Understanding quality of life in Danish women with metastatic breast cancer undergoing multiple treatments

Acta Oncologica, Journal Year: 2025, Volume and Issue: 64, P. 292 - 302

Published: Feb. 23, 2025

Background: Women with metastatic breast cancer (mBC) may experience several symptoms exacerbated by successive treatments. There is however, a lack of knowledge the most important and how these affect daily life function. This study aims to elucidate quality (QoL), including both functions, among mBC women undergoing varied Methodology: We conducted cross-sectional electronic questionnaire enrolling (≥ stage III) receiving medical treatment through September–December 2023. QoL, symptoms, function were measured using European Organization for Research Treatment Cancer (EORTC) core (QLQ-C30) module (BR45). Health-related (HRQoL), defined EORTC, covers subjective perceptions positive negative aspects patients’ physical, emotional, social, cognitive functions. examined associations between line therapy types, estimated odds ratios (ORs) confidence intervals (CIs). Results: Of 359 eligible participants, 111 responded (30.9%). At commencement, 90.9% participants received at least one type systemic treatment, 16.2% chemotherapy, 61.3% anti-hormonal 66.6% targeted treatment. QLQ-C30 sum scores highest in (80.7, interquartile range [IQR]: 17.6), followed (78.8, IQR: 18.4), lowest chemotherapy (77.1, 24.8). Quality decreased subsequent lines (first line: 80.3, 20.7, fourth 67.4, 11.3). No significant differences found functions or individual according monotherapy type. Interpretation: substantial symptom burden reduced functioning, their QoL differs underlines that living need support effective management maintain QoL.

Language: Английский

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Survivorship Care for People Affected by Advanced or Metastatic Cancer: Building on the Recent Multinational Association of Supportive Care in Cancer-ASCO Standards and Practice Recommendations

American Society of Clinical Oncology Educational Book, Journal Year: 2025, Volume and Issue: 45(3)

Published: April 14, 2025

Although there is a growing number of people living with advanced or metastatic cancer, primarily because more effective treatment regimens, are limited estimates the actual cancer. Many will have treatable but not curable cancers, may survival measured in years, and periods on off therapy. People disease, as well their families caregivers, experience significant unmet needs, overlapping yet distinct to those potentially Recently, Multinational Association Supportive Care Cancer ASCO developed standards practice recommendations relevant delivery quality survivorship care for The included seven domains: (1) person-centered care; (2) coordinated integrated (3) evidence-based comprehensive (4) evaluated communicated (5) accessible equitable (6) sustainable resourced (7) research data-driven care. Immediate priorities improve clinical include focusing discussions regarding prognosis goals routinely assessing physical, psychological, social needs referral appropriate supportive services; creating blended models care, incorporating elements palliative services. Additional areas focus advocacy policy; system design health delivery; defining, measuring, managing quality; addressing inequity; specifically focused these cancer populations.

Language: Английский

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Cognitive Symptoms Across Diverse Cancers

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(8), P. e2430833 - e2430833

Published: Aug. 28, 2024

Psychosocial health services for adults with cancer should include support cognitive symptoms and symptom clusters.

Language: Английский

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Delivering improved survivorship care for people affected by advanced or metastatic cancer

Acta Oncologica, Journal Year: 2024, Volume and Issue: 63, P. 939 - 942

Published: Dec. 9, 2024

Language: Английский

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