculture International, Journal Year: 2025, Volume and Issue: 33(4)

Published: April 24, 2025

Language: Английский

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Effect of Biomass Drying Protocols on Bioactive Compounds and Antioxidant and Enzymatic Activities of Red Macroalga Kappaphycus alvarezii

Methods and Protocols, Journal Year: 2024, Volume and Issue: 7(6), P. 88 - 88

Published: Nov. 1, 2024

is a red seaweed used globally in various biotechnological processes. To ensure the content and stability of its bioactive compounds postharvest, suitable drying protocols must be adopted to provide high-quality raw materials for industrial use. This study aimed analyze influence freeze-drying oven-drying on total phenolic (TPC), flavonoid (TFC), antioxidant activity (FRAP DPPH assays), carotenoid (TC), lipase (LA) protease (PA)

Language: Английский

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