
Chemosphere, Journal Year: 2024, Volume and Issue: 368, P. 143759 - 143759
Published: Nov. 1, 2024
The increasing consumption of medicines and the lack efficient technologies in wastewater treatment plants (WWTPs) can release pharmaceutically active compounds (PhACs) into any given river with subsequent risk to environment human health. To assess occurrence transfer pathways PhACs through ecosystem, 22 one metabolite were analyzed WWTPs, sediments fish collected alongside Tagus River basin between 2020 2022. All matrices presented at least two drugs being azithromycin only quantified all them. Analgesics, anti-inflammatories, antihypertensives, antidepressants beta-blockers main influents, median concentrations up 19 μg/L. In effluents, antihypertensives highest contribution. For acetaminophen, ibuprofen, ketoprofen, naproxen, atorvastatin, azithromycin, clarithromycin, sulfamethoxazole, trimethoprim, valsartan WWTPs treatments reached removal efficiencies above 75%. Compounds a high tendency bind organic matter retained sludge (clotrimazole, 96 ng/g before digester, 100%). However, results showed that applied not effective removing from this matrix. Although total mass balance revealed rate some PhACs, many them still present effluent their rivers became source PhAC pollution aquatic ecosystem. most hydrophobic ones (irbesartan, 24 ng/g, 61%), positively charged (o-desmethylvenlafaxine, 95 68%) those affinity 21 61%) sediment samples. Only clotrimazole (7.8 ng/g) (160 found Risk assessment for (i) erythromycin A, venlafaxine phototrophic organisms (ii) acetaminophen fish.
Language: Английский