Exploring the Renoprotective Potential of Bioactive Nutraceuticals in Chronic Kidney Disease Progression: A Narrative Review DOI Open Access
Anindita Ghosh, Arti Muley,

Sakshi Bhat

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 5, 2024

Chronic kidney disease (CKD) is a condition that characterized by progressive loss of function over time. A substantial increase in the burden CKD evident globally, attributed to multifactorial conditions like an expanding aging population, rising diabetes and hypertension rates, more significant exposures risk factors associated with environment lifestyle. Nutraceuticals are substances usually considered food or active part provides medical health benefits, including prevention treatment disease. The aim review positive role nutraceuticals managing CKD. narrative generated, extracting papers from databases Web Science, Scopus, ScienceDirect, ResearchGate, PubMed. Animal human trials focusing on effect different initial stage disease, i.e., stages 1, 2, 3 CKD, were included. review's outcome understanding effectiveness have shown results conditions. Active compounds include ubiquinone, curcumin, nitrates, nitrites, lycopene, resveratrol. These bioactive components also beneficial for other comorbid diabetes, hypertension, cardiovascular eminent adverse Lycopene, coenzyme Q10 (CoQ10), resveratrol, flavonoids positively impacted complications. hold great promise individuals coming years, offering diverse potential benefits. delivering vital antioxidant anti-inflammatory support alleviate oxidative stress inflammation, helping regulate blood pressure lipid levels improved health, promoting optimal renal sustain assisting maintaining electrolyte balance, warding off complications, influencing gut microbiota enhanced digestive well-being, ultimately elevating overall quality life, those

Language: Английский

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview DOI Creative Commons
Tabussam Tufail,

Huma Bader Ul Ain,

Sana Noreen

et al.

Food Science & Nutrition, Journal Year: 2024, Volume and Issue: 12(11), P. 8715 - 8741

Published: Oct. 16, 2024

Certain carotene components, such as lycopene and beta-carotene, are found in tomatoes, carrots, sweet potatoes, etc. good for human health. It gives plants their distinctive red color. A class of lipid-soluble natural pigments known carotenoids is the precursor vitamin vital antioxidant defense against peroxides cells tissues. This review provides an overview current state knowledge research on sources, structures, physiochemical properties, absorption metabolism, functional advantages, prevention many diseases associated with beta-carotene. These antioxidants have been linked to a lower risk cardiovascular disease cancer, they also help draw pollinators flowers. Carrots potatoes rich sources which strengthens immune system improves eye The vivid color reproductive organs, including flowers fruits, caused by carotenoid, secondary metabolite that produced plastids. other health advantages attributed lycopene. When ingested through food or supplements, beta-carotene manage prevent number diseases, metabolic, inflammatory, cardiovascular, hepatic, ophthalmic, skeletal, infertility disorders. main point toxicity uncommon, these generally accepted be safe at different doses. Including nutrients your diet can improve general provide illness prevention.

Language: Английский

Citations

15
Phytochemicals in medicine and food: potential to the development of health products in medicine and food industries DOI Creative Commons
Aline Priscilla Gomes da Silva, Jianbo Xiao, Haiyan Gao

et al.

Phytochemistry Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

Language: Английский

Citations

0
Chromatic symphony of fleshy fruits: functions, biosynthesis and metabolic engineering of bioactive compounds DOI Creative Commons
Huimin Hu, Nirakar Pradhan, Jianbo Xiao

et al.

Molecular Horticulture, Journal Year: 2025, Volume and Issue: 5(1)

Published: April 2, 2025

Fleshy fruits are popular among consumers due to their significant nutritional value, which includes essential bioactive compounds such as pigments, vitamins, and minerals. Notably, plant-derived pigments generally considered safe reliable, helping protect humans against various inflammatory diseases. Although the phytochemical diversity biological activities have been extensively reviewed summarized, status of nutrients in fleshy fruits, particularly with a focusing on different colors, has received less attention. Therefore, this review introduces five common types based coloration summarizes major compounds. It also provides latest advancements function, biosynthesis, metabolic engineering pigments. In review, we emphasize that promoting consumption diverse array colorful can contribute balanced diet; however, optimal intake levels still require further clinical validation. This may serve useful guide for decisions enhance understanding natural accelerate application agriculture medicine.

Language: Английский

Citations

0
Exceeding the Limits with Nutraceuticals: Looking Towards Parkinson’s Disease and Frailty DOI Open Access
Martina Montanari, Nicola Biagio Mercuri, Giuseppina Martella

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 26(1), P. 122 - 122

Published: Dec. 26, 2024

One of the most pressing challenges facing society today is rising prevalence physical and cognitive frailty. This geriatric condition makes older adults more vulnerable to disability, illness, a heightened risk mortality. In this scenario, Parkinson’s disease (PD) frailty, which share several common characteristics, are becoming increasingly prevalent worldwide, underscoring urgent need for innovative strategies. Nutraceuticals naturally occurring bioactive compounds contained in foods, offering health benefits over above essential nutrition. By examining literature from past decade, review highlights how nutraceuticals can act as complementary therapies, addressing key processes, such oxidative stress, inflammation, neuroprotection. Notably, antioxidant action appears particularly beneficial regard PD For instance, antioxidant-rich may mitigate damage linked levodopa therapy PD, potentially reducing side effects enhancing treatment sustainability. Similarly, amplify activity, muscle function, health, resilience, thereby proposes holistic approach integrating with exercise, pharmacotherapy, lifestyle adjustments. It promises transform management ARD, prolong life, improve quality life well-being people.

Language: Английский

Citations

1
Potential of Natural Products in the Treatment of Glioma: Focus on Molecular Mechanisms DOI
Amirhossein Sheida,

Marjan Farshadi,

Amirhossein Mirzaei

et al.

Cell Biochemistry and Biophysics, Journal Year: 2024, Volume and Issue: 82(4), P. 3157 - 3208

Published: Aug. 16, 2024

Language: Английский

Citations

0
Exploring the Renoprotective Potential of Bioactive Nutraceuticals in Chronic Kidney Disease Progression: A Narrative Review DOI Open Access
Anindita Ghosh, Arti Muley,

Sakshi Bhat

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 5, 2024

Chronic kidney disease (CKD) is a condition that characterized by progressive loss of function over time. A substantial increase in the burden CKD evident globally, attributed to multifactorial conditions like an expanding aging population, rising diabetes and hypertension rates, more significant exposures risk factors associated with environment lifestyle. Nutraceuticals are substances usually considered food or active part provides medical health benefits, including prevention treatment disease. The aim review positive role nutraceuticals managing CKD. narrative generated, extracting papers from databases Web Science, Scopus, ScienceDirect, ResearchGate, PubMed. Animal human trials focusing on effect different initial stage disease, i.e., stages 1, 2, 3 CKD, were included. review's outcome understanding effectiveness have shown results conditions. Active compounds include ubiquinone, curcumin, nitrates, nitrites, lycopene, resveratrol. These bioactive components also beneficial for other comorbid diabetes, hypertension, cardiovascular eminent adverse Lycopene, coenzyme Q10 (CoQ10), resveratrol, flavonoids positively impacted complications. hold great promise individuals coming years, offering diverse potential benefits. delivering vital antioxidant anti-inflammatory support alleviate oxidative stress inflammation, helping regulate blood pressure lipid levels improved health, promoting optimal renal sustain assisting maintaining electrolyte balance, warding off complications, influencing gut microbiota enhanced digestive well-being, ultimately elevating overall quality life, those

Language: Английский

Citations

0