Expert Opinion on Drug Delivery, Journal Year: 2025, Volume and Issue: unknown

Published: May 26, 2025

The nasal administration route has gained peak interest in recent literature and as a noninvasive alternative for efficient drug delivery increasing bioavailability of active substances. Technological challenges arise from the drug's physicochemical properties mucosal barrier which innovative particle engineering techniques must be implemented, such using polymeric nanocarriers. This review deals with importance its connection to micelles period between 2015 - 2025 up date was chosen search original research articles where were applied nasally. first part demonstrates utilization micelles, followed by summary how release permeability can achieved cavity through epithelium. second reviews studies conducted on this matter. could superior perform suitable conventional routes. Multiple have already demonstrated that main advantages lie nose-to-brain pathway, conquered via adequately formulated micelles. As an solution, vaccine is also great potential combining

Language: Английский