An Optimized Graphene-Based Surface Plasmon Resonance Biosensor for Detecting SARS-CoV-2 DOI Creative Commons
Talía Tene, Fabian Arias Arias, Karina I. Paredes-Páliz

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(22), P. 10724 - 10724

Published: Nov. 19, 2024

Graphene-enhanced surface plasmon resonance (SPR) biosensors offer promising advancements in viral detection, particularly for SARS-CoV-2. This study presents the design and optimization of a multilayer SPR biosensor incorporating silver, silicon nitride, single-layer graphene, thiol-tethered ssDNA to achieve high sensitivity specificity. Key metrics, including angle shift (Δθ), (S), detection accuracy (DA), figure merit (FoM), were assessed across SARS-CoV-2 concentrations from 150 525 mM. The optimized achieved 315.91°/RIU at 275 mM maximum Δθ 4.2° 400 mM, demonstrating strong responsiveness virus binding. sensor maintained optimal lower concentrations, with linear response up after which saturation limited further responsiveness. These results highlight suitability real-time, point-of-care low loads, supporting its potential early diagnostics epidemiological monitoring.

Language: Английский

Metasurface Based Surface Plasmon Resonance (SPR) Biosensor for Cervical Cancer Detection with Behaviour Prediction using Machine Learning Optimization Based on Support Vector Regression DOI
Jacob Wekalao,

Mouleeswaran Singanallur Kumaresan,

Srinivasan Mallan

et al.

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 28, 2024

Language: Английский

Citations

19
Graphene-Based SPR Sensor Design for Bio-Alcohol Detection in the Terahertz Regime with Machine Learning Optimization Using XGBoost Regressor DOI
Jacob Wekalao, Shobhit K. Patel, P Ashok

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 10, 2025

Language: Английский

Citations

18
Graphene Metasurface Based Biosensor for COVID-19 Detection in the Terahertz Regime with Machine Learning Optimization using K-Nearest Neighbours Regression DOI
Jacob Wekalao,

Ngaira Mandela,

Arun Kumar S

et al.

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 2, 2024

Language: Английский

Citations

17
Terahertz metasurface biosensor for high-sensitivity salinity detection and data encoding with machine learning optimization based on random forest regression DOI
Jacob Wekalao,

Ngaira Mandela

Optical and Quantum Electronics, Journal Year: 2024, Volume and Issue: 56(11)

Published: Nov. 4, 2024

Language: Английский

Citations

16
Graphene-Enabled Multiresonator Metasurfaces for Ultrasensitive Surface Plasmon Resonance Detection of Waterborne Bacteria Across Multiple Frequencies with Machine Learning Optimization DOI
Jacob Wekalao, Shobhit K. Patel, A. M. Balamurugan

et al.

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 21, 2024

Language: Английский

Citations

16
Machine learning optimized design of THz piezoelectric perovskite-based biosensor for the detection of formalin in aqueous environments DOI Creative Commons
Jacob Wekalao, Shobhit K. Patel,

Om Prakash Kumar

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 6, 2025

Language: Английский

Citations

13
Ultra-sensitive Terahertz Hemoglobin Detection Using Graphene-Enhanced Metasurface Surface Plasmon Resonance Biosensors Optimized with K-Nearest Neighbors Regression Machine Learning DOI
Jacob Wekalao,

Ngaira Mandela,

Gideon Mwendwa

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Language: Английский

Citations

13
Machine Learning Optimized Optical Surface Plasmon Resonance Biosensor Using Locally Weighted Linear Regression for Rapid and Accurate Detection of Tuberculosis Biomarkers DOI
Basim Ahmad Alabsi, Jacob Wekalao,

Raman Dhivya

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 8, 2025

Language: Английский

Citations

11
Graphene-Enhanced Terahertz Metamaterial Biosensor for Tuberculosis Detection with XGBoost-Based Machine Learning Optimization DOI
Jacob Wekalao

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Language: Английский

Citations

10
Graphene Metasurface-Based Surface Plasmon Resonance Biosensor for Rapid COVID-19 Detection with Machine Learning Optimization DOI
Jacob Wekalao

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Language: Английский

Citations

8