Enantioselective α-C(sp3)–H Borylation of Masked Primary Alcohols Enabled by Iridium Catalysis DOI
Qian Gao, Yinwu Li, Lili Chen

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

Functional group-directed site- and enantioselective C(sp3)–H functionalization of alcohols or masked represents a formidable challenge. We herein report the first example iridium-catalyzed asymmetric α-C(sp3)–H borylation primary alcohol-derived carbamates by judicious choice directing groups. A variety chiral borylated were obtained with good to high enantioselectivities. also demonstrated synthetic utility taking advantage highly transformable feature C–B bonds leaving ability carbamates.

Language: Английский

Ir-Catalyzed, Nitrogen-Directed C(sp3)–H and C(sp2)–H Borylation with a Spiro-Fluorene-Indenoindenyl Ligand DOI Creative Commons

Tomonori Inoue,

Yu Sato, Yuki Nagashima

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 4061 - 4068

Published: Feb. 21, 2025

Language: Английский

Citations

1
Bis-CF3-bipyridine Ligands for the Iridium-Catalyzed Borylation of N-Methylamides DOI
Daniel Marcos‐Atanes, Gonzalo Jiménez‐Osés, José L. Mascareñas

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 7112 - 7120

Published: April 16, 2025

Language: Английский

Citations

0
Enantioselective α-C(sp3)–H Borylation of Masked Primary Alcohols Enabled by Iridium Catalysis DOI
Qian Gao, Yinwu Li, Lili Chen

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

Functional group-directed site- and enantioselective C(sp3)–H functionalization of alcohols or masked represents a formidable challenge. We herein report the first example iridium-catalyzed asymmetric α-C(sp3)–H borylation primary alcohol-derived carbamates by judicious choice directing groups. A variety chiral borylated were obtained with good to high enantioselectivities. also demonstrated synthetic utility taking advantage highly transformable feature C–B bonds leaving ability carbamates.

Language: Английский

Citations

1