Hydroxy-Selenomethionine Supplementation During Gestation and Lactation Improve Reproduction of Sows by Enhancing the Antioxidant Capacity and Immunity Under Heat Stress Conditions

Antioxidants, Journal Year: 2025, Volume and Issue: 14(5), P. 525 - 525

Published: April 27, 2025

The objective of this study was to determine whether hydroxy-selenomethionine (OH-SeMet) exerts better protective effects on sows against heat stress than sodium selenite (SeNa) or seleno-yeast (SeY). A total 60 (Landrace × Yorkshire) were randomly allocated into the three groups and fed a base diet supplemented with SeNa, SeY, OH-SeMet at 0.3 mg Se/kg under condition for reproductive cycle. Compared SeNa could more effectively sustain offspring growth performance, as evidenced by an increased number live-born piglets, higher litter weight day 21, greater body gain from days 1 21. effective in supporting endogenous redox systems, shown enhanced levels TXNRD GSH reduced GSSG serum sows, improved T-AOC, TXNRD, alongside decreased MDA heightened T-AOC jejunum piglets. Furthermore, among two tested organic Se sources, SeY regulating immune responses compared SeNa. inflammation-related markers CRP, HP, MAP, LPS, IL-1β, IL-6, TNF-α, some all which their offspring. In addition, also showed glucose, TG, NEFA levels, along elevated insulin sows. Correspondingly, forms Se, particularly those gut protection sows’ offspring, indicated crypt depth villus height/crypt ratio duodenum, jejunum, ileum Specifically, upregulated expression selenoproteins (GPX6, TXNRD3, GPX4, SELENON), tight junction protein (ZO-1), host defense peptide gene (pBD1, pBD2, pBD3, NPG3, NPG4), downregulating inflammation factor (IL-1β, IL-6 TNF-α) pro-apoptotic (P53) Taken together, mitigated adverse induced

Language: Английский

Organic Trace Minerals Enhance the Gut Health of British Shorthair Cats by Regulating the Structure of Intestinal Microbiota

Metabolites, Journal Year: 2024, Volume and Issue: 14(9), P. 494 - 494

Published: Sept. 11, 2024

Trace minerals are essential for biological processes, including enzyme function, immune response, and hormone synthesis. The study assessed the effects of different dietary trace on gut health, microbiota composition, function cats. Eighteen adult British Shorthair cats were divided into three groups receiving inorganic (ITM), a 50/50 mix organic (ITM + OTM), or (OTM) 28 days. OTM showed enhanced capacities, reduced intestinal barrier lower inflammation condition. altered diversity, with Simpson index higher Shannon (

Language: Английский

Effect of Dietary Sugarcane Bagasse on Reproductive Performance, Constipation, and Gut Microbiota of Gestational Sows

Animals, Journal Year: 2024, Volume and Issue: 14(17), P. 2523 - 2523

Published: Aug. 30, 2024

This experiment aimed to evaluate the effects of using sugarcane bagasse (SB) as a substitute for soybean hulls and wheat bran in diet pregnant sows on their reproductive performance gut microbiota. A total seventy-two primiparous were randomly divided into four treatment groups, with eighteen replicates one sow each. The fed basal supplemented 0% (CON), 5%, 10%, 15% SB replace from day 57 gestation until end period. results showed that contains higher levels crude fiber (42.1%) neutral detergent (81.3%) than hulls, it also exhibited highest volumetric expansion when soaked water (50 g expanding 389.8 mL) compared other six materials we tested (vegetable scraps, bran, rice meal, corn DDGS). Compared CON, 5% significantly increased litter birth weight piglets. Meanwhile, 10% rates constipation reduced contents isobutyric acid isovaleric feces. Furthermore, disturbed microbial diversity increasing

Language: Английский