Engineering of Brewery Waste-Derived Graphene Quantum Dots with Zno Nanoparticles for Treating Multi-Drug Resistant Bacterial Infections DOI

Lekshmi Chandran,

Agnieszka Krzemińska,

Sathyavathi Sudararaju

et al.

Published: Jan. 1, 2024

Multidrug-resistant microbial infections represent a serious hazard to human health and have proven difficult treat in clinical settings. In this study, the antibacterial efficiency of graphene quantum dots (GQDs) derived from brewery spent grain combination with zinc oxide (ZnO) nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA) isolated wound specimens is investigated for first time. The crystallinity, d-spacing, π-π stacking nanomaterials were confirmed by X-ray diffraction analysis. underlying sheet-like morphology BSG-derived reduced (BrGO) was revealed using field emission scanning electron microscopy. Raman analysis evidenced an ID/IG ratio 0.95 BrGO, which indicates higher degree structural defects disorder, while ZnO/GQDs composite, blue shift E2H peak indicated decrease particle size strain crystal structure. high-resolution transmission microscopy used investigate layered structure average GQDs (27 nm). Interestingly, composites showed better activity compared individual ZnO, against, Escherichia coli, aureus. also demonstrated significant disinfecting MRSA (ATCC isolates specimens). Density functional theory (DFT) calculations substantial clustering groups at edges nanomaterial. disinfection mechanism elucidated time DFT calculations. Cytotoxicity experiments 3T3 mouse embryo fibroblasts testified that are not toxic mammalian cells concentrations up 50 ug/mL.

Language: Английский

Engineering of brewery waste-derived graphene quantum dots with ZnO nanoparticles for treating multi-drug resistant bacterial infections DOI

G.S. Lekshmi,

Agnieszka Krzemińska,

Sathyavathi Sundararaju

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(2), P. 112263 - 112263

Published: Feb. 20, 2024

Language: Английский

Citations

6
Engineering of Brewery Waste-Derived Graphene Quantum Dots with Zno Nanoparticles for Treating Multi-Drug Resistant Bacterial Infections DOI

Lekshmi Chandran,

Agnieszka Krzemińska,

Sathyavathi Sudararaju

et al.

Published: Jan. 1, 2024

Multidrug-resistant microbial infections represent a serious hazard to human health and have proven difficult treat in clinical settings. In this study, the antibacterial efficiency of graphene quantum dots (GQDs) derived from brewery spent grain combination with zinc oxide (ZnO) nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA) isolated wound specimens is investigated for first time. The crystallinity, d-spacing, π-π stacking nanomaterials were confirmed by X-ray diffraction analysis. underlying sheet-like morphology BSG-derived reduced (BrGO) was revealed using field emission scanning electron microscopy. Raman analysis evidenced an ID/IG ratio 0.95 BrGO, which indicates higher degree structural defects disorder, while ZnO/GQDs composite, blue shift E2H peak indicated decrease particle size strain crystal structure. high-resolution transmission microscopy used investigate layered structure average GQDs (27 nm). Interestingly, composites showed better activity compared individual ZnO, against, Escherichia coli, aureus. also demonstrated significant disinfecting MRSA (ATCC isolates specimens). Density functional theory (DFT) calculations substantial clustering groups at edges nanomaterial. disinfection mechanism elucidated time DFT calculations. Cytotoxicity experiments 3T3 mouse embryo fibroblasts testified that are not toxic mammalian cells concentrations up 50 ug/mL.

Language: Английский

Citations

0