Monro-Kellie 4.0: moving from intracranial pressure to intracranial dynamics DOI Creative Commons

Sérgio Brasil,

Gustavo Cartaxo Patriota, Daniel Agustín Godoy

et al.

Critical Care, Journal Year: 2025, Volume and Issue: 29(1)

Published: June 5, 2025

Abstract The Monro-Kellie doctrine, introduced in the late 18th century, was a groundbreaking concept aimed at explaining interactions between intracranial volume components. It has since become cornerstone of brain physiology, now recognized as dynamics. Initially, doctrine focused on physiological observations three incompressible components cranial vault: tissue, blood, and cerebrospinal fluid (CSF). Over centuries, advancements neuroscience medical technology have deepened our understanding pressure (ICP) regulation, its pathophysiological implications role neurological disorders. This revisitation examines how impairments cerebrovascular autoregulation, compartmentalization glymphatic system interact severely brain-injured patients, calling for new management strategies when facing these critical situations. Additionally, it reinforces need holistic monitoring approach to improve early diagnostics intervention. evolution ICP assessment significantly shaped trauma, spontaneous bleeding, ischemic stroke, hydrocephalus. With introduction innovative tools such ultrasound, automated pupillometry noninvasive waveform monitoring, is shifting toward more accessible continuous evaluation strategies. review explores blending historical principles with cutting-edge innovations transforming neuromonitoring enhancing patient outcomes care.

Language: Английский

The dawn of noninvasive intracranial compliance waveforms: a call for the B-ICONIC improvement and expansion DOI
Sérgio Brasil, Navaz Karanjia, Fabio Silvio Taccone

et al.

Intensive Care Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: June 3, 2025

Language: Английский

Citations

0
Monro-Kellie 4.0: moving from intracranial pressure to intracranial dynamics DOI Creative Commons

Sérgio Brasil,

Gustavo Cartaxo Patriota, Daniel Agustín Godoy

et al.

Critical Care, Journal Year: 2025, Volume and Issue: 29(1)

Published: June 5, 2025

Abstract The Monro-Kellie doctrine, introduced in the late 18th century, was a groundbreaking concept aimed at explaining interactions between intracranial volume components. It has since become cornerstone of brain physiology, now recognized as dynamics. Initially, doctrine focused on physiological observations three incompressible components cranial vault: tissue, blood, and cerebrospinal fluid (CSF). Over centuries, advancements neuroscience medical technology have deepened our understanding pressure (ICP) regulation, its pathophysiological implications role neurological disorders. This revisitation examines how impairments cerebrovascular autoregulation, compartmentalization glymphatic system interact severely brain-injured patients, calling for new management strategies when facing these critical situations. Additionally, it reinforces need holistic monitoring approach to improve early diagnostics intervention. evolution ICP assessment significantly shaped trauma, spontaneous bleeding, ischemic stroke, hydrocephalus. With introduction innovative tools such ultrasound, automated pupillometry noninvasive waveform monitoring, is shifting toward more accessible continuous evaluation strategies. review explores blending historical principles with cutting-edge innovations transforming neuromonitoring enhancing patient outcomes care.

Language: Английский

Citations

0