Review on analytical technologies and applications in metabolomics

Biocell, Journal Year: 2024, Volume and Issue: 48(1), P. 65 - 78

Published: Jan. 1, 2024

Over the past decade, swift advancement of metabolomics can be credited to significant progress in technologies such as mass spectrometry, nuclear magnetic resonance, and multivariate statistics. Currently, garners widespread application across diverse fields including drug research development, early disease detection, toxicology, food nutrition science, biology, prescription, chinmedomics, among others. Metabolomics serves an effective characterization technique, offering insights into physiological process alterations in vivo. These changes may result from various exogenous factors like environmental conditions, stress, medications, well endogenous elements genetic protein-based influences. The potential scientific outcomes gleaned these have catalyzed formulation innovative methods, poised further broaden scope this domain. Today, has evolved a valuable widely accepted instrument life sciences. However, comprehensive reviews focusing on sample preparation analytical methodologies employed within sciences are surprisingly scant. This review aims fill that gap, providing overview current trends recent advancements metabolomics. Particular emphasis is placed preparation, sophisticated techniques, their applications science research.

Language: Английский

Application of UPLC-Q Exactive™ HF-X MS-based untargeted metabolomics reveals variations in Moringa oleifera Lam. leaves from different regions

Biochemical Systematics and Ecology, Journal Year: 2024, Volume and Issue: 115, P. 104847 - 104847

Published: May 17, 2024

Language: Английский