Cited by Higher dietary inflammatory index linked to increased risk of hypertension: a systematic review and dose-response meta-analysis

Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay DOI

Hadi Mansour,

Hasan Slika, Suzanne A. Nasser

et al.

Pharmacological Research, Journal Year: 2024, Volume and Issue: 209, P. 107452 - 107452

Published: Oct. 8, 2024

Language: Английский

Citations

Revisiting high-density lipoprotein cholesterol in cardiovascular disease: Is too much of a good thing always a good thing? DOI

Mohammad Al Zein,

Alicia Khazzeka, Alessandro El Khoury

et al.

Progress in Cardiovascular Diseases, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

Latest evidence on assessment and invasive management of non-st-segment elevation acute coronary syndrome (NSTE-ACS) in the older population DOI

Kieran Gill,

Gregory Mills, Wanqi Wang

et al.

Expert Review of Cardiovascular Therapy, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Introduction Invasive management of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) should be considered regardless age, but a key challenge is deciding which patients are most likely to benefit from an invasive approach in the older population. In addition assessment clinical signs and symptoms, holistic geriatric syndromes such as frailty, multimorbidity cognitive impairment increasing importance. Recent trials have validated roles physiological intracoronary imaging guide revascularisation.

Language: Английский

Citations

Epigenetics is involved in the pleiotropic effects of statins DOI

Cezar Kayzuka Cotta Filho,

Vitória Carolina Rondon-Pereira,

C. Tavares

et al.

Expert Opinion on Drug Metabolism & Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Statins have significantly reduced mortality from cardiovascular diseases by lowering serum cholesterol levels. Beyond their lipid-lowering effects, statins improve vascular function, reduce inflammation, decrease reactive oxygen species (ROS) formation, and stabilize atherosclerotic plaques. However, the mechanisms underlying these pleiotropic effects remain unclear. This narrative review summarizes discusses epigenetic that may explain part of statins. approach allows for a reevaluation statin use beyond its cholesterol-lowering benefits. A structured search was conducted in PubMed Scopus databases using specific terms, including articles published up to August 2024. The statins, those mediated isoprenoid pathway, partially clinical By inhibiting histone deacetylases (HDACs, "erasers") DNA methyltransferases (DNMTs, "writers"), promote increased acetylation methylation at gene promoter regions. These modifications enhance chromatin accessibility, facilitating transcription protecting system. Further investigation into could support repositioning broader therapeutic applications. extend role managing hypercholesterolemia, potentially becoming first-line treatment preventing disease-related mortality.

Language: Английский

Citations

The Regulatory Role of NcRNAs in Pyroptosis and Disease Pathogenesis DOI

Shaocong Wang,

Xinzhe Chen, Kun Wang

et al.

Cell Biochemistry and Biophysics, Journal Year: 2025, Volume and Issue: unknown

Published: April 18, 2025

Language: Английский

Citations

Exploring the role of exosomes in the pathogenesis and treatment of cardiomyopathies: A comprehensive literature review DOI

Shadiya FawzuAmeer,

Manar Elsaka,

Summaiya Kahtoon

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: 357, P. 123063 - 123063

Published: Sept. 17, 2024

Language: Английский

Citations

Higher dietary inflammatory index linked to increased risk of hypertension: a systematic review and dose-response meta-analysis DOI

Xiaoru Song,

Kun Yang, Cheng Cheng

et al.

European Journal of Clinical Nutrition, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 24, 2024

Language: Английский

Citations