The microbiome’s influence on obesity: mechanisms and therapeutic potential DOI
Dawit Adisu Tadese, James Mwangi, Lei Luo

et al.

Science China Life Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 28, 2024

Language: Английский

Neurodegenerative diseases and catechins: (−)-epigallocatechin-3-gallate is a modulator of chronic neuroinflammation and oxidative stress DOI Creative Commons
Siying Li,

Zaoyi Wang,

Gang Liu

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Aug. 1, 2024

Catechins, a class of phytochemicals found in various fruits and tea leaves, have garnered attention for their diverse health-promoting properties, including potential combating neurodegenerative diseases. Among these catechins, (-)-epigallocatechin-3-gallate (EGCG), the most abundant polyphenol green tea, has emerged as promising therapeutic agent due to its potent antioxidant anti-inflammatory effects. Chronic neuroinflammation oxidative stress are key pathological mechanisms diseases such Alzheimer's disease (AD) Parkinson's (PD). EGCG neuroprotective efficacy scavenging free radicals, reducing attenuating neuroinflammatory processes. This review discusses molecular EGCG's anti-oxidative chronic neuroinflammation, emphasizing effects on autoimmune responses, neuroimmune system interactions, focusing related AD PD. By elucidating action impact processes, this underscores intervention AD, PD, possibly other Overall, emerges natural compound stress, offering novel avenues strategies treatment disorders.

Language: Английский

Citations

12
Progress on the mechanism of intestinal microbiota against colorectal cancer DOI Creative Commons
Guoqiang Xing,

Yu Cui,

Zhiyue Guo

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2025, Volume and Issue: 15

Published: April 28, 2025

The intestinal microbiota plays a crucial role in the occurrence and development of colorectal cancer, its anti - cancer mechanism has become research hotspot. This article comprehensively expounds on molecular mechanisms including aspects such as immune regulation, activation carcinogenic signaling pathways (it should be noted that it is more reasonable to "inhibition pathways"), metabolite mediated effects, maintenance barrier function. At same time, explores roles potential intervention methods probiotic supplementation therapy, immunotherapy, fecal transplantation. In addition, analyzes impact flora therapeutic efficacy cancer. existing results are summarized, future directions prospected, with aim providing new theoretical bases treatment ideas for prevention

Language: Английский

Citations

0
The causal relationship between the human gut microbiota and pyogenic arthritis: a Mendelian randomization study DOI Creative Commons

Boliang Bai,

Longfei Luo,

Feng Yao

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: Nov. 26, 2024

Recent studies have indicated the role of gut microbiota in progression osteoarticular diseases, however, causal relationship between and pyogenic arthritis remains unclear. There is also a lack theoretical basis for application treatment arthritis.

Language: Английский

Citations

1
Effects of Dietary Supplementation of Zinc Oxide Quantum Dots on Growth Performance and Gut Health in Broilers DOI
Lei Shi,

Meng-Ling Ruan,

Bingbing Zhang

et al.

Biological Trace Element Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Language: Английский

Citations

0
The microbiome’s influence on obesity: mechanisms and therapeutic potential DOI
Dawit Adisu Tadese, James Mwangi, Lei Luo

et al.

Science China Life Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 28, 2024

Language: Английский

Citations

0