Adherence to the planetary health diet is associated with slower cognitive decline: a prospective cohort analysis of Chinese older adults DOI Creative Commons
Lulu Tang, Xiaoli Yu, Chengxuan Qiu

et al.

International Journal of Behavioral Nutrition and Physical Activity, Journal Year: 2025, Volume and Issue: 22(1)

Published: May 16, 2025

Abstract Background The EAT-Lancet commission has proposed a planetary health reference diet (PHD) aiming to improve human and global environmental sustainability. Emerging evidence suggests that high-quality is modified risk factor cognitive decline. However, population-based in relation the association between this decline scarce. Methods This prospective cohort study examined data from China Health Nutrition Survey (CHNS) during 1997–2011.We included 3404 adults aged 60 years older with normal cognition at baseline. Dietary intake was assessed using 3-day 24 h dietary recalls combined weighing methods function repeated measures of Telephone Interview for Cognitive Status-modified (TICS-m). Planetary Diet Index (PHDI) based on 14 food groups total score 0 140. Higher scores indicated greater adherence PHDI. We used linear mixed model random intercepts slope evaluate PHDI adjusting demographic, health, lifestyle confounders. Results During median follow-up 12 years, higher associated slower memory cognition. Participants highest quintile had significantly (B = 0.025, 95%CI:0.000-0.049, P trend 0.019) 0.020, 95%CI:0.004–0.037, 0.029) compared those lowest quintile. Stratified analyses revealed physical activity these associations ( < 0.05). Among participants engaging vigorous activity, exhibited an attenuated annual 0.070, 95%CI:0.010–0.130, 0.013) 0.045, 95%CI:0.003–0.086, 0.037) Conclusion PHD Chinese adults. Physical particularly may enhance benefits pattern. These findings highlight potential dual sustainable patterns both health.

Language: Английский

Associations between the EAT-Lancet planetary health diet and incident dementia DOI Creative Commons
Jessica Samuelsson,

Isabelle Glans,

Anna Stubbendorff

et al.

The Journal of Prevention of Alzheimer s Disease, Journal Year: 2025, Volume and Issue: unknown, P. 100166 - 100166

Published: April 1, 2025

Language: Английский

Citations

0
Plasma Metabolite Profiles Linked to EAT‐Lancet Diet and Risk of Inflammatory Bowel Disease: A Prospective Cohort Study From UK Biobank DOI
Xiaohua Ye,

Chunmin Lou,

Zhe Shen

et al.

Molecular Nutrition & Food Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 13, 2025

ABSTRACT The EAT‐Lancet Commission recommends a sustainable, health‐focused diet, but its impact on inflammatory bowel disease (IBD) and metabolic mechanisms remains unclear. This study explores the association between diet IBD risk. We included 187 558 participants from UK Biobank, free at baseline. Dietary intake was assessed using validated 24‐h dietary recall, an score calculated. Incident cases were identified through primary care, hospital data, death registries. Cox proportional hazards models used to estimate hazard ratios (HRs) 95% confidence intervals (CIs). Over mean follow‐up of 13.15 years, 571 Crohn's (CD) 1066 ulcerative colitis (UC) recorded. HRs per 1‐point increase in 0.95 (95% CI: 0.91–0.98) for IBD, 0.91–1.00) UC, 0.93 0.87–0.98) CD. Seven metabolites as mediators, accounting 10.7% association. Greater adherence associated with trend toward reduced risk, mediating this These findings emphasize nutritional relevance reducing

Language: Английский

Citations

0
Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications DOI Open Access
Mónika Fekete, Andrea Ceglédi,

Ágnes Szappanos

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(8), P. 1351 - 1351

Published: April 15, 2025

Vitamin D plays a crucial role in the regulation of immune system, with immunomodulatory effects that are key prevention colorectal cancer (CRC). Over past decades, research has shown this steroid hormone impacts much more than bone health, significantly influencing responses. enhances organ functions such as spleen and lymph nodes, boosts T-cell activity, which is essential defending body against tumors. Additionally, vitamin mitigates inflammatory responses closely linked to development, reducing inflammation contributes CRC. It acts via receptors (VDRs) expressed on cells, modulating Adequate levels influence gene expression related cell proliferation, inhibiting tumor development. also activates mechanisms suppress survival, migration, metastasis. Low have been associated an increased risk CRC, deficiency correlating higher disease incidence. Lifestyle factors, diet high red meat calories but low fiber, fruits, vegetables, well physical inactivity, contribute CRC risk. Insufficient calcium intake occurrence poorer clinical outcomes. Maintaining optimal adequate dietary preventing improving patient prognosis. This review explores summarizes findings from randomized trials assessing supplementation

Language: Английский

Citations

0
Adherence to the planetary health diet is associated with slower cognitive decline: a prospective cohort analysis of Chinese older adults DOI Creative Commons
Lulu Tang, Xiaoli Yu, Chengxuan Qiu

et al.

International Journal of Behavioral Nutrition and Physical Activity, Journal Year: 2025, Volume and Issue: 22(1)

Published: May 16, 2025

Abstract Background The EAT-Lancet commission has proposed a planetary health reference diet (PHD) aiming to improve human and global environmental sustainability. Emerging evidence suggests that high-quality is modified risk factor cognitive decline. However, population-based in relation the association between this decline scarce. Methods This prospective cohort study examined data from China Health Nutrition Survey (CHNS) during 1997–2011.We included 3404 adults aged 60 years older with normal cognition at baseline. Dietary intake was assessed using 3-day 24 h dietary recalls combined weighing methods function repeated measures of Telephone Interview for Cognitive Status-modified (TICS-m). Planetary Diet Index (PHDI) based on 14 food groups total score 0 140. Higher scores indicated greater adherence PHDI. We used linear mixed model random intercepts slope evaluate PHDI adjusting demographic, health, lifestyle confounders. Results During median follow-up 12 years, higher associated slower memory cognition. Participants highest quintile had significantly (B = 0.025, 95%CI:0.000-0.049, P trend 0.019) 0.020, 95%CI:0.004–0.037, 0.029) compared those lowest quintile. Stratified analyses revealed physical activity these associations ( < 0.05). Among participants engaging vigorous activity, exhibited an attenuated annual 0.070, 95%CI:0.010–0.130, 0.013) 0.045, 95%CI:0.003–0.086, 0.037) Conclusion PHD Chinese adults. Physical particularly may enhance benefits pattern. These findings highlight potential dual sustainable patterns both health.

Language: Английский

Citations

0