Statistical simplex centroid experimental design and formulation maps to predict the stability in cosmetic emulsions containing commercial emulsifiers

Journal of Surfactants and Detergents, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Abstract Formulating cosmetic products to meet consumer expectations poses significant challenges in terms of stability and shelf life. This work evaluates emulsions formulated with three commercial emulsifiers: Polyglyceryl‐3 distearate (Dermofeel®, a biobased surfactant), Glyceryl stearate (50%)/PEG‐100 (50%) (Lipomulse®, nonionic mixture glyceryl ethoxylated surfactants), Potassium cetyl phosphate (Amphisol K®, an anionic surfactant). Additionally, emollients, namely Caprylic/Capric Triglyceride, Isoamyl Cocoate, Jojoba Oil, were incorporated into the formulations. The effect emulsion composition on stability, droplet size, rheology, texture was systematically assessed via experiments multivariate regression modeling, thereby providing objective tool for formulation. lifetime showed that containing exhibited separation velocities larger than 60 μm/s, whereas those other emulsifiers below 40 indicating lifetimes. A predictive model based statistical simplex centroid experimental design developed evaluate velocity system, enabling assessment important variables influence stability. results indicate (such as oil concentration) formulation surfactant nature type) are determining but also secondary effects such surfactant‐emollient interactions crucial predict emulsions.

Language: Английский

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Triterpenoid Saponins from Washnut (Sapindus mukorossi Gaertn.)—A Source of Natural Surfactants and Other Active Components

Plants, Journal Year: 2022, Volume and Issue: 11(18), P. 2355 - 2355

Published: Sept. 9, 2022

Sapindus mukorossi Gaertn., also called the washnut, is a tropical tree of Sapindaceae family. The plant owes its name to cleaning and washing properties used by local population as natural detergent. most important ingredients are triterpenoid saponins contained in many parts plant, inducing fruits, galls, or roots. contains other valuable, biologically active compounds that obtained extraction methods. Raw purified extract isolated valuable products can be food, pharmaceutical, cosmetic, chemical industries. This review includes biological surfactant extracts from various plant.

Language: Английский

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Characterisation of cytotoxicity and immunomodulatory effects of glycolipid biosurfactants on human keratinocytes

Applied Microbiology and Biotechnology, Journal Year: 2022, Volume and Issue: 107(1), P. 137 - 152

Published: Nov. 28, 2022

Skin irritation and allergic reactions associated with the use of skincare products formulated synthetically derived surfactants such as sodium lauryl ether sulphate (SLES) have encouraged search for naturally biocompatible alternatives. Glycolipid biosurfactants sophorolipids (SL) rhamnolipids (RL) offer a potential alternative to SLES. However, most studies on bioactive properties microbial glycolipids were determined using their mixed congeners, resulting in significant inter-study variations. This study aims compare effects highly purified SL (acidic lactonic) RL (mono-RL di-RL) congeners SLES spontaneously transformed human keratinocyte cell line (HaCaT cells) assess glycolipids' safety applications. Preparations acidic 100% pure, lactonic mono-RL 96% di-RL 97% pure. Cell viability XTT assays, morphological analyses, immunoassays revealed that differing HaCaT cells dependent chemical structure. Compared SLES, negligible viability, morphology, production pro-inflammatory cytokines. Furthermore, at non-inhibitory concentrations, significantly attenuated IL-8 CXCL8 expression while increasing IL-1RA IL1RN lipopolysaccharide-stimulated cells. Although further would be required, these results demonstrate innocuous compounds, could provide substitute synthetic formulations perform immunopharmacological roles topical skin infections psoriasis. KEY POINTS: • Purified glycolipid keratinocytes. mono-rhamnolipids Di-rhamnolipids modulate cytokine lipopolysaccharide stimulated

Language: Английский

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Implementation of sustainable development goals in the cosmetics industry based on the example of cleansing cosmetics containing a surfactin-rich digestate extract

Clean Technologies and Environmental Policy, Journal Year: 2023, Volume and Issue: 25(9), P. 3111 - 3125

Published: June 23, 2023

Abstract The implementation of sustainable development goals in the cosmetics industry is focused primarily on phase product design and formulation fully functional based raw materials natural origin. aim present study was to evaluate feasibility using a surfactin-rich digestate extract—a material biotechnological origin—as an ingredient cleansing cosmetics. A composition designed, shower gels extract were formulated. In next stage study, prototypical products subjected quality assessment with emphasis properties determining their functionality safety use by consumers. formulated origin addition show acceptable including viscosity, foaming ability fat emulsification properties. Importantly, found significantly improve evaluated cosmetic prototypes. This finding corroborated significant decrease zein value, which measure irritant effect formulations. slight emulsify fats for tested prototypes confirmed appropriate mild skin. Through extract, acquired color derived from extract. Colorimetric analysis shows that changes samples should be noticeable even inexperienced observers. Graphical

Language: Английский

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Meta-Analysis and Analytical Methods in Cosmetics Formulation: A Review

Cosmetics, Journal Year: 2023, Volume and Issue: 11(1), P. 1 - 1

Published: Dec. 19, 2023

The ever-evolving cosmetic industry requires advanced analytical techniques to explore, understand, and optimize product performance at nano, micro, macroscopic levels. Nowadays, these insights are crucial for translating microstructure behavior into properties. This knowledge is essential formulate products with a lower carbon footprint higher sustainability profile, incorporating, the same time, natural or biobased raw materials. These materials may present challenges formulators scientists due either an inferior when compared their fossil-derived counterparts costs. comprehensive review covers spectrum of methodologies employed in formulation, including chromatographic analyses, olfactometry, electronic nose technology. characterization stability involving assessing parameters such as droplet size, zeta potential, viscosity, centrifugation, surface tension, interfacial tension also explored. discussion this paper extends role rheology understanding molecular structure behavioral dynamics samples. concludes overview colorimetric analysis, aspect related consumer perception, followed by on opportunities associated using meta-analysis cosmetics. formulation cosmetics employing feedstocks included, highlighting evolving landscape science integration sustainable practices. stands interface between performance, which attained through detailed examination each method. know-how shared serves valuable resource formulators, researchers, professionals real-world applications field formulation.

Language: Английский

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Evaluation of Cosmetic and Dermatological Properties of Kombucha-Fermented Berry Leaf Extracts Considered to Be By-Products

Molecules, Journal Year: 2022, Volume and Issue: 27(7), P. 2345 - 2345

Published: April 6, 2022

Leaves of Rubus fruticosus L., Vaccinum myrtillus Ribes nigrum L. and Fragaria vesca are considered agro-waste the berry industry, but they can be a rich source valuable bioactive compounds used in cosmetic industry. In this study, kombucha-fermented non-fermented extracts were compared terms chemical composition biological activity. Polyphenol identified by HPLC/DAD/ESI-MS. The antioxidant potential was analyzed evaluating scavenging intracellular free radicals contained keratinocytes fibroblasts DPPH ABTS assay, obtaining higher radical capacity for ferments, especially R. V. ferments. Assessment cytotoxicity on skin cell lines showed their positive effect viability (especially ferments after 10 days fermentation). anti-ageing properties determined ability to inhibit activity metalloproteinases, almost 30% inhibition collagenase elastase case fermented myrtillus. Moreover, when samples applied skin, hydration pH demonstrated, which indicates that kombucha leaf may an innovative ingredient.

Language: Английский

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Biomedical engineering aspects of nanocellulose: a review

Nanotechnology, Journal Year: 2022, Volume and Issue: 33(36), P. 362001 - 362001

Published: May 16, 2022

Abstract Cellulose is one of the most abundant renewable biopolymer in nature and present as major constituent both plant cell walls well synthesized by some microorganisms extracellular products. In systems, cellulose self-assembles into a hierarchical ordered architecture to form micro nano-fibrillated structures, on basis which it classified various forms. Nanocellulose (NCs) exist rod-shaped highly crystalline nanocrystals high aspect ratio nanofibers, micro-fibrillated bacterial (BC), depending upon origin, structural morphological properties. Moreover, NCs have been processed diversified products ranging from composite films, coatings, hydrogels, aerogels, xerogels, organogels, rheological modifiers, optically active birefringent colored films using traditional-to-advanced manufacturing techniques. With such versatility structure-property, profound application areas healthcare, packaging, cosmetics, energy, food, electronics, bioremediation, biomedicine with promising commercial potential. Herein this review, we highlight recent advancements synthesis, fabrication, processing NCs, strategic chemical modification routes tailor its properties for targeted biomedical applications. We also study basic mechanism models biosynthesis microbial systems understand insights NC polymorphism. The kinetics enzymatic/chemical modifications growth behavior BC under reactor configurations are studied. challenges associated aspects industrial scale production pristine functionalized meet growing demands market discussed prospective strategies mitigate them described. Finally, post evaluation biological inherent important determine their efficacy development technologies directed

Language: Английский

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Sustainable approach to natural makeup cosmetics containing microencapsulated butterfly pea anthocyanins

Sustainable Chemistry and Pharmacy, Journal Year: 2023, Volume and Issue: 32, P. 101005 - 101005

Published: Jan. 25, 2023

Language: Английский

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Smart Tissue Carriers for Innovative Cosmeceuticals and Nutraceuticals

Cosmetics, Journal Year: 2024, Volume and Issue: 11(1), P. 20 - 20

Published: Feb. 2, 2024

The present review was conducted to investigate the possibilities in realizing novel nanostructured tissues containing functional molecules that can be commercialized as solid products (without using emulsifiers and preservatives) for cosmeceutical nutraceutical applications. After considering principal concepts regarding skin mucous features physiologies, bio-based, biodegradable biocompatible materials explored by investigating correlations between their structures morphologies with respect characteristics of extracellular matrix (ECM). Regarding new smart type tissues, possible composition reviewed relation aging process current contest novel, innovative cosmeceuticals nutraceuticals consider “beauty from within” concept. barriers development these were mainly identified due necessity defining claim green products. Moreover, market growth data highlighted support idea diffusion tissue-based is an opportunity sustainable industrial chains bioeconomies.

Language: Английский

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Marine cosmetics and the blue bioeconomy: from sourcing to success stories

iScience, Journal Year: 2024, Volume and Issue: 27(12), P. 111339 - 111339

Published: Nov. 7, 2024

As the global population continues to grow, so does demand for longer, healthier lives and environmentally responsible choices. Consumers are increasingly drawn naturally sourced products with proven health wellbeing benefits. The marine environment presents a promising yet underexplored resource cosmetics industry, offering bioactive compounds potential safe biocompatible ingredients. This manuscript provides comprehensive overview of organisms production, highlighting marine-derived their applications in skin/hair/oral-care products, cosmeceuticals more. It also lays down critical safety considerations addresses methodologies sourcing compounds, including harvesting, biorefinery concept, use systems biology enhanced product development, relevant regulatory landscape. review is enriched by three case studies: design macroalgal skincare Iceland, establishment microalgal spin-off Italy, utilization proteins cosmeceutical applications.

Language: Английский

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