Green synthesis of Ag/V2O5 and Ag/V2O5-curdlan nanocomposites from Sargassum latifolium extract for enhanced antimicrobial and antioxidant activities

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 301, P. 140472 - 140472

Published: Jan. 30, 2025

Language: Английский

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Sorghum Grain-Derived Kafirin Nanoparticles For Effective Delivery of Corosolic Acid into Breast Cancer Cells for Potential Treatment of Breast Cancer

Journal of Cluster Science, Journal Year: 2025, Volume and Issue: 36(3)

Published: April 4, 2025

Language: Английский

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β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Abstract Innate immune cells such as macrophages and dendritic play major roles in the progression of many cancerous, fibrotic, autoimmune diseases, often due to environmental cues that skew these toward a phenotype progresses or exacerbates disease state. As such, growing focus treating diseases is placed on exploiting high plasticity modify reverse their pro‐disease phenotypes using immunomodulatory materials. β‐1,3 glucans are one type material has exhibited diverse effects cells, including mitigation reversal adverse dysregulated cells. In this review, we outline various fabrication techniques produce glucan‐derived microparticles nanoparticles discuss particle properties can be obtained by tuning glucan chemistry, method, formulation components. Furthermore, applications particles highlighted with cell targeting, modulation, delivery small molecule macromolecular therapeutics.

Language: Английский

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Effects of Different Plasticizers on the Structure, Physical Properties and Film Forming Performance of Curdlan Edible Films

Foods, Journal Year: 2024, Volume and Issue: 13(23), P. 3930 - 3930

Published: Dec. 5, 2024

This study successfully developed edible films with excellent mechanical strength and notable water resistance, utilizing curdlan (CL) as the primary matrix incorporating various plasticizers, including glycerol (GLY), ethylene glycol (EG), propylene (PRO), xylitol (XY), sorbitol (SOR), polyethylene (PEG). A comprehensive suite of analytical techniques, Fourier transform infrared spectroscopy (FTIR), wide-angle X-ray diffraction (XRD), scanning electron microscopy (SEM), dynamic analysis (DMA), tensile testing, were employed to evaluate films' structural properties. After PEG, sensitivity increased slightly, a contact angle (CA) 97.6°, solubility (WS) 18.75%. The inclusion plasticizers altered crystalline structure CL matrix, smoothing flattening film surface while reducing hydrogen-bonding interactions. These changes led more uniform distribution amorphous chain segments decrease in glass transition temperatures. Among tested GLY exhibited highest compatibility CL, resulting smoothest morphology delivering most effective plasticizing effect. CL-GLY showed dramatic improvement flexibility, an elongation at break that was 5.2 times higher than unplasticized (increasing from 5.39% 33.14%), indicating significant enhancement extensibility. Overall, these findings highlight potential sustainable materials for food packaging applications.

Language: Английский

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Fabrication of folic acid-conjugated pyrimidine-2(5H)-thione-encapsulated curdlan gum-PEGamine nanoparticles for folate receptor targeting breast cancer cells

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134406 - 134406

Published: Aug. 3, 2024

Language: Английский

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Pharmacokinetics and Brain Tumor Delivery Studies of Thymoquinone-Encapsulated Eudragit L100-Coated Solid-Lipid Nanoparticles

Journal of Cluster Science, Journal Year: 2024, Volume and Issue: 36(1)

Published: Dec. 19, 2024

Language: Английский

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