Effect of Dual-Doped Hydroxyapatite Nanoparticles Loaded with 5-Fluorouracil on Breast Cancer Treatment Through the Disruption of DNA Replication: In Vitro Drug Release and Kinetics Study DOI

Eswari Thulasimuthu,

Subha Veeramani,

R. Ilangovan

et al.

BioNanoScience, Journal Year: 2024, Volume and Issue: 15(1)

Published: Dec. 18, 2024

Language: Английский

Synergistic effects of iron oxide nanoparticles and indole-3-acetic acid on the germination and development of cold-stored chrysanthemum synthetic seeds DOI
Dariusz Kulus, Alicja Tymoszuk,

Alicja Kulpińska

et al.

Plant Cell Tissue and Organ Culture (PCTOC), Journal Year: 2025, Volume and Issue: 160(1)

Published: Jan. 1, 2025

Language: Английский

Citations

0
Pulsed Alternating Fields Magnetic Hyperthermia in Combination with Chemotherapy (5-Fluorouracil) as a Cancer Treatment for Glioblastoma Multiform: An In Vitro Study DOI Creative Commons
Lilia Souiade, María Rodriguez-Garcia, José Javier Serrano Olmedo

et al.

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(7), P. 556 - 556

Published: April 5, 2025

Inducing magnetic hyperthermia (MHT) involves locally raising the temperature to 39–45 °C, which increases susceptibility of tumor cells therapeutic agents without damaging healthy tissues. Recent studies on trapezoidal pulsed alternating fields (TP-AMFs) have proven their considerable efficacy in increasing nanoparticles (MNPs) compared sinusoidal fields. Thermal therapies been known incorporate multiple combinations approaches optimize medical procedure for healing cancer patients such as chemotherapy and radiotherapy. The combination MHT with aims enhance effects against due synergistic interaction cells. In this study, we aim exploit combining produced by TP-AMFs a low concentration 5-Fluorouracil (5-FU) outcomes comparison alone. Hence, exposed glioblastoma cell line (CT2A) incubated iron oxide at 1 mg/mL two cycles employing trapezoidal-square waveform 200 kHz 2 mT 30 min each cycle, separated 45 break, both single treatment 0.1 μg/mL 5-FU. Our findings demonstrated effect between via 5-FU, death 58.9 ± 2%, 31.4 3% Cell was primarily driven necrosis pathway (47.3 2%) apoptosis (11.6 2). addition 5-FU enhanced cytotoxic CT2A cells, calreticulin (CRT) positive 17 1% 10 Furthermore, suggests that employed approach can promote immune system activation exposure CRT treated

Language: Английский

Citations

0
Superparamagnetic Iron Oxide-Hydroxyapatite Composite Coatings for Bio-Imaging, Hyperthermia and Orthopedic Applications DOI Creative Commons
Smrithi Saroj, U. Vijayalakshmi

Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Exploring Calcium Phosphate-Based Magnetic Nanofluids as Nanoheater: Insights into Magnetic Hyperthermia Application DOI

Eswari Thulasimuthu,

Subha Veeramani,

N. Rajmuhon Singh

et al.

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Language: Английский

Citations

0
Clay-based catalyst for pyrolysis of polypropylene waste into fuels DOI

Gbenga Emmanuel Adekayero,

Magdalena Osial, Olugbenga Oludayo Oluwasina

et al.

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 131030 - 131030

Published: May 1, 2025

Language: Английский

Citations

0
Effect of Dual-Doped Hydroxyapatite Nanoparticles Loaded with 5-Fluorouracil on Breast Cancer Treatment Through the Disruption of DNA Replication: In Vitro Drug Release and Kinetics Study DOI

Eswari Thulasimuthu,

Subha Veeramani,

R. Ilangovan

et al.

BioNanoScience, Journal Year: 2024, Volume and Issue: 15(1)

Published: Dec. 18, 2024

Language: Английский

Citations

2