Synthesis of Rh-MOF/PVA-PVP nanofibers for skin cancer and infection inhibition DOI Creative Commons

Ali Altharawi,

Taibah Aldakhil,

Manal A. Alossaimi

et al.

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: April 28, 2025

Using electrospinning for nanofiber production, we can create unique materials with multiple applications in various industries, including medical bandages and wound dressings. One of the most important features these using technique, is incorporation compounds metals into their structure. In this study, a new metal-organic framework (MOF) was synthesized from rhodium, metal significant biological potential, which then used to produce nanofibers (Rh-MOF/PVA-PVP nanofiber) by mixing polyvinyl alcohol (PVA) polyvinylpyrrolidone (PVP). The newly tested against common microbial skin pathogens cancer cells, showing inhibition. Specifically, an IC 50 value 19.45 μg/mL cells MIC values ranging 4 64 μg pathogenic strains were observed. This notable inhibitory ability be attributed both physical characteristics (with specific surface area 2,348 m 2 /g), chemical factors, active present its rhodium (Rh) Rh-MOF/PVA-PVP has potential use developing bioactive bandages,

Language: Английский

Synthesis of Rh-MOF/PVA-PVP nanofibers for skin cancer and infection inhibition DOI Creative Commons

Ali Altharawi,

Taibah Aldakhil,

Manal A. Alossaimi

et al.

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: April 28, 2025

Using electrospinning for nanofiber production, we can create unique materials with multiple applications in various industries, including medical bandages and wound dressings. One of the most important features these using technique, is incorporation compounds metals into their structure. In this study, a new metal-organic framework (MOF) was synthesized from rhodium, metal significant biological potential, which then used to produce nanofibers (Rh-MOF/PVA-PVP nanofiber) by mixing polyvinyl alcohol (PVA) polyvinylpyrrolidone (PVP). The newly tested against common microbial skin pathogens cancer cells, showing inhibition. Specifically, an IC 50 value 19.45 μg/mL cells MIC values ranging 4 64 μg pathogenic strains were observed. This notable inhibitory ability be attributed both physical characteristics (with specific surface area 2,348 m 2 /g), chemical factors, active present its rhodium (Rh) Rh-MOF/PVA-PVP has potential use developing bioactive bandages,

Language: Английский

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