Microfluidic Detection Platform for Determination of Ractopamine in Food DOI Creative Commons
Cheng-Xue Yu, Kuan-Hsun Huang, To-Lin Chen

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(10), P. 462 - 462

Published: Sept. 26, 2024

A novel microfluidic ractopamine (RAC) detection platform consisting of a RAC chip and smart analysis device is proposed for the determination concentration in meat samples. This technology utilizes gold nanoparticles (AuNPs) modified with glutamic acid (GLU) polyethyleneimine (PEI) to measure food products. When present, AuNPs aggregate through hydrogen bonding, causing noticeable changes their optical properties, which are detected using self-built UV–visible micro-spectrophotometer. Within range 5 80 ppb, linear relationship exists between absorbance ratio (A693nm/A518nm) (Y) (X), expressed as Y = 0.0054X + 0.4690, high coefficient (R2 0.9943). method exhibits limit 1.0 ppb achieves results within 3 min. The practical utility this assay exemplified evaluation concentrations 50 commercially available variance measured those determined via liquid chromatography–tandem mass spectrometry (LC-MS/MS) less than 8.33%. These underscore viability rapid cost-effective solution ensuring safety regulatory compliance livestock industry.

Language: Английский

Advancements in nanomaterials for nanosensors: a comprehensive review DOI Creative Commons
Moustafa A. Darwish, Walaa Abd‐Elaziem, Ammar H. Elsheikh

et al.

Nanoscale Advances, Journal Year: 2024, Volume and Issue: 6(16), P. 4015 - 4046

Published: Jan. 1, 2024

Nanomaterials (NMs) exhibit unique properties that render them highly suitable for developing sensitive and selective nanosensors across various domains.

Language: Английский

Citations

50
Review—Nanosystems-Enhanced Electrochemical Biosensors for Precision in One Health Management DOI Creative Commons
Harsh Sable, Vaishali Kumar, Vandana Singh

et al.

Journal of The Electrochemical Society, Journal Year: 2024, Volume and Issue: 171(3), P. 037527 - 037527

Published: March 11, 2024

One Health is a comprehensive and cohesive strategy that seeks to effectively manage enhance the well-being of people, animals, ecosystems in sustainable manner. Electrochemical biosensors are indispensable vectors for management, with diverse applications across industrial process control, environmental monitoring, healthcare, microbiology, quality assurance. The integration nanotechnology has propelled innovative sensing algorithms, enhancing efficiency precision biosensors. Nanoscale material amplifies their ability detect molecules single biomolecules nano-biosensors utilizing nanoparticles, nanowires, carbon nanotubes (CNTs), nanorods, quantum dots. Nanomaterials, distinguished by surface functionalities, tunability physical/chemical properties, high detection sensitivity, large area, stability, thermal/electrical conductivity, instrumental architecting nano-biosensors. main limitations current times scalability, cross-sensitivity, complex immobilization pathways, toxicity factor nanosensors, which hazardous ecosystem as well humans. This review explores fundamentals nanotechnology-enabled electrochemical biosensors, encompassing composition, manufacturing materials, applications, highlighting necessity advancing biosensor technology control contamination/human diseases order Health.

Language: Английский

Citations

14
Prospects and challenges of sensor materials: A comprehensive review DOI Creative Commons
Nayem Hossain,

Md Israfil Hossain Rimon,

Mariam Akter Mimona

et al.

e-Prime - Advances in Electrical Engineering Electronics and Energy, Journal Year: 2024, Volume and Issue: 7, P. 100496 - 100496

Published: March 1, 2024

Sensor materials have become more important in several industries as they facilitate the development of advanced sensing technologies modern day. These materials, specifically engineered to transform physical, chemical, or biological stimuli into quantifiable signals, play a crucial role gathering vital data for controlling, monitoring, and making informed decisions. It is essential comprehend obstacles prospects linked sensor given escalating demand systems that are both efficient versatile. The qualities material refer its capacity detect quantify alterations surroundings. properties encompass range approaches, including optical, piezoelectric, capacitive, resistive interactions. Although these utilized various such transportation, medicine, agriculture, industrial operations, environmental persistent issues still related improved reaction speed, selectivity, sensitivity. Nevertheless, outlook seems optimistic, current research advancements anticipated result exhibit enhanced performance, durability, energy economy. Developing nanomaterials sophisticated production processes facilitates potential creating highly selective sensitive sensors with new functionalities. This advancement contributes growth Internet Things (IoT) applications massive collection, leading automation decision-making capabilities. review article examines recent advancements, applications, while also discussing encounter opportunities enable them significantly impact multiple society.

Language: Английский

Citations

9
Application of Nanobiosensor Engineering in the Diagnosis of Neurodegenerative Disorders DOI Creative Commons

Thikra S. Dhahi,

Alaa Kamal Yousif Dafhalla, A. Wesam Al-Mufti

et al.

Results in Engineering, Journal Year: 2024, Volume and Issue: 24, P. 102790 - 102790

Published: Sept. 5, 2024

Language: Английский

Citations

8
Integration of microfluidic chips with biosensors DOI Creative Commons

Masindi Sekhwama,

Kelvin Mpofu,

Sivarasu Sudesh

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 6(9)

Published: Aug. 23, 2024

Abstract The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies counteract risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many have demonstrated beyond limits health care that new advancements are required for early detection diagnosis. rising number diseases has led an increasing demand biosensors quicker utilize in healthcare settings. A incorporated with microfluidic chips offers improved compared traditional or classical biosensors. Microfluidic improve performance allowing automation, mixing, separation, throughput processing, transport analytes desired reactors. a chip sensitivity, easy operation can use small volumes samples process results. effectiveness depends also on materials used its fabrication there which reviewed this work. This paper reviews advantages enhance biosensors, fabricate chips, electrodes into time shortening processing at point service. work not previously addressed other including, integration cell-imprinted polymers sensors delved future outlook.

Language: Английский

Citations

7
A Thorough Review of Emerging Technologies in Micro- and Nanochannel Fabrication: Limitations, Applications, and Comparison DOI Creative Commons

Koosha Karimi,

Ali Fardoost,

Nikhil Mhatre

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(10), P. 1274 - 1274

Published: Oct. 21, 2024

In recent years, the field of micro- and nanochannel fabrication has seen significant advancements driven by need for precision in biomedical, environmental, industrial applications. This review provides a comprehensive analysis emerging technologies, including photolithography, soft lithography, 3D printing, electron-beam lithography (EBL), wet/dry etching, injection molding, focused ion beam (FIB) milling, laser micromachining, micro-milling. Each these methods offers unique advantages terms scalability, precision, cost-effectiveness, enabling creation highly customized structures. Challenges related to resolution, high cost traditional techniques are addressed through innovations such as deep reactive etching (DRIE) multipass paper also explores application potential technologies areas lab-on-a-chip devices, biomedical diagnostics, energy-efficient cooling systems. With continued research technological refinement, poised significantly impact future microfluidic nanofluidic

Language: Английский

Citations

7
Nano biosensors: Classification, electrochemistry, nanostructures, and optical properties DOI Creative Commons
Ahmed Mahdi Rheima, Zainab T. Al‐Sharify, Ameen Alwan Mohaimeed

et al.

Results in Engineering, Journal Year: 2024, Volume and Issue: unknown, P. 103428 - 103428

Published: Nov. 1, 2024

Language: Английский

Citations

6
PCR Independent Strategy-Based Biosensors for RNA Detection DOI Creative Commons
Xinran Li, Haoqian Wang, Xin Qi

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(4), P. 200 - 200

Published: April 18, 2024

RNA is an important information and functional molecule. It can respond to the regulation of life processes also a key molecule in gene expression regulation. Therefore, detection technology has been widely used many fields, especially disease diagnosis, medical research, genetic engineering other fields. However, current RT-qPCR for complex, costly requires support professional technicians, resulting it not having great potential rapid application field. PCR-free techniques are most attractive alternative. They low-cost, simple operation method do require large instruments, providing new concept development methods. This article reviews methods, overviews reported biosensors based on electrochemistry, SPR, microfluidics, nanomaterials CRISPR, discusses their challenges future research prospects detection.

Language: Английский

Citations

4
Advanced protein nanobiosensors to in-situ detect hazardous material in the environment DOI

Nguyễn Hoàng Ly,

Tejraj M. Aminabhavi, Yasser Vasseghian

et al.

Journal of Environmental Management, Journal Year: 2024, Volume and Issue: 366, P. 121727 - 121727

Published: July 14, 2024

Language: Английский

Citations

4
RNA-based diagnostic innovations: A new frontier in diabetes diagnosis and management DOI Creative Commons
Esther Ugo Alum,

Ernest Nnamdi Ikpozu,

Christian Emeka Offor

et al.

Diabetes and Vascular Disease Research, Journal Year: 2025, Volume and Issue: 22(2)

Published: March 1, 2025

Background/Objective: Diabetes mellitus (DM) remains a major global health challenge due to its chronic nature and associated complications. Traditional diagnostic approaches, though effective, often lack the sensitivity required for early-stage detection. Recent advancements in molecular biology have identified RNA molecules, particularly non-coding RNAs such as microRNAs (miRNAs), long (lncRNAs), circular (circRNAs), promising biomarkers diabetes. This review aims explore role of RNA-based diagnosis, prognosis, management diabetes, highlighting their potential revolutionize diabetes care. Method: A comprehensive literature was conducted using electronic databases including PubMed, Scopus, Web Science. Articles published up 2024 were screened analyzed extract relevant findings related diagnostics Emphasis placed on studies demonstrating clinical utility, mechanistic insights, translational molecules. Results: Numerous species, miRNAs miR-375, miR-29, lncRNAs like H19 MEG3, exhibit altered expression patterns diabetic patients. These molecules are involved key regulatory pathways glucose metabolism, insulin resistance, β-cell function. Circulating detectable various biofluids, enabling non-invasive approaches. Emerging technologies, sequencing liquid biopsy platforms, enhanced specificity detection, fostering development novel tools personalized therapeutic strategies. Conclusion: hold significant promise advancing early risk stratification, monitoring Despite current challenges standardization validation, integration into routine practice could transform management, paving way precision medicine Further research multi-center trials essential validate these facilitate approval implementation.

Language: Английский

Citations

0