Latest developments in biomaterial interfaces and drug delivery: challenges, innovations, and future outlook DOI
Saraswati Patel, Samsi D. Salaman, Devesh U. Kapoor

et al.

Zeitschrift für Naturforschung C, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

Abstract An ideal drug carrier system should demonstrate optimal payload and release characteristics, thereby ensuring prolonged therapeutic index while minimizing adverse effects. The field of delivery has undergone significant advancements, particularly within the last two decades, owing to revolutionary impact biomaterials. use biomaterials presents due their biocompatibility biodegradability, which must be addressed in order achieve effective delivery. properties biomaterial its interface are primarily influenced by physicochemical attributes, physiological barriers, cellular trafficking, immunomodulatory By attuning these regulating properties, masking immune system’s response, bio can effectively modulated, leading development innovative supramolecular structures with enhanced effectiveness. With a comprehensive understanding technologies, there is growing demand for repurposing existing drugs new indications this space. This review aims provide substantial body evidence showcasing productiveness delivery, as well methods mitigating modulating barriers along an examination future prospects field.

Language: Английский

Predictive Identification of Oral Cancer Using AI and Machine Learning DOI Creative Commons
Saraswati Patel, Dheeraj Kumar

Oral Oncology Reports, Journal Year: 2024, Volume and Issue: unknown, P. 100697 - 100697

Published: Dec. 1, 2024

Language: Английский

Citations

5
Exploring the application of herbal photosensitizers in antimicrobial photodynamic therapy against Mycobacterium Tuberculosis DOI

Vinny Virdi,

Jagriti Singh, Rolee Sharma

et al.

3 Biotech, Journal Year: 2025, Volume and Issue: 15(2)

Published: Jan. 20, 2025

Language: Английский

Citations

0
Eco-friendly synthesis, structural insights, and antimicrobial potential of 1,3,5-tri-N-substituted hexahydro-1,3,5-triazine derivatives DOI
Jyoti Kumawat, Sonika Jain,

Namita Misra

et al.

Analytical Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 23

Published: March 16, 2025

Language: Английский

Citations

0
Exploring the Therapeutic Potential of 1,3-Benzimidazole: An Auspicious Heterocyclic Framework DOI Open Access
Shivkant Patel, Ashim Kumar Sen, Dhanya B. Sen

et al.

Oriental Journal Of Chemistry, Journal Year: 2025, Volume and Issue: 41(2), P. 330 - 355

Published: April 28, 2025

The scientific study of benzimidazole derivatives has advanced steadily due to its fascinating chemical structure with wide range biological activities. This unique organic nitrogen bridged heterocyclic compounds have found applications in pharmaceuticals, organometallics, and natural products, establishing themselves as indispensable tools for medicinal chemists. To gather insights, comprehensive searches were conducted across databases such Google, PubMed, Scopus, Google Scholar, others. research highlights pharmacological profile 1,3˗Benzimidazole while examining their characteristics therapeutic potential, including antimicrobial, anticancer, antiviral, antidiabetic, antitubercular, antifungal, antimalarial, anti-inflammatory effects. 1,3˗benzimidazole scaffold is a cornerstone numerous pharmaceutical products serves the basis several clinically approved drugs, antihistamine drug lerisetron, antiviral agent maribavir, proton pump inhibitor omeprazole, anthelmintic triclabendazole, Anti˗fungal chlormidazole. Recent developments uses variety domains are explained this thorough study. Furthermore, detailed molecular docking studies included, providing chemists valuable insights robust framework future development efforts.

Language: Английский

Citations

0
Latest developments in biomaterial interfaces and drug delivery: challenges, innovations, and future outlook DOI
Saraswati Patel, Samsi D. Salaman, Devesh U. Kapoor

et al.

Zeitschrift für Naturforschung C, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

Abstract An ideal drug carrier system should demonstrate optimal payload and release characteristics, thereby ensuring prolonged therapeutic index while minimizing adverse effects. The field of delivery has undergone significant advancements, particularly within the last two decades, owing to revolutionary impact biomaterials. use biomaterials presents due their biocompatibility biodegradability, which must be addressed in order achieve effective delivery. properties biomaterial its interface are primarily influenced by physicochemical attributes, physiological barriers, cellular trafficking, immunomodulatory By attuning these regulating properties, masking immune system’s response, bio can effectively modulated, leading development innovative supramolecular structures with enhanced effectiveness. With a comprehensive understanding technologies, there is growing demand for repurposing existing drugs new indications this space. This review aims provide substantial body evidence showcasing productiveness delivery, as well methods mitigating modulating barriers along an examination future prospects field.

Language: Английский

Citations

1