Advances in gut-lung axis research: clinical perspectives on pneumonia prevention and treatment DOI Creative Commons
Fang Ye, Linnan Li, Jiao Wang

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 22, 2025

In recent years, the study of interaction between gut microbiota and distant organs such as heart, lungs, brain, liver has become a hot topic in field microbiology. With deeper understanding its immune regulation mechanisms action, these findings have increasingly highlighted their guiding value clinical practice. The is not only largest digestive organ human body but also habitat for most microorganisms. Imbalances microbial communities been associated with various lung diseases, allergic asthma cystic fibrosis. Furthermore, significant impacts on metabolic function responses. Their metabolites regulate gastrointestinal systems may affect lungs brain. As one common types respiratory system diseases worldwide, pulmonary infections high morbidity mortality rates. Pulmonary caused by dysfunction can lead to problems like diarrhea, further resulting imbalances within complex interactions that are abnormal manifestations under disequilibrium conditions. Meanwhile, interventions significantly modulate composition microbiota, alteration subsequently indicate susceptibility even contribute prevention or progression. This review delves into infections, elucidating latest advancements gut-lung axis research providing fresh perspective treatment pneumonia.

Language: Английский

Advances in gut-lung axis research: clinical perspectives on pneumonia prevention and treatment DOI Creative Commons
Fang Ye, Linnan Li, Jiao Wang

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 22, 2025

In recent years, the study of interaction between gut microbiota and distant organs such as heart, lungs, brain, liver has become a hot topic in field microbiology. With deeper understanding its immune regulation mechanisms action, these findings have increasingly highlighted their guiding value clinical practice. The is not only largest digestive organ human body but also habitat for most microorganisms. Imbalances microbial communities been associated with various lung diseases, allergic asthma cystic fibrosis. Furthermore, significant impacts on metabolic function responses. Their metabolites regulate gastrointestinal systems may affect lungs brain. As one common types respiratory system diseases worldwide, pulmonary infections high morbidity mortality rates. Pulmonary caused by dysfunction can lead to problems like diarrhea, further resulting imbalances within complex interactions that are abnormal manifestations under disequilibrium conditions. Meanwhile, interventions significantly modulate composition microbiota, alteration subsequently indicate susceptibility even contribute prevention or progression. This review delves into infections, elucidating latest advancements gut-lung axis research providing fresh perspective treatment pneumonia.

Language: Английский

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