PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(11), P. e0311370 - e0311370
Published: Nov. 27, 2024
The
increasing
availability
of
massive
genetic
sequencing
data
in
the
clinical
setting
has
triggered
need
for
appropriate
tools
to
help
fully
exploit
wealth
information
these
possess.
GFPrint™
is
a
proprietary
streaming
algorithm
designed
meet
that
need.
By
extracting
most
relevant
functional
features,
transforms
high-dimensional,
noisy
into
an
embedded
representation,
allowing
unsupervised
models
create
clusters
can
be
re-mapped
original
information.
Ultimately,
this
allows
identification
genes
and
pathways
disease
onset
progression.
been
tested
validated
using
two
cancer
genomic
datasets
publicly
available.
Analysis
TCGA
dataset
identified
panels
whose
mutations
appear
negatively
influence
survival
non-metastatic
colorectal
(15
genes),
epidermoid
non-small
cell
lung
(167
genes)
pheochromocytoma
(313
patients.
Likewise,
analysis
Broad
Institute
75
involved
related
extracellular
matrix
reorganization
dictate
worse
prognosis
breast
accessible
through
secure
web
portal
used
any
therapeutic
area
where
profile
patients
influences
evolution.
Sensors,
Journal Year:
2024,
Volume and Issue:
24(8), P. 2383 - 2383
Published: April 9, 2024
Classification-based
myoelectric
control
has
attracted
significant
interest
in
recent
years,
leading
to
prosthetic
hands
with
advanced
functionality,
such
as
multi-grip
hands.
Thus
far,
high
classification
accuracies
have
been
achieved
by
increasing
the
number
of
surface
electromyography
(sEMG)
electrodes
or
adding
other
sensing
mechanisms.
While
many
prescribed
still
adopt
two-electrode
sEMG
systems,
detailed
studies
on
signal
processing
and
performance
are
lacking.
In
this
study,
nine
able-bodied
participants
were
recruited
perform
six
typical
hand
actions,
from
which
signals
two
acquired
using
a
Delsys
Trigno
Research+
acquisition
system.
Signal
machine
learning
algorithms,
specifically,
linear
discriminant
analysis
(LDA),
k-nearest
neighbors
(KNN),
support
vector
machines
(SVM),
used
study
accuracies.
Overall
accuracy
93
±
2%,
action-specific
97
F1-score
87
7%
achieved,
comparable
those
reported
multi-electrode
systems.
The
highest
SVM
algorithm
compared
LDA
KNN
algorithms.
A
logarithmic
relationship
between
features
was
revealed,
plateaued
at
five
features.
These
comprehensive
findings
may
potentially
contribute
strategies
for
commonly
systems
further
improve
functionality.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: July 17, 2024
Abstract
The
microarray
gene
expression
data
poses
a
tremendous
challenge
due
to
their
curse
of
dimensionality
problem.
sheer
volume
features
far
surpasses
available
samples,
leading
overfitting
and
reduced
classification
accuracy.
Thus
the
must
be
with
efficient
feature
extraction
methods
reduce
extract
meaningful
information
enhance
accuracy
interpretability.
In
this
research,
we
discover
uniqueness
applying
STFT
(Short
Term
Fourier
Transform),
LASSO
(Least
Absolute
Shrinkage
Selection
Operator),
EHO
(Elephant
Herding
Optimisation)
for
extracting
significant
from
lung
cancer
reducing
database.
is
performed
using
following
classifiers:
Gaussian
Mixture
Model
(GMM),
Particle
Swarm
Optimization
(PSO)
GMM,
Detrended
Fluctuation
Analysis
(DFA),
Naive
Bayes
classifier
(NBC),
Firefly
Support
Vector
Machine
Radial
Basis
Kernel
(SVM-RBF)
Flower
Pollination
(FPO)
GMM.
FPO-GMM
attained
highest
in
range
96.77,
an
F1
score
97.5,
MCC
0.92
Kappa
0.92.
reported
results
underline
significance
utilizing
STFT,
LASSO,
data.
These
methodologies
also
help
improved
early
diagnosis
enhanced
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(7), P. e0306987 - e0306987
Published: July 11, 2024
The
laboratory-scale
(
in-vitro
)
microbial
fermentation
based
on
screening
of
process
parameters
(factors)
and
statistical
validation
(responses)
using
regression
analysis.
recent
trends
have
shifted
from
full
factorial
design
towards
more
complex
response
surface
methodology
designs
such
as
Box-Behnken
design,
Central
Composite
design.
Apart
the
optimisation
methodologies,
listed
are
not
flexible
enough
in
deducing
properties
terms
class
variables.
Machine
learning
algorithms
unique
visualisations
for
dataset
presented
with
appropriate
algorithms.
classification
cannot
be
applied
all
datasets
selection
classifier
is
essential
this
regard.
To
resolve
issue,
factor-response
relationship
needs
to
evaluated
subsequent
preprocessing
could
lead
results.
aim
current
study
was
investigate
data-mining
accuracy
developed
pyruvate
production
organic
sources
first
time.
attributes
were
subjected
comparative
various
classifiers
accuracy,
multilayer
perceptron
(neural
network
algorithm)
selected
classifier.
As
per
results,
model
showed
significant
results
prediction
classes
a
good
fit.
curve
also
converging
linearly
separable.
Algorithms,
Journal Year:
2024,
Volume and Issue:
17(8), P. 342 - 342
Published: Aug. 6, 2024
This
study
presents
a
novel
method,
termed
RBAVO-DE
(Relief
Binary
African
Vultures
Optimization
based
on
Differential
Evolution),
aimed
at
addressing
the
Gene
Selection
(GS)
challenge
in
high-dimensional
RNA-Seq
data,
specifically
rnaseqv2
lluminaHiSeq
un
edu
Level
3
RSEM
genes
normalized
dataset,
which
contains
over
20,000
genes.
RNA
Sequencing
(RNA-Seq)
is
transformative
approach
that
enables
comprehensive
quantification
and
characterization
of
gene
expressions,
surpassing
capabilities
micro-array
technologies
by
offering
more
detailed
view
expression
data.
Quantitative
analysis
can
be
pivotal
identifying
differentiate
normal
from
malignant
tissues.
However,
managing
these
dense
matrix
data
significant
challenges.
The
algorithm
designed
to
meticulously
select
most
informative
dataset
comprising
than
assess
their
relevance
across
twenty-two
cancer
datasets.
To
determine
effectiveness
selected
genes,
this
employs
Support
Vector
Machine
(SVM)
k-Nearest
Neighbor
(k-NN)
classifiers.
Compared
binary
versions
widely
recognized
meta-heuristic
algorithms,
demonstrates
superior
performance.
According
Wilcoxon’s
rank-sum
test,
with
5%
significance
level,
achieves
up
100%
classification
accuracy
reduces
feature
size
98%
datasets
examined.
advancement
underscores
potential
enhance
precision
selection
for
research,
thereby
facilitating
accurate
efficient
identification
key
genetic
markers.
Complex & Intelligent Systems,
Journal Year:
2024,
Volume and Issue:
10(6), P. 8355 - 8382
Published: Aug. 28, 2024
Abstract
In
this
paper,
based
on
facial
landmark
approaches,
the
possible
vulnerability
of
ensemble
algorithms
to
FGSM
attack
has
been
assessed
using
three
commonly
used
models:
convolutional
neural
network-based
antialiasing
(A_CNN),
Xc_Deep2-based
DeepLab
v2,
and
SqueezeNet
(Squ_Net)-based
Fire
modules.
Firstly,
individual
deep
learning
classifier-based
Facial
Emotion
Recognition
(FER)
classifications
have
developed;
predictions
from
all
classifiers
are
then
merged
majority
voting
develop
HEM_Net-based
model.
Following
that,
an
in-depth
investigation
their
performance
in
case
attack-free
carried
out
terms
Jaccard
coefficient,
accuracy,
precision,
recall,
F1
score,
specificity.
When
applied
benchmark
datasets,
ensemble-based
method
(HEM_Net)
significantly
outperforms
precision
reliability
while
also
decreasing
dimensionality
input
data,
with
accuracy
99.3%,
87%,
99%
for
Extended
Cohn-Kanade
(CK+),
Real-world
Affective
Face
(RafD),
Japanese
female
expressions
(Jaffee)
respectively.
Further,
a
comprehensive
analysis
drop
every
model
affected
by
is
over
range
epsilon
values
(the
perturbation
parameter).
The
results
experiments
show
that
advised
HEM_Net
declined
drastically
59.72%
CK
+
42.53%
RafD
images,
48.49%
Jaffee
dataset
when
increased
A
E
(attack
levels).
This
demonstrated
successful
Fast
Gradient
Sign
Method
(FGSM)
can
reduce
prediction
increase
levels.
However,
due
voting,
proposed
could
improve
its
robustness
against
attacks,
indicating
lessen
deception
adversarial
instances.
generally
holds
even
as
level
increases.
International Journal of Imaging Systems and Technology,
Journal Year:
2024,
Volume and Issue:
34(5)
Published: Sept. 1, 2024
ABSTRACT
Colorectal
adenocarcinoma,
the
most
prevalent
form
of
colon
cancer,
originates
in
glandular
structures
intestines,
presenting
histopathological
abnormalities
affected
tissues.
Accurate
gland
segmentation
is
crucial
for
identifying
these
potentially
fatal
abnormalities.
While
recent
methodologies
have
shown
success
segmenting
glands
benign
tissues,
their
efficacy
diminishes
when
applied
to
malignant
tissue
segmentation.
This
study
aims
develop
a
robust
learning
algorithm
using
convolutional
neural
network
(CNN)
segment
histology
images.
The
methodology
employs
CNN
based
on
U‐Net
architecture,
augmented
by
weighted
ensemble
that
integrates
DenseNet
169,
Inception
V3,
and
Efficientnet
B3
as
backbone
models.
Additionally,
segmented
boundaries
are
refined
watershed
algorithm.
Evaluation
Warwick‐QU
dataset
demonstrates
promising
results
model,
achieving
an
F1
score
0.928
0.913,
object
dice
coefficient
0.923
0.911,
Hausdorff
distances
38.97
33.76
test
sets
A
B,
respectively.
These
compared
with
outcomes
from
GlaS
challenge
(MICCAI
2015)
existing
research
findings.
Furthermore,
our
model
validated
publicly
available
named
LC25000,
visual
inspection
reveals
results,
further
validating
approach.
proposed
underscores
advantages
amalgamating
diverse
models,
highlighting
potential
techniques
enhance
tasks
beyond
individual
capabilities.