Biological markers of adipose tissue: Adipokines DOI

Jean‐Philippe Bastard,

Imane Dridi-Brahimi,

Camille Vatier

et al.

Annales d Endocrinologie, Journal Year: 2024, Volume and Issue: 85(3), P. 171 - 172

Published: April 16, 2024

Language: Английский

Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue DOI Creative Commons
Zhiqi Huang,

Ziyang Zhao,

H. C. Shi

et al.

Chinese Medicine, Journal Year: 2025, Volume and Issue: 20(1)

Published: May 9, 2025

Language: Английский

Citations

0
Associated factors and principal pathophysiological mechanisms of type 2 diabetes mellitus DOI Creative Commons
Luyao Wang, Lianxin Li, Jiaxin Liu

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: May 9, 2025

Type 2 diabetes mellitus(T2DM) as a common chronic disease with an increasing prevalence worldwide that poses great threat to individual health, and is characterized by hyperglycemia resulting from insulin resistance (IR) coupled β-cell dysfunction. Mitochondrial dysfunction, obesity, gut microbiota, oxidative stress inflammation have emerged significant contributor the etiology of T2DM, affecting various metabolic processes critical for glucose homeostasis. This short review underscores their role in enhancing T2DM-related molecular mechanisms explores recent advancements diabetic management, further highlights importance personalized care plans address complexities T2DM aims improve patient quality life long-term health outcome.

Language: Английский

Citations

0
Heat stress reduces brown adipose tissue activity by exacerbating mitochondrial damage in type 2 diabetic mice DOI Creative Commons

Penghua Lai,

Linlin Zhang,

Qiu Yan

et al.

Journal of Thermal Biology, Journal Year: 2024, Volume and Issue: 119, P. 103799 - 103799

Published: Jan. 1, 2024

Epidemiological evidence shows that diabetic patients are susceptible to high temperature weather, and brown adipose tissue (BAT) activity is closely related type 2 diabetes (T2DM). Activation of BAT under cold stress helps improve T2DM. However, the impact on still unclear. The study aimed investigate heat glucose lipid metabolism in T2DM mice by influencing activity. High-fat feeding injecting streptozotocin (STZ) induced model mice. All were randomly divided into three groups: a normal(N) group, (DM) group (DMHS) group. DMHS received intervention for 3 days. Fasting blood glucose, fasting serum insulin lipids measured all groups. was assessed using quantitative real-time PCR (qRT-PCR), electron microscopy, PET CT. Furthermore, UHPLC-Q-TOF MS technique employed perform metabolomics analysis both DM results this indicated aggravated dysregulation metabolism, exacerbated mitochondrial dysfunction reduced This may be abnormal accumulation branched-chain amino acids (BCAAs) mitochondria BAT.

Language: Английский

Citations

3
High-altitude environments enhance the ability of Eothenomys miletus to regulate body mass during food limitation, with a focus on gut microorganisms and physiological markers DOI Creative Commons
Tianxin Zhang, Ting Jia, Wanlong Zhu

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 1, 2024

Animals' digestion, energy metabolism, and immunity are significantly influenced by interactions between the gut microbiota intestinal environment of host. Previous studies have shown that

Language: Английский

Citations

3
Biological markers of adipose tissue: Adipokines DOI

Jean‐Philippe Bastard,

Imane Dridi-Brahimi,

Camille Vatier

et al.

Annales d Endocrinologie, Journal Year: 2024, Volume and Issue: 85(3), P. 171 - 172

Published: April 16, 2024

Language: Английский

Citations

2