Olfactory Impairment and Recovery in Zebrafish (Danio rerio) Following Cadmium Exposure DOI Creative Commons
Chiara Maria Motta, Rosa Carotenuto, Chiara Fogliano

et al.

Biology, Journal Year: 2025, Volume and Issue: 14(1), P. 77 - 77

Published: Jan. 15, 2025

Anthropic activities have significantly elevated cadmium levels, making it a significant stressor in aquatic ecosystems. Present high concentrations across water bodies, is known to bioaccumulate and biomagnify throughout the food chain. While toxic effects of on organs tissues species are well-documented, little about its impact sensory systems crucial for survival. Consequently, this study investigated short-term exposure (96 h) 25 µM chloride olfactory system adult zebrafish. The research aimed assess structural functional changes zebrafish's lamellae, providing deeper understanding how affects sense smell species. After exposure, cyto-anatomical alterations lamellae were analysed using light microscopy immunocytochemistry. They revealed severe lamellar edema, epithelial thickening, an increased number apoptotic crypt cells. Rodlet goblet cells also by 3.5- 2.5-fold, respectively, compared control collagen density lamina propria 1.7-fold. Cadmium upregulated metallothioneins PCNA-positive function was assessed through behavioural odour recognition test, followed recovery phase which zebrafish exposed placed clean six days. fish performed poorly, failing reach five consecutive trials. However, damage reduced after period, their performance improved, becoming comparable group. These results suggest that disrupts smell, possible exposure. This evidence sheds aspects animal survival often overlooked when assessing environmental pollution.

Language: Английский

Olfactory Impairment and Recovery in Zebrafish (Danio rerio) Following Cadmium Exposure DOI Creative Commons
Chiara Maria Motta, Rosa Carotenuto, Chiara Fogliano

et al.

Biology, Journal Year: 2025, Volume and Issue: 14(1), P. 77 - 77

Published: Jan. 15, 2025

Anthropic activities have significantly elevated cadmium levels, making it a significant stressor in aquatic ecosystems. Present high concentrations across water bodies, is known to bioaccumulate and biomagnify throughout the food chain. While toxic effects of on organs tissues species are well-documented, little about its impact sensory systems crucial for survival. Consequently, this study investigated short-term exposure (96 h) 25 µM chloride olfactory system adult zebrafish. The research aimed assess structural functional changes zebrafish's lamellae, providing deeper understanding how affects sense smell species. After exposure, cyto-anatomical alterations lamellae were analysed using light microscopy immunocytochemistry. They revealed severe lamellar edema, epithelial thickening, an increased number apoptotic crypt cells. Rodlet goblet cells also by 3.5- 2.5-fold, respectively, compared control collagen density lamina propria 1.7-fold. Cadmium upregulated metallothioneins PCNA-positive function was assessed through behavioural odour recognition test, followed recovery phase which zebrafish exposed placed clean six days. fish performed poorly, failing reach five consecutive trials. However, damage reduced after period, their performance improved, becoming comparable group. These results suggest that disrupts smell, possible exposure. This evidence sheds aspects animal survival often overlooked when assessing environmental pollution.

Language: Английский

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