Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 158341 - 158341
Published: Dec. 1, 2024
Language: Английский
Microchemical Journal, Journal Year: 2024, Volume and Issue: 201, P. 110729 - 110729
Published: May 10, 2024
Language: Английский
Citations
4
ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(6), P. 4062 - 4079
Published: June 4, 2024
This work aimed to develop an enzyme-free semiconductor-assisted electrochemical technique for the selective detection of neurotransmitter dopamine. In this case, electrochemically grown nickel oxyhydroxide [NiO(OH)] thin films were chosen fabricate sensing platform, i.e., electrodes. Chronoamperometry was used deposit on indium tin oxide (ITO) coated glass substrates. The thoroughly characterized establish their structure, composition, phase purity, and attributes. Electrochemical characteristics investigated by means cyclic differential pulse voltammetry, steady-state amperometry, impedance spectroscopy. effects several interfering agents like glucose, sodium chloride, methanol, hydrogen peroxide, paracetamol also studied attributes Significantly high value sensitivity (11.87 μA μM–1 cm–2) obtained dopamine that associated with a limit (LoD) 0.22 μM However, (2.51 LoD (1.20 μM) serotonin inferior compared those performance electrode toward not compromised either in presence only or series other electroactive agents, which makes very much selective. response time 200 ms, is notably fast. Extensive studies effect temperature, pH scan rate developed material have been carried out. electrodes found be stable decay 6.6% oxidation peak current density after 50th cycle. Real-life application checked urine samples from adult male humans yielded encouraging results.
Language: Английский
Citations
4
Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114449 - 114449
Published: March 1, 2025
Language: Английский
Citations
0
Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: unknown, P. 113575 - 113575
Published: Nov. 1, 2024
Language: Английский
Citations
3
Biosensors, Journal Year: 2025, Volume and Issue: 15(1), P. 60 - 60
Published: Jan. 17, 2025
In the current work, MWCNTs/ZnO nanocomposite was successfully synthesized using simple method. Then, FE-SEM, XRD, and EDX techniques were applied for morphological structural characterization. Afterward, a sensitive voltammetric sensor based on modification of screen-printed carbon electrode (SPCE) developed determination doxorubicin in presence dacarbazine. To evaluate electrochemical response MWCNTs/ZnO/SPCE towards doxorubicin, cyclic voltammetry (CV) applied. The showed significant synergistic effect redox reaction doxorubicin. Also, demonstrated an enhanced sensing platform quantification obtaining detection limit (LOD) 0.002 µM sensitivity 0.0897 µA/µM, as determined by differential pulse (DPV) within linear range from 0.007 to 150.0 µM. nanocomposite-modified SPCE high activities oxidation dacarbazine with peak-potential separation 345 mV, which is sufficient presented reproducible stable responses determine Finally, successful performance real samples, recovery 97.1% 104.0% relative standard deviation (RSD) 1.8% 3.5%.
Language: Английский
Citations
0
ACS Applied Electronic Materials, Journal Year: 2024, Volume and Issue: unknown
Published: July 31, 2024
In order to carry out a comparative study on the effect of conduction type electrode materials enzyme-less electrochemical sensing dopamine and serotonin, three different combinations were prepared fluorine-doped tin oxide (FTO)-coated glass substrates. The electrodes FTO/In2O3 (ITO) (n-type), FTO/Ni2O3 (p-type), FTO/ITO/Ni2O3 (n-p junction), which deposited using direct current (DC) sputtering techniques. developed thoroughly characterized, both structurally electrochemically. An actual test environment was simulated by taking series electroactive interfering agents explore in vitro performance prototypes toward serotonin. results indicated that quite selective dopamine, where ITO/Ni2O3 showed best performance. Ultrafast response (9.0 ms) even very low (100 nM, 18.96 ppb) concentration with notably high value sensitivity (5.03 μA μM–1 cm–2) limit detection nanomolar/ppb exhibited electrode. reliability carried respect performance, phase purity, structural properties after rigorous electrodes, encouraging. Only 1.7% degradation peak density observed for 50th cycle measurements. Real sample analysis healthy adult human male urine also performer electrode, yielded significantly rate recovery. experimental data pave path this prototype real-life applications.
Language: Английский
Citations
2
Biosensors, Journal Year: 2024, Volume and Issue: 14(9), P. 422 - 422
Published: Aug. 30, 2024
Depression is currently a major contributor to unnatural deaths and the healthcare burden globally, patient's battle with depression often long one. Because causes, symptoms, effects of medications are complex highly individualized, early identification personalized treatment key improving outcomes. The development wearable electronics, machine learning, other technologies in recent years has provided more possibilities for realization this goal. Conducting regular monitoring through biosensing technology allows comprehensive objective analysis than previous self-evaluations. This includes identifying depressive episodes, distinguishing somatization analyzing etiology, evaluating effectiveness programs. review summarizes research on depression. Special attention given that can be portable or wearable, potential enable patient use outside hospital, periods.
Language: Английский
Citations
1
ACS Omega, Journal Year: 2024, Volume and Issue: 9(50), P. 49545 - 49556
Published: Dec. 3, 2024
Electrochemical sensing has shown great promise in monitoring neurotransmitter levels, particularly dopamine, essential for diagnosing neurological illnesses like Parkinson's disease. Such techniques are easy, cost-effective, and extremely sensitive. The present investigation discusses the synthesis, characterization, potential use of a cysteine-grafted Cu MOF/ZnO/PANI nanocomposite deposited on modified glassy carbon electrode surface nonenzymatic electrochemical dopamine. synthesized was confirmed through X-ray diffraction, Fourier transform infrared, Raman, scanning electron microscopy characterization techniques. Additionally, analysis conducted using cyclic voltammogram, differential pulse voltammetry, chronoamperometry. process determined to be diffusion-controlled oxidation Dopamine underwent spontaneous adsorption an electrochemically reversible mechanism. Despite various biological interfering factors, sensor demonstrated remarkable level selectivity toward Cysteine-grafted produced lowest dopamine detection limit, at 0.39 μM, sensitivity observed as 122.57 μAmM–1 cm–2. Results have that enhanced catalytic conductive properties MOFs, combined with nanostructured materials, primary factors affecting sensor's performance.
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 158341 - 158341
Published: Dec. 1, 2024
Language: Английский
Citations
0