Journal of Bacteriology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 23, 2025
ABSTRACT
Francisella
tularensis
is
one
of
the
most
virulent
bacterial
pathogens
known
and
causes
disease
tularemia,
which
can
be
fatal
if
untreated.
This
zoonotic
intracellular
pathogen
exposed
to
diverse
environmental
host
stress
factors
that
require
an
appropriate
response
survive.
However,
tolerance
mechanisms
used
by
F.
persist
are
not
fully
understood.
To
address
this
aspect,
we
evaluated
highly
conserved
u
niversal
s
tress
p
rotein
(Usp)
encoded
a
single-copy
gene
in
,
unlike
majority
other
produce
several
many
Usp
homologs.
We
determined
transcript
unusually
stable
with
half-life
over
30
minutes,
usp
protein
levels
remained
abundant
when
low
pH,
nutrient
deprivation,
hydrogen
peroxide,
paraquat.
Of
these
conditions
evaluated,
Δ
mutant
only
exhibited
reduced
survival
relative
wild
type
during
stationary
phase
exposure
paraquat,
toxic
compound
generates
superoxide
anions
free
radicals.
Comparison
untreated
paraquat-treated
indicated
contributes
enhanced
expression
antioxidant
defense
genes,
oxyR
katG
.
In
summary,
high
abundance
stability
provide
prompt
protection
extended
periods
growth
arrest
radical
exposure,
promoting
persistence.
propose
adaptive
prolongs
viability
increases
longevity
environment.
IMPORTANCE
classified
as
Tier
1
select
agent
due
infectious
dose,
ease
transmission,
potential
use
bioweapon.
better
understand
contribute
ability
persist,
(Usp).
show
remains
abundant,
regardless
tested,
differing
from
also
enhances
critical
genes
paraquat
arrest.
Determining
promote
persistence
environment
needed
prevent
tularemia
transmission.
Siembra,
Journal Year:
2025,
Volume and Issue:
12(1), P. e7320 - e7320
Published: Feb. 21, 2025
La
agricultura
convencional
se
caracteriza
por
el
uso
excesivo
de
maquinarias,
agroquímicos
y
prácticas
poco
cuidadosas
con
ambiente.
El
objetivo
esta
investigación
fue
determinar
efecto
los
herbicidas
(glifosato
paraquat)
sobre
la
población
microorganismos
rizósferos
en
cultivo
Theobroma
cacao
L.,
parroquia
Luz
América,
Ecuador.
realizó
periodo
junio-noviembre
2019;
un
siete
años
edad,
sembrado
arreglo
4x4
m,
6,36%
materia
orgánica,
suelo
franco
limo
arcilloso
pH
5,93;
manejo
idéntico
toda
plantación.
Los
tratamientos
fueron;
T1
=
Herbicida
sistémico-glifosato
(1,5
l
ha-1);
T2
contacto-paraquat
T3
Control
mecánico-chapeadora-testigo;
cada
uno
seis
repeticiones.
Se
tomaron
tres
submuestras
enviaron
a
laboratorios
del
Instituto
Nacional
Investigaciones
Agropecuarias
[INIAP].
Las
variables
medidas
desarrollo
poblacional;
identificación
género;
poblacional
hongos
muestra.
análisis
estadístico
Tinn-R.
día
28
marcó
diferencia
significativa
entre
todas
las
observaciones
(P-valor=0,0269);
presencia
tuvo
mayor
concentración
cuando
utilizó
paraquat
(1.894.001
UFC
ml-1).
identificó
Trichoderma
(mayor
Fusarium
glifosato);
al
evaluar
hongos.
Considerando
días
observación,
confirmó
que
disminuye
proporción
su
aplica
glifosato.
concluyó
dos
elevan
Fusarium,
aunque
menor
proporción,
vez
este
promueve
Trichoderma.
Annals of Medicine and Surgery,
Journal Year:
2025,
Volume and Issue:
87(4), P. 2421 - 2425
Published: Feb. 27, 2025
Introduction
and
importance:
Paraquat
(PQ)
poisoning
is
a
life-threatening
condition
with
high-mortality
rate.
As
it
lacks
specific
antidote,
treatment
mainly
supportive,
focusing
on
reducing
oxidative
damage
organ
dysfunction.
Despite
aggressive
intervention,
the
can
rapidly
progress
to
multiorgan
failure.
This
report
presents
fatal
case
of
PQ
poisoning,
highlighting
its
clinical
course
management
challenges.
Case
presentation:
A
45-year-old
female
ingested
10
mL
20%
PQ,
presenting
vomiting,
dizziness,
generalized
body
aches.
At
presentation,
she
was
alert,
stable
vital
signs
no
significant
findings.
Immediate
treatment,
including
gastric
lavage,
activated
charcoal,
corticosteroids,
antioxidants,
monitoring
renal
hepatic
function,
initiated.
On
Day
2,
her
deteriorated
jaundice,
respiratory
distress,
PQ-induced
tongue
ulcers.
Lab
results
showed
worsening
She
received
cyclophosphamide,
N
-acetylcysteine,
heparin-free
hemodialysis,
but
continued
decline,
leading
succumbed
fourth
day.
Clinical
discussion:
toxicity
causes
stress,
resulting
in
rapid
progression
Early
decontamination
supportive
care
are
key,
curative
exists.
The
limited
effectiveness
current
therapies
make
difficult.
Conclusion:
remains
critical
medical
emergency
Timely
recognition,
care,
further
research
into
novel
detoxification
therapeutic
strategies
essential
improving
survival
outcomes.
Additionally,
public
health
measures,
stricter
regulations
increased
awareness
regarding
PQ’s
toxicity,
crucial
preventing
future
cases.
Frontiers in Agronomy,
Journal Year:
2025,
Volume and Issue:
7
Published: March 25, 2025
Hazelnut
(
Corylus
avellana
L.)
plays
a
crucial
role
in
the
agricultural
landscape
of
Oregon's
Willamette
Valley,
where
weed
and
sucker
management
are
labor-intensive
time-consuming
endeavors.
Current
control
strategies
either
costly
but
effective,
ineffective,
or
environmentally
unfriendly.
Tiafenacil,
relatively
new
herbicide,
could
be
an
effective
solution.
Field
studies
were
conducted
commercial
hazelnut
orchards
across
Valley
to
evaluate
efficacy
tiafenacil
for
control.
The
results
confirmed
that
applied
three
times
per
season
up
200
g
ai
ha
-1
did
not
injure
tree
trunk
canopy
had
no
adverse
effects
on
growth
parameters,
chlorophyll
fluorescence,
yield.
Tiafenacil
at
50
outperformed
carfentrazone
35
controlling
prostrate
knotweed
Polygonum
aviculare
L.),
wild
carrot
Daucus
carota
Canada
thistle
Cirsium
arvense
L.
Scop).
However,
was
less
than
glufosinate
1,050
effectively
managed
suckers
comparable
manual
removal
with
superior
carfentrazone.
combined
2,4-D
1,060
improved
compared
alone
same
rate,
suggesting
its
is
enhanced
mixtures.
Importantly,
exhibited
excellent
compatibility
glufosinate,
making
it
practical
option
improving
strategies.
For
growers,
incorporating
into
their
programs—either
as
standalone
treatment
combination
2,4-D—offers
alternative
while
maintaining
strong
These
findings
support
valuable
addition
programs,
especially
when
used
other
herbicides
without
compromising
health.
While
antagonistic
observed
mixed
2,4-D,
further
research
necessary
explore
potential
interactions
herbicides.
Additionally,
economic
viability
herbicide
combinations
should
evaluated
before
broad
adoption.
Toxicology Reports,
Journal Year:
2023,
Volume and Issue:
11, P. 273 - 282
Published: Sept. 19, 2023
Pesticides
are
chemicals
used
to
control
pests
with
sometime
harmful
effects
on
human
health.
This
paper
presents
results
of
self-reported
health
experienced
by
cotton
farmers
in
the
Central-West
region
Burkina
Faso.
It
was
a
cross-sectional
survey
conducted
from
October
December
2021
among
585
consenting
conventional
and
organic
farmers.
Data
collected
included
pesticides
used,
they
use
conditions,
farming
practices,
effects.
Binary
logistic
regression
find
relationships
between
type
produced.
Results
showed
that
all
(100%)
reported
using
synthetic
compared
ones
who
only
natural
insecticides.
Both
occurred
at
least
once
since
started
pesticides,
involving
skin
(85.27%
conventional,
65.52%
organic),
nervous
(88.95%
48,71%
respiratory
(88.10%
67.67%
organic)
systems.
99.72%
vs
46.98%
irritation
following
pesticide
use.
69.97%
35.34%
acute
signs
such
as
severe
headaches.
In
univariate
multivariate
regressions,
headaches,
dizziness,
skin,
ocular
were
significantly
associated
(p
<
0.05).
There
significant
relationship
vomiting
=
0.014),
diarrhea
0.003)
experience
Among
farmers,
there
no
insecticides
headaches
0.01),
rhinitis
0.006),
cough
0.0001),
irritations
0.007)
frequency
per
year
Study
producers
same
types
However,
these
ones.
Agricultural Science and Technology,
Journal Year:
2024,
Volume and Issue:
16(2), P. 75 - 85
Published: June 1, 2024
Abstract.
Pesticide
residues
in
soils
and
farmlands
have
long
been
an
important
concern
agricultural
safety.
In
developing
countries,
ignorance
illiteracy
among
untutored
farmers
greatly
contributed
to
this
issue,
as
several
pesticides
(herbicides,
insecticides,
etc.)
can
leave
the
soil.
The
study
was
carried
out
selected
arable
farms
Ogbomoso
South
Local
Government
Area
of
Oyo
state
evaluate
determine
possibility
pesticide
who
are
fond
using
crop
production.
Questionnaires
were
administered
area
soil
samples
collected
from
some
owned
by
interviewed
found
relevant
usage
history.
Additionally,
with
no
records
which
served
control.
Subsequently,
these
then
taken
laboratory
for
analysis
residue.
average
pH
5.56
mg/kg
5.63
those
usage,
respectively.
level
metabolites
d-BHC,
Chlorothalonil,
Alachlor,
Aldrin,
Dacthal,
Heptachlor
epoxide,
g-Chlordane,
Trans-nonachlor
lands
where
there
none
used
32.41
39.27
mg/kg,
0.62
1.05
1.39
2.14
N.D
1.5
3.91
10.65
5.43
7.62
6.68
7.47
4.78
6.4
results
showed
that
left
standard
measuring
amount
(whether
low
or
high)
is
still
unavailable
literature
most
importantly
many
herbicides
use
within
area.
Since
a
leftover
chemical
residue
soil,
therefore
need
quality
assurance
body
what
placed
on
table
consumers
markets
currently
lacking
food
supply
chain
Nigeria
if
not
Africa.
conclusion,
public
awareness
education
know
dangers
inherent
so
precautionary
measures
will
be
application
pesticides.
