Meaning in life: bidirectional relationship with depression, anxiety, and loneliness in a longitudinal cohort of older primary care patients with multimorbidity

BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 24, 2025

Abstract Background Depression, anxiety and loneliness are common among older patients. As a potential psychological buffer against these challenges, meaning in life (MIL) remains underexplored longitudinal studies within this population. This study aims to examine the relationship of MIL with depression, anxiety, adults multimorbidity Hong Kong. Methods In prospective cohort 1077 primary care patients aged 60 or above Kong, was assessed using an item from Chinese Purpose Life test at baseline, 1st follow-up (median: 1.3 years), 2nd 3.1 years). were Patient Health Questionnaire, Generalized Anxiety Disorder, De Jong Gierveld Loneliness scales, respectively, each time point. Cross-lagged relationships between measures examined cross-lagged panel models. Results Participants had average age 70.0 years, 70.1% being female. Higher predicted lower depression (β = -0.15), -0.13), overall -0.18), emotional social -0.16) follow-up. Additionally, higher -0.12), -0.11), -0.10) At -0.21), but not follow-up, -0.23), -0.16), -0.10), loneliness, Conclusions The findings suggest bidirectional mental health outcomes Emotional demonstrated more consistent association than loneliness. Further research is needed understand underlying mechanisms develop targeted interventions addressing both problems.

Language: Английский

Depressive/Anxiety Symptoms in Homebound Older Adults: Mediation Effects of Loneliness and Psychological Well-Being

Clinical Gerontologist, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: April 17, 2025

To examine the direct effect of a homebound state (defined as never/rarely going outside home in preceding month) on depressive/anxiety symptoms and mediation loneliness psychological well-being associations between symptoms. Data came from 2023 National Health Aging Trend Study (N = 7,547 community-dwelling Medicare beneficiaries age 65+). We fitted path model to research questions. test statistical significance effect, we used bootstrapped analysis obtain estimates indirect effects their 95% CIs. found significant effects. The ratio (0.13) total was 0.14. (0.28) 0.26. Loneliness well-being, or lack thereof, significantly mediate relationship depression/anxiety older adults. Interventions decrease improve among adults are needed alleviate depression/anxiety.

Language: Английский