Cardiometabolic index is associated with increased bone mineral density: a population-based cross-sectional study DOI Creative Commons

Xujin Wu,

Xixin Jin,

Wei Xu

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Sept. 18, 2024

Background Osteoporosis is a multifactorial bone disease in which lipid metabolism plays an important role. Bone Mineral Density (BMD) measured by Dual-energy X-ray Absorptiometry (DXA) critical indicator for diagnosing osteoporosis. The cardiometabolic index (CMI) novel metric that combines two quantitative indicators of blood lipids—triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C). This study explores the association between CMI BMD seeks to elucidate role context health. Methods Based on data National Health Nutrition Examination Survey (NHANES) 2017–March 2020-pre-pandemic, weighted multiple linear regression smooth curve fitting were used relationship femoral BMD. Stratified analyses also conducted age, gender, BMI, ethnicity, diabetes hypertension status. And, saturation threshold effect was further analyzed using two-stage model. Result enrolled total 1,650 participants (48.7% males), with average age 63.0 ± 8.6 years. After adjusting confounding factors, positively correlated femur BMD, trochanter intertrochanter while correlation neck not statistically significant. In fully adjusted model, each unit increase associated 0.026 (g/cm 2 ) 0.022 0.034 Subjects highest quartile had 0.035 0.039 fully-adjusted model compared those lowest quartile. addition, observed thresholds 1.073, 1.431 respectively. Conclusion strongly indicating its potential relevance metabolism. However, health, especially regarding osteoporosis risk, requires investigation large-scale prospective studies.

Language: Английский

Comparison of NAFLD, MAFLD And MASLD Prevalence And Clinical Characteristics in Asia Adults DOI
Xinjuan Huang,

Ruoling Yu,

Xinyun Tan

et al.

Journal of Clinical and Experimental Hepatology, Journal Year: 2024, Volume and Issue: 15(1), P. 102420 - 102420

Published: Oct. 8, 2024

Language: Английский

Citations

7
Cardiometabolic index is associated with increased bone mineral density: a population-based cross-sectional study DOI Creative Commons

Xujin Wu,

Xixin Jin,

Wei Xu

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Sept. 18, 2024

Background Osteoporosis is a multifactorial bone disease in which lipid metabolism plays an important role. Bone Mineral Density (BMD) measured by Dual-energy X-ray Absorptiometry (DXA) critical indicator for diagnosing osteoporosis. The cardiometabolic index (CMI) novel metric that combines two quantitative indicators of blood lipids—triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C). This study explores the association between CMI BMD seeks to elucidate role context health. Methods Based on data National Health Nutrition Examination Survey (NHANES) 2017–March 2020-pre-pandemic, weighted multiple linear regression smooth curve fitting were used relationship femoral BMD. Stratified analyses also conducted age, gender, BMI, ethnicity, diabetes hypertension status. And, saturation threshold effect was further analyzed using two-stage model. Result enrolled total 1,650 participants (48.7% males), with average age 63.0 ± 8.6 years. After adjusting confounding factors, positively correlated femur BMD, trochanter intertrochanter while correlation neck not statistically significant. In fully adjusted model, each unit increase associated 0.026 (g/cm 2 ) 0.022 0.034 Subjects highest quartile had 0.035 0.039 fully-adjusted model compared those lowest quartile. addition, observed thresholds 1.073, 1.431 respectively. Conclusion strongly indicating its potential relevance metabolism. However, health, especially regarding osteoporosis risk, requires investigation large-scale prospective studies.

Language: Английский

Citations

3