Osteoporosis as a Potential Modifiable Risk Factor for Dementia in Thailand: A Cross-Sectional Analysis DOI Open Access

Parit Hiri-O-tappa,

Kasidid Lawongsa,

Supatcha Kengpanich

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: June 30, 2024

Objective: This study aims to explore the potential of osteoporosis as a modifiable risk factor for dementia and investigate whether treatments like estrogen supplementation bisphosphonates can reduce in Thai population. aimed evaluate patients with osteoporosis. Materials methods: A cross-sectional analysis was conducted. Participants aged <50 years those history at baseline were excluded. Clinical variables analyzed using chi-squared test. Logistic regression conducted determine independent factors after adjusting confounders. Results: The cohort on 54,399 participants, whom 9763 (17.9%) had results indicated that individuals an odds ratio (OR) 1.62-fold higher developing compared without (95% confidence interval (CI) 1.37-1.92, p-value < 0.001). Furthermore, not undergoing any treatment, receiving bisphosphonate treatment showed reduced associations dementia, OR 0.84 CI 0.73-0.98, = 0.023) 0.66 0.60-0.73, 0.001), respectively. Conclusion: findings suggest elevated contribute substantially our understanding link between

Language: Английский

The Use of Artificial Intelligence in Writing Scientific Review Articles DOI Creative Commons
Melissa A. Kacena, Lilian I. Plotkin, Jill C. Fehrenbacher

et al.

Current Osteoporosis Reports, Journal Year: 2024, Volume and Issue: 22(1), P. 115 - 121

Published: Jan. 16, 2024

Abstract Purpose of Review With the recent explosion in use artificial intelligence (AI) and specifically ChatGPT, we sought to determine whether ChatGPT could be used assist writing credible, peer-reviewed, scientific review articles. We also assess, a study, advantages limitations using for this purpose. To accomplish this, 3 topics importance musculoskeletal research were selected: (1) intersection Alzheimer’s disease bone; (2) neural regulation fracture healing; (3) COVID-19 health. For each these topics, approaches write manuscript drafts undertaken: human only; only (AI-only); combination approach #1 #2 (AI-assisted). Articles extensively fact checked edited ensure quality, resulting final manuscripts that significantly different from original drafts. Numerous parameters measured throughout process quantitate disadvantages approaches. Recent Findings Overall, AI decreased time spent article, but required more extensive checking. AI-only approach, up 70% references cited found inaccurate. Interestingly, AI-assisted resulted highest similarity indices suggesting higher likelihood plagiarism. Finally, although technology is rapidly changing, at 4.0 had cutoff date September 2021 rendering identification articles impossible. Therefore, all literature published past was manually provided #3 identical contemporary citations. As result, health topic, abandoned midstream due overlap with #3. Summary The main objective study see scientifically appropriate manner improve process. Indeed, reduced significant inaccuracies. latter necessitates cannot currently alone careful oversight by humans

Language: Английский

Citations

75
The Utility of AI in Writing a Scientific Review Article on the Impacts of COVID-19 on Musculoskeletal Health DOI Creative Commons

Olatundun D. Awosanya,

Alexander Harris,

Amy Creecy

et al.

Current Osteoporosis Reports, Journal Year: 2024, Volume and Issue: 22(1), P. 146 - 151

Published: Jan. 13, 2024

Abstract Purpose of Review There were two primary purposes to our reviews. First, provide an update the scientific community about impacts COVID-19 on musculoskeletal health. Second, was determine value using a large language model, ChatGPT 4.0, in process writing review article. To accomplish these objectives, we originally set out write three articles topic different methods produce initial drafts articles. The first article written traditional manner by humans, second be exclusively (AI-only or AIO), and third approach input outline references selected humans from 1 into ChatGPT, AI assist completing (AI-assisted AIA). All extensively fact-checked edited all co-authors leading final manuscripts, which significantly drafts. Recent Findings Unfortunately, during this process, it became clear that 2 not feasible for very recent like as at time, 4.0 had cutoff date September 2021 published after provided making approaches 3 virtually identical. Therefore, only (human AI-assisted). Here found human-only took less time complete than AI-assisted approach. This largely due number hours required fact-check edit manuscript. Of note, resulted inaccurate attributions (about 20%) higher similarity index suggesting increased risk plagiarism. Summary main aim project whether use could improve Based experience, with current state technology, would advised solely article, especially topic.

Language: Английский

Citations

16
Bioactive hydrogel formulations for regeneration of pathological bone defects DOI
Zuhao Li, Kaixuan Ren, Jiajia Chen

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 380, P. 686 - 714

Published: Feb. 17, 2025

Language: Английский

Citations

2
Using AI to Write a Review Article Examining the Role of the Nervous System on Skeletal Homeostasis and Fracture Healing DOI Creative Commons
Murad K. Nazzal, Ashlyn J. Morris,

Reginald S. Parker

et al.

Current Osteoporosis Reports, Journal Year: 2024, Volume and Issue: 22(1), P. 217 - 221

Published: Jan. 13, 2024

Three review articles have been written that discuss the roles of central and peripheral nervous systems in fracture healing. While content among is overlapping, there a key difference between them: use artificial intelligence (AI). In one paper, first draft was solely by humans. second AI using ChatGPT 4.0 (AI-only or AIO). third but literature references were supplied from human-written paper (AI-assisted AIA). This project done to evaluate capacity conduct scientific writing. Importantly, all manuscripts fact checked extensively edited co-authors rendering final manuscript drafts significantly different drafts.

Language: Английский

Citations

15
Use of AI Language Engine ChatGPT 4.0 to Write a Scientific Review Article Examining the Intersection of Alzheimer’s Disease and Bone DOI Creative Commons
Tyler J. Margetts, Sonali Karnik,

Hannah S. Wang

et al.

Current Osteoporosis Reports, Journal Year: 2024, Volume and Issue: 22(1), P. 177 - 181

Published: Jan. 16, 2024

Abstract Purpose of Review This Comment represents three review articles on the relationship between Alzheimer’s disease, osteoporosis, and fracture in an exploration benefits that AI can provide scientific writing. The first drafts were written (1) entirely by humans; (2) ChatGPT 4.0 (AI-only or AIO); (3) humans whereby selected literature references, but completed writing (AI-assisted AIA). Importantly, each article was edited carefully checked for accuracy all co-authors resulting a final manuscript which significantly different from original draft. Recent Findings human-written took most time start to finish, AI-only least time, AI-assisted fell two. When comparing drafts, had higher percentages text than human article. paper percentage incorrect references draft paper. similarity score other two when examined plagiarism identification software. Summary experiment used tracking, editing, comparison software examine risks using assist It showed while may reduce total hallucinations prevalent issues with this method editing still necessary ensure accuracy.

Language: Английский

Citations

12
The potential link between the development of Alzheimer’s disease and osteoporosis DOI Creative Commons

Fariha Nasme,

Jyotirmaya Behera,

Prisha Tyagi

et al.

Biogerontology, Journal Year: 2025, Volume and Issue: 26(1)

Published: Jan. 20, 2025

Language: Английский

Citations

0
Scoping review exploring the impact of hip fracture in older adults with cognitive impairment or dementia DOI Creative Commons
Hajar Abu Alrob,

Vehra Muhammad Afeef,

Abdallah Shurman

et al.

BMJ Open, Journal Year: 2025, Volume and Issue: 15(4), P. e093893 - e093893

Published: April 1, 2025

Objectives This review summarises the impact of hip fractures on health outcomes including subsequent falls, hospitalisation, length hospital stay (LOS), functional status, quality life and mortality in older adults with cognitive impairment or dementia. It also explores risk institutionalisation following a fracture this population. Design A scoping Arksey O’Malley framework guided by Joanna Briggs Institute methodology adheres to Preferred Reporting Items for Systematic Reviews Meta-analyses extension Scoping guidelines. Data sources comprehensive search strategy was developed MEDLINE, EMBASE, CINAHL grey literature, additional references identified through citation searching Web Science. Eligibility criteria Studies were included if they examined dementia who experienced reported related life, institutionalisation. extraction synthesis Study selection data conducted independently two reviewers using Covidence software. narrative approach employed summarise findings identify key themes, patterns gaps literature. Results We 30 studies reporting fracture. Overall, indicated that individuals have higher hospitalisation rates, poorer walking ability outcomes, as well reduced posthip The LOS inconsistent across studies, some shorter others indicating longer LOS. Individuals consistently exhibit rates at days, 90 days 1-year postfracture compared those without found 21 evaluated Older significantly more likely be institutionalised fracture, nearly five times failing return home increased persists up is particularly pronounced severe impairment, nursing placement observed among fractures. Conclusion experience worse fractures, mortality, postfracture. Future research should focus developing effective strategies prevention, optimising osteoporosis treatment high-risk population, targeted interventions improve reduce vulnerable

Language: Английский

Citations

0
Connecting the dots: sex, depression, and musculoskeletal health DOI Creative Commons

Mackenzie Newman,

Henry J. Donahue, Gretchen N. Neigh

et al.

Journal of Clinical Investigation, Journal Year: 2024, Volume and Issue: 134(18)

Published: Sept. 16, 2024

Depression and multiple musculoskeletal disorders are overrepresented in women compared with men. Given that depression is a modifiable risk factor improvement of depressive symptoms increases positive outcomes following orthopedic intervention, efforts to improve clinical recognition increased action toward ameliorating among patients positioned reduce complications positively affect patient-reported outcomes. Although psychosocial factors play role the manifestation remittance depression, it also well appreciated primary biochemical changes capable causing perpetuating depression. Unique insight for novel treatments may be facilitated by query bidirectional relationship between health This Review aims synthesize diverse literature on sex, orthopedics emphasize potential common underlying biological substrates. overrepresentation women, emphasis drivers co-occurrence these women's health.

Language: Английский

Citations

1
Rationale of Medication Choices in Patients With Alzheimer Disease DOI
Khui Wei Wee,

Kah Cheong Tong

Journal of the American Medical Directors Association, Journal Year: 2024, Volume and Issue: 25(8), P. 105104 - 105104

Published: June 19, 2024

Language: Английский

Citations

0
Osteoporosis as a Potential Modifiable Risk Factor for Dementia in Thailand: A Cross-Sectional Analysis DOI Open Access

Parit Hiri-O-tappa,

Kasidid Lawongsa,

Supatcha Kengpanich

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: June 30, 2024

Objective: This study aims to explore the potential of osteoporosis as a modifiable risk factor for dementia and investigate whether treatments like estrogen supplementation bisphosphonates can reduce in Thai population. aimed evaluate patients with osteoporosis. Materials methods: A cross-sectional analysis was conducted. Participants aged <50 years those history at baseline were excluded. Clinical variables analyzed using chi-squared test. Logistic regression conducted determine independent factors after adjusting confounders. Results: The cohort on 54,399 participants, whom 9763 (17.9%) had results indicated that individuals an odds ratio (OR) 1.62-fold higher developing compared without (95% confidence interval (CI) 1.37-1.92, p-value < 0.001). Furthermore, not undergoing any treatment, receiving bisphosphonate treatment showed reduced associations dementia, OR 0.84 CI 0.73-0.98, = 0.023) 0.66 0.60-0.73, 0.001), respectively. Conclusion: findings suggest elevated contribute substantially our understanding link between

Language: Английский

Citations

0