Mechanistic Insights into the Antioxidant Potential of Sugarcane Vinegar Polyphenols: A Combined Approach of DPPH-UPLC-MS, Network Pharmacology and Molecular Docking DOI Creative Commons

Feifei Wu,

Bo Lin,

Jing Chen

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(21), P. 3379 - 3379

Published: Oct. 24, 2024

This study investigated the antioxidant potential of sugarcane vinegar, an emerging functional food, by analyzing its polyphenols and underlying molecular mechanisms that intervene in oxidative stress. Using a 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH) assay combined with UPLC-MS analysis, six key were identified: chlorogenic acid, caffeic ferulic luteolin, protocatechuic syringic acid. These compounds showed positive correlation capacity. In simulated vinegar environment, these exhibited synergistic effects, while methanol, antagonistic interactions predominant. Network pharmacology revealed five targeting 10 critical proteins involved stress, including PI3K-Akt IL-17 signaling pathways. Molecular docking confirmed strong binding affinities between core targets like PTGS2, STAT3, GSK3B. establishes reference for highlights developing products.

Language: Английский

Natural Antioxidants: Advancing Stability and Performance in Sustainable Biobased and Biodegradable Plastics DOI Creative Commons
Norma Mallegni, Francesca Cicogna, Elisa Passaglia

et al.

Compounds, Journal Year: 2025, Volume and Issue: 5(1), P. 4 - 4

Published: Feb. 3, 2025

The depletion of fossil fuels and environmental concerns have driven the development sustainable materials, including bio-based biodegradable plastics, as alternatives to conventional plastics. Although these plastics aid in waste management climate change mitigation, their vulnerability oxidative degradation impacts longevity, durability, performance. Natural antioxidants such tocopherols, flavonoids, tannins, extracted from plants or agri-food waste, present a alternative synthetic stabilizers by enhancing thermal stability polymers like poly(lactic acid) (PLA), poly(butylene succinate) (PBS), succinate-adipate) (PBSA), adipate-co-terephthalate) (PBAT), poly(hydroxyalkanoate) (PHA), starch-based materials. This review highlights recent advances stabilized with natural antioxidants, mechanisms action, role improving material properties for applications packaging. Additionally, it explores impact on recycling processes, advancements composite production techniques, future research directions. Bioplastics can achieve enhanced performance, reduce support circular economy incorporating antioxidants.

Language: Английский

Citations

5

Examination of the Bioavailability and Bioconversion of Wheat Bran-Bound Ferulic Acid: Insights into Gastrointestinal Processing and Colonic Metabolites DOI
Zhikai Zeng, Yijun Zhu, Yiyun Li

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

The postingestion journey and bioconversion of wheat bran-bound ferulic acid, a known beneficial phytochemical, remain insufficiently understood. This study aims to systematically investigate its bioaccessibility, bioavailability, excretion, colonic metabolism, both

Language: Английский

Citations

2

Comparative metabolomics profiling reveals the unique bioactive compounds and astringent taste formation of rosehips DOI
Meichun Zhou,

Yanlin Sun,

Qingyi Mao

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 452, P. 139584 - 139584

Published: May 7, 2024

Language: Английский

Citations

8

Photophysical Properties of Sinapic Acid and Ferulic Acid and Their Binding Mechanism with Caffeine DOI
Umer Sherefedin,

Abebe Belay,

Kusse Gudishe

et al.

Journal of Fluorescence, Journal Year: 2024, Volume and Issue: unknown

Published: April 9, 2024

Language: Английский

Citations

7

The Mediterranean Species Calendula officinalis and Foeniculum vulgare as Valuable Source of Bioactive Compounds DOI Creative Commons
Filomena Monica Vella, Domenico Pignone, Bruna Laratta

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3594 - 3594

Published: July 30, 2024

Research studies on plant secondary metabolites have increased over the last decades as a consequence of growing consumer demand for natural products in pharmaceutics and therapeutics, well perfumery cosmetics. In this perspective, many Mediterranean species could be an appreciated source bioactive compounds with pharmacological health-promoting properties, including antioxidant, antimicrobial, antiviral, anti-inflammatory, antitumor ones.

Language: Английский

Citations

6

A bibliometric analysis of phenolic acids over the last five years DOI
Leonardo de Freitas Marinho, William Gustavo Sganzerla, Jean Agustín Velásquez Piñas

et al.

Biocatalysis and Agricultural Biotechnology, Journal Year: 2024, Volume and Issue: 56, P. 103044 - 103044

Published: Jan. 29, 2024

Language: Английский

Citations

5

Compositional analysis of baru (Dipteryx alata Vog.) pulp highlighting its industrial potential DOI
Gracieli de Miranda Monteiro, Elisângela Elena Nunes Carvalho, Rafael Carvalho do Lago

et al.

Food Research International, Journal Year: 2025, Volume and Issue: 201, P. 115548 - 115548

Published: Jan. 2, 2025

Language: Английский

Citations

0

Dual microelectromembrane extraction as a tunable platform for the determination of antioxidant compounds with varied hydrophobicity in oral bioaccessibility assays of food commodities: a proof of concept DOI Creative Commons
Ali Sahragard, Carlos Pagan-Galbarro, David J. Cocovi-Solberg

et al.

Analytical and Bioanalytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

An automatic millifluidic dual microelectromembrane extraction (D-µEME) method as a front-end to HPLC-UV-Vis is herein proposed for the first time facilitate matrix clean-up of relatively polar polyphenolic acidic (PPA) antioxidants with broad range lipophilicity (logP from -0.27 2.14) simulated gastric extracts oral bioaccessibility tests. The flow setup amenable handle microliter volumes two distinct organic phases along donor and acceptor unsupervised, conduct in-tube D-µEME in parallel without supporting membranes, mix automatically prior online HPLC-UV-Vis. target involve gallic acid, chlorogenic 4-hydroxybenzoic caffeic trans-cinnamic acid. Various solvents are explored investigate their compatibility simultaneous D-µEME, including 1-pentanol, 1-hexanol, 1-heptanol, 1-octanol, 1-nonanol, well deep eutectic solvents, e.g., thymol/6-methyl coumarin, ionic liquids additives alcohols. Notably, 1-pentanol 1-octanol exhibit best performances extracting most (gallic acid acid) least analytes (trans-cinnamic acid), respectively, notwithstanding both retrieve medium hydrophobicity (4-hydroxybenzoic acid). effects voltage, time, sample strength on recoveries also investigated detail. Under selected conditions, overall linear ranges span 1.25 80 mg/L, limits detection ranging 0.2 3.3 mg/L. flow-based resorted assays phase compounds eggplant, blueberry, coffee bean extracts, relative 71.5 133.5%.

Language: Английский

Citations

0

Prospects of cold plasma in enhancing food phenolics: analyzing nutritional potential and process optimization through RSM and AI techniques DOI Creative Commons
M. Anjaly Shanker, Sandeep Singh Rana

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 15, 2025

Consumption of plant-based food is steadily increasing and follows an augmented trend owing to their nutritive, functional, energy potential. Different bioactive fractions, such as phenols, flavanols, so on, contribute highly the nutritive profile are known have a sensitivity toward higher temperatures. This limits applicability traditional thermal treatments for plant products, paving way advancement innovative non-thermal techniques pulsed electric field, microwave, ultrasound, cold plasma, high-pressure processing. Among these techniques, plasma would be operative choice in applications due efficacy, greenness, chemical exclusivity, quality retention. The efficiency process ensuring potential depends on several factors, feeding gas, input voltage, exposure time, pressure, current flow. review explains detail optimization parameters technique, greater extractability or retention total phenols antioxidant Response surface methodology (RSM) one common involved course factors. It also covers convention artificial intelligence-based methods, neural networks (ANN) genetic algorithms (GA), evaluating data parameters. critically examines strengths each tool determining optimal maximizing phenol activity. ascendancy was mentioned studies regarding fruit, vegetables, they can applied other products.

Language: Английский

Citations

0

Phytochemicals in medicine and food: potential to the development of health products in medicine and food industries DOI Creative Commons
Aline Priscilla Gomes da Silva, Jianbo Xiao, Haiyan Gao

et al.

Phytochemistry Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

Language: Английский

Citations

0