Preventive and Therapeutic Effects of Baicalein, Galangin, and Isorhamnetin in Chronic Liver Diseases: A Narrative Review DOI Creative Commons
Giuseppe Guido Maria Scarlata, Israel López,

Maria Luisa Gambardella

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1253 - 1253

Published: March 11, 2025

Chronic liver diseases (CLDs), including fatty disease, fibrosis, and cirrhosis, pose significant global health challenges due to the limitedness of therapeutic options. Flavonoids, a class polyphenolic compounds mainly contained in natural sources foods Mediterranean diet, have emerged as potential candidates for protection their anti-inflammatory, antioxidant, anti-fibrotic properties. Baicalein, derived from Scutellaria baicalensis, exhibits hepatoprotective effects by attenuating oxidative stress, inhibiting fibrogenesis, modulating lipid metabolism. Galangin, flavonoid Alpinia officinarum, has demonstrated anti-inflammatory properties, while isorhamnetin, methylated found various fruits herbs, been shown possess qualities, it reduces stress mitigates inflammation CLDs. This narrative review highlights preventive these three flavonoids, emphasizing role promising agents managing CLDs guiding future research.

Language: Английский

Preventive and Therapeutic Effects of Baicalein, Galangin, and Isorhamnetin in Chronic Liver Diseases: A Narrative Review DOI Creative Commons
Giuseppe Guido Maria Scarlata, Israel López,

Maria Luisa Gambardella

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1253 - 1253

Published: March 11, 2025

Chronic liver diseases (CLDs), including fatty disease, fibrosis, and cirrhosis, pose significant global health challenges due to the limitedness of therapeutic options. Flavonoids, a class polyphenolic compounds mainly contained in natural sources foods Mediterranean diet, have emerged as potential candidates for protection their anti-inflammatory, antioxidant, anti-fibrotic properties. Baicalein, derived from Scutellaria baicalensis, exhibits hepatoprotective effects by attenuating oxidative stress, inhibiting fibrogenesis, modulating lipid metabolism. Galangin, flavonoid Alpinia officinarum, has demonstrated anti-inflammatory properties, while isorhamnetin, methylated found various fruits herbs, been shown possess qualities, it reduces stress mitigates inflammation CLDs. This narrative review highlights preventive these three flavonoids, emphasizing role promising agents managing CLDs guiding future research.

Language: Английский

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