Effects of household air pollution and healthy lifestyle associated with gestational diabetes mellitus DOI Creative Commons

Lulu Dai,

Tao Lin,

Dengqing Liao

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 1, 2024

This study investigated the effect of household air pollution on pregnant women with GDM, and assessed modifying a healthy lifestyle this relationship. Household solid fuel exposure was defined as using fuels (coal, crop residue, wood) for cooking heating. Four individually modifiable factors were in early pregnancy: body mass index, diet, sleep, vitamin D supplementation. Multifactorial logistic regression modeling used to assess relationship between GDM. A stratified analysis additive interaction tested effects scores. After adjusting potential confounders, we found that heating significantly associated an increased risk GDM (adjusted OR = 1.60, 95% CI 1.18-2.18). showed decreasing trend medium versus high score group when compared low group, consistent regardless type 0.39, 0.27-0.57) 0.12, 0.05-0.28), respectively. Importantly, increased, no longer higher risk. There negative (FERI: -5.10 [-16.48, -2.04]; AP: -1.29 [-2.80, -0.39]; SI: -0.37 [-0.20, -0.67]). We determined may be important factor. In addition, have protective exposed indoor pollution.

Language: Английский

Gestational Exposure to PM2.5 and Specific Constituents, Meconium Metabolites, and Neonatal Neurobehavioral Development: A Cohort Study DOI
Zhonghua Lu, Chong Liu, Yujie Chen

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(23), P. 9980 - 9990

Published: May 31, 2024

Exposure to fine particulate matter (PM2.5) during pregnancy has been inversely associated with neonatal neurological development. However, the associations of exposure specific PM2.5 constituents development remain unclear. We investigated these and examined mediating role meconium metabolites in a Chinese birth cohort consisting 294 mother–infant pairs. Our results revealed that its (i.e., organic matter, black carbon, sulfate, nitrate, ammonium) second trimester, but not first or third was total behavioral assessment (NBNA) scores. The constituent mixture trimester also NBNA scores, sulfate identified as largest contributor. Furthermore, metabolome analysis four metabolites, namely, threonine, lysine, leucine, saccharopine, were both Threonine an important mediator, accounting for considerable proportion (14.53–15.33%) observed inverse associations. findings suggest maternal may adversely affect development, which play role.

Language: Английский

Citations

2
Effects of household air pollution and healthy lifestyle associated with gestational diabetes mellitus DOI Creative Commons

Lulu Dai,

Tao Lin,

Dengqing Liao

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 1, 2024

This study investigated the effect of household air pollution on pregnant women with GDM, and assessed modifying a healthy lifestyle this relationship. Household solid fuel exposure was defined as using fuels (coal, crop residue, wood) for cooking heating. Four individually modifiable factors were in early pregnancy: body mass index, diet, sleep, vitamin D supplementation. Multifactorial logistic regression modeling used to assess relationship between GDM. A stratified analysis additive interaction tested effects scores. After adjusting potential confounders, we found that heating significantly associated an increased risk GDM (adjusted OR = 1.60, 95% CI 1.18-2.18). showed decreasing trend medium versus high score group when compared low group, consistent regardless type 0.39, 0.27-0.57) 0.12, 0.05-0.28), respectively. Importantly, increased, no longer higher risk. There negative (FERI: -5.10 [-16.48, -2.04]; AP: -1.29 [-2.80, -0.39]; SI: -0.37 [-0.20, -0.67]). We determined may be important factor. In addition, have protective exposed indoor pollution.

Language: Английский

Citations

1