Research progress of nanoparticles in diagnosis and treatment of hepatocellular carcinoma DOI Creative Commons

Lijun Xing,

Yun Chen, Tingting Zheng

et al.

Open Life Sciences, Journal Year: 2024, Volume and Issue: 19(1)

Published: Jan. 1, 2024

Abstract Hepatocellular carcinoma (HCC) is among the most common malignant liver tumors. Despite progress in anticancer drugs and surgical approaches, early detection of HCC remains challenging, often leading to late-stage diagnosis where rapid disease progression precludes intervention, leaving chemotherapy as only option. However, systemic toxicity, low bioavailability, significant adverse effects lead resistance, rendering treatments ineffective for many patients. This article outlines how nanoparticles, following functional modification, offer high sensitivity, reduced drug extended duration action, enabling precise targeting tissues. Combined with other therapeutic modalities imaging techniques, this significantly enhances diagnosis, treatment, long-term prognosis HCC. The advent nanomedicine provides new methodologies strategies integrated treatment

Language: Английский

Research progress of nanoparticles in diagnosis and treatment of hepatocellular carcinoma DOI Creative Commons

Lijun Xing,

Yun Chen, Tingting Zheng

et al.

Open Life Sciences, Journal Year: 2024, Volume and Issue: 19(1)

Published: Jan. 1, 2024

Abstract Hepatocellular carcinoma (HCC) is among the most common malignant liver tumors. Despite progress in anticancer drugs and surgical approaches, early detection of HCC remains challenging, often leading to late-stage diagnosis where rapid disease progression precludes intervention, leaving chemotherapy as only option. However, systemic toxicity, low bioavailability, significant adverse effects lead resistance, rendering treatments ineffective for many patients. This article outlines how nanoparticles, following functional modification, offer high sensitivity, reduced drug extended duration action, enabling precise targeting tissues. Combined with other therapeutic modalities imaging techniques, this significantly enhances diagnosis, treatment, long-term prognosis HCC. The advent nanomedicine provides new methodologies strategies integrated treatment

Language: Английский

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