Management of non-Cardiac Organ Failure in cardiogenic shock

American Heart Journal Plus Cardiology Research and Practice, Journal Year: 2025, Volume and Issue: unknown, P. 100549 - 100549

Published: May 1, 2025

Language: Английский

---

Microbiological features of drowning-associated pneumonia: a systematic review and meta-analysis

Annals of Intensive Care, Journal Year: 2024, Volume and Issue: 14(1)

Published: April 20, 2024

Drowning-associated pneumonia (DAP) is frequent in drowned patients, and possibly increases mortality. A better understanding of the microorganisms causing DAP could improve adequacy empirical antimicrobial therapy. We aimed to describe pooled prevalence DAP, involved, impact on patients.

Language: Английский

---

Carbon dioxide pathophysiology and targets following acute brain injury

Intensive Care Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: May 5, 2025

Language: Английский

---

Plasma phosphorylated tau (p-tau231) and total tau (t-tau) as prognostic markers of neurological outcome after cardiac arrest - a multicentre study

Resuscitation, Journal Year: 2024, Volume and Issue: 206, P. 110450 - 110450

Published: Dec. 3, 2024

Language: Английский

---

Validation of the CREST model and comparison with SCAI shock classification for the prediction of circulatory death in resuscitated out-of-hospital cardiac arrest

European Heart Journal Acute Cardiovascular Care, Journal Year: 2024, Volume and Issue: 13(8), P. 605 - 614

Published: May 28, 2024

We validated the CREST model, a 5 variable score for stratifying risk of circulatory aetiology death (CED) following out-of-hospital cardiac arrest (OHCA) and compared its discrimination with SCAI shock classification. Circulatory occurs in approximately third patients admitted after resuscitated OHCA. There is an urgent need improved stratification patient OHCA on arrival to centre improve selection invasive interventions.

Language: Английский

---

Extracerebral multiple organ dysfunction and interactions with brain injury after cardiac arrest

Resuscitation Plus, Journal Year: 2024, Volume and Issue: 19, P. 100719 - 100719

Published: July 19, 2024

Cardiac arrest and successful resuscitation cause whole-body ischemia reperfusion, leading to brain injury extracerebral multiple organ dysfunction. Brain is the of death long-term disability in resuscitated survivors, was conceptualized treated as an isolated injury, which has neglected brain-visceral crosstalk. Extracerebral dysfunction common significantly associated with mortality poor neurological prognosis after resuscitation. However, detailed description characteristics post-resuscitation lacking, bidirectional interactions between visceral organs need be elucidated explore new treatment for neuroprotection. This review aims describe current concepts post-cardiac specific cardiovascular, respiratory, renal, hepatic, adrenal, gastrointestinal, neurohumoral systems. Additionally, we discuss crosstalk organs, especially focusing on how other factors affect progression. We think that clarifying these profound significance treat patients neural/systemic protection improve outcome.

Language: Английский

---

Paramedicine Literature Search

International Journal of Paramedicine, Journal Year: 2024, Volume and Issue: 6, P. 194 - 249

Published: April 3, 2024

search strategy yielded a total of 1,209 citations and are listed below.

Language: Английский

---

Using machine learning to predict neurologic injury in venovenous extracorporeal membrane oxygenation recipients: An ELSO Registry analysis

JTCVS Open, Journal Year: 2024, Volume and Issue: 21, P. 140 - 167

Published: July 2, 2024

BackgroundVenovenous extracorporeal membrane oxygenation (VV-ECMO) is associated with acute brain injury (ABI), including central nervous system (CNS) ischemia (defined as ischemic stroke or hypoxic-ischemic [HIBI]) and intracranial hemorrhage (ICH). Data on prediction models for neurologic outcomes in VV-ECMO are limited.MethodsWe analyzed adult (age ≥18 years) patients the Extracorporeal Life Support Organization (ELSO) Registry (2009-2021) from 676 centers. ABI was defined CNS ischemia, ICH, death, seizures. 67 variables were extracted, clinical characteristics pre-ECMO/on-ECMO variables. Random forest, CatBoost, LightGBM, XGBoost machine learning (ML) algorithms (10-fold leave-one-out cross-validation) used to predict ABI. Feature importance scores pinpoint most important predicting ABI.ResultsOf 37,473 (median age, 48.1 years; 63% male), 2644 (7.1%) experienced ABI, 610 (2%) 1591 (4%) ICH. The areas under receiver operating characteristic curve ICH 0.70, 0.68, respectively. accuracy, positive predictive value, negative value 85%, 19%, 95%, ML identified higher center volume, pre-ECMO cardiac arrest, ECMO pump flow, elevated on-ECMO serum lactate level risk factors its subtypes.ConclusionsThis largest study of use reported date. Performance suboptimal, likely due lack standardization neuromonitoring/imaging protocols data granularity ELSO Registry. Standardized monitoring imaging needed across centers detect true prevalence

Language: Английский

---

Letter to the editor on “Association between type of index complication and outcomes after noncardiac surgery”

Surgery, Journal Year: 2024, Volume and Issue: 176(5), P. 1552 - 1552

Published: Aug. 12, 2024

Language: Английский

---

Prolonged Monitoring of Brain Electrical Activity in the Intensive Care Unit

Neurologic Clinics, Journal Year: 2024, Volume and Issue: 43(1), P. 31 - 50

Published: Oct. 16, 2024

Language: Английский

---