BMJ Open,
Journal Year:
2024,
Volume and Issue:
14(1), P. e075262 - e075262
Published: Jan. 1, 2024
Objective
COVID-19
has
negatively
impacted
mental
health
of
adults
globally
with
increased
rates
psychiatric
comorbidities.
However,
network
analysis
studies
to
examine
comorbidities
and
correlations
between
symptoms
different
disorders
are
uncommon
in
low-income
countries.
This
study
aimed
investigate
the
structure
depression,
anxiety
perceived
stress
among
Addis
Ababa
identify
most
central
bridge
within
depressive-anxiety-perceived
model.
Design
Community-based
cross-sectional
study.
Setting
was
carried
out
on
a
sample
general
population
during
first
year
pandemic.
A
total
1127
participants
were
included
this
study,
which
747
(66.3%)
females,
mean
age
36
years.
Primary
secondary
outcome
measures
Symptoms
measured
using
Patient
Health
Questionnaire,
Generalized
Anxiety
Disorder
Scale
Perceived
Stress
Scale,
respectively.
Network
conducted
structure.
The
centrality
index
expected
influence
(EI)
EI
(1-step)
applied
determine
symptoms.
Case-dropping
procedure
used
stability.
Result
sad
mood
(EI=1.52)
symptom
Irritability
(bridge
EI=1.12)
nervousness
stressed
EI=1.33)
also
served
as
strongest
edge
uncontrollable
worry
(weight=0.36)
community.
had
good
stability
accuracy.
invariant
by
gender
based
invariance
test.
Conclusions
In
core
symptom.
other
identified
should
be
targeted
prevent
adults.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: Feb. 25, 2025
Background:
Comorbidity
of
depression
and
anxiety
is
common
among
adolescents
can
lead
to
adverse
outcomes.
However,
there
limited
understanding
the
latent
characteristics
mechanisms
governing
these
disorders
their
interactions.
Moreover,
few
studies
have
examined
impacts
relevant
risk
protective
factors.
Methods:
This
cross-sectional
study
involved
1,719
students.
Mplus
8.0
software
was
used
conduct
profile
analysis
explore
potential
categories
comorbidities.
R4.3.2
network
core
symptoms,
bridge
disorders,
evaluate
effects
Results:
Three
were
established:
"healthy"
(57.8%),
"mild
depression-mild
anxiety"
(36.6%),
"moderately
severe
depression-moderate
(5.6%).
"Depressed
mood",
"nervousness",
"difficulty
relaxing"
symptoms
in
both
depression-anxiety
comorbidity
Stress
perception
neuroticism
serve
as
bridging
nodes
connecting
some
are
thus
considered
most
prominent
Conclusions:
According
identified
this
study,
targeted
intervention
treatment
be
provided
groups
with
comorbid
anxiety,
thereby
reducing
comorbidities
adolescents.
BMC Psychiatry,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 4, 2025
Childhood
trauma
is
strongly
linked
to
anxiety
and
depression,
significantly
increasing
the
risk
of
negative
outcomes
in
adulthood.
This
study
employed
network
analysis
investigate
complex
interplay
depression
symptoms
among
Chinese
college
students,
focusing
on
identifying
core
most
directly
affected
by
childhood
those
exerting
greatest
influence
others.
Data
were
collected
from
December
2020
January
2021
2,266
students
at
16
institutions
southwestern
eastern
coastal
China.
Depression,
anxiety,
assessed
using
Patient
Health
Questionnaire-9,
Generalized
Anxiety
Disorder-7,
Trauma
Questionnaire-28,
respectively.
Separate
symptom
networks
constructed
for
participants
with
without
experiences.
Central
indices
identify
central
within
each
network.
The
accuracy
stability
then
evaluated.
Finally,
a
comparison
test
was
used
analyze
differences
properties
between
non-trauma
groups.
Loss
Energy
Worry
too
much
group,
while
anhedonia
nervousness
group.
There
significant
difference
global
strength
group
(pFDR<
0.01),
but
no
distribution
edge
weights
two
(pFDR
=0.14).
Anhedonia,
Suicide
ideation
Feeling
afraid
showed
increased
centrality
compared
demonstrates
profound
impact
students.
Further
research
warranted
specific
pathways
through
which
these
develop,
goal
developing
targeted
interventions
this
vulnerable
population.
BMC Psychology,
Journal Year:
2025,
Volume and Issue:
13(1)
Published: May 10, 2025
The
aim
of
this
study
was
to
utilize
network
analysis
explore
the
interconnections
among
anxiety,
depressive,
and
insomnia
symptoms
in
depressed
patients
China.
included
two
surveys,
baseline
survey
conducted
from
May
18,
2020
June
2020,
follow-up
5
months
later.
A
total
4476
completed
survey,
1877
them
survey.
Depression
were
evaluated
using
9-item
Patient
Health
Questionnaire-9
(PHQ-9),
anxiety
7-item
Generalized
Anxiety
Disorder
(GAD-7),
Insomnia
Severity
Index
(ISI).
centrality
indices
are
utilized
analysis,
Network
Comparison
Test
(NCT)
evaluate
differences
between
structures
at
different
time
points.
revealed
that
central
symptom
value
ISI5
("Interfere
with
your
daily
functioning")
networks
ISI4
("Worried/distressed")
networks,
bridge
both
PHQ9-3
("Sleep").
NCT
results
no
significant
edge
weights
global
strength
participants
who
surveys.
Our
suggest
(e.g.,
"Interfere
functioning","Worried/distressed")
("Sleep")
can
be
prioritized
as
a
target
for
intervention
treatment
depression.
Frontiers in Psychiatry,
Journal Year:
2023,
Volume and Issue:
14
Published: Feb. 22, 2023
The
COVID-19
pandemic
and
its
subsequent
health
restrictions
had
an
unprecedented
impact
on
mental
health,
contributing
to
the
emergence
reinforcement
of
various
psychopathological
symptoms.
This
complex
interaction
needs
be
examined
especially
in
a
vulnerable
population
such
as
older
adults.In
present
study
we
analyzed
network
structures
depressive
symptoms,
anxiety,
loneliness
from
English
Longitudinal
Study
Aging
Substudy
over
two
waves
(Months
June-July
November-December
2020).For
this
purpose,
use
measures
centrality
(expected
bridge-expected
influence)
addition
Clique
Percolation
method
identify
overlapping
symptoms
between
communities.
We
also
directed
networks
direct
effects
variables
at
longitudinal
level.UK
adults
aged
>50
participated,
Wave
1:
5,797
(54%
female)
2:
6,512
(56%
female).
Cross-sectional
findings
indicated
that
difficulty
relaxing,
anxious
mood,
excessive
worry
were
strongest
similar
(Expected
Influence)
both
waves,
while
mood
was
one
allowed
interconnection
all
(bridge
expected
influence).
On
other
hand,
sadness
sleeping
reflected
highest
comorbidity
among
during
first
second
respectively.
Finally,
level,
found
clear
predictive
effect
direction
nervousness
symptom,
which
reinforced
by
(difficulties
enjoying
life)
(feeling
being
excluded
or
cut
off
others).Our
suggest
depressive,
anxious,
dynamically
function
context
UK.
Therapeutic Advances in Psychopharmacology,
Journal Year:
2024,
Volume and Issue:
14
Published: Jan. 1, 2024
Background:
Coronavirus
disease
2019
pandemic
pointed
out
significant
mental
symptoms
of
frontline
healthcare
workers
(HCWs).
Objective:
We
aimed
to
estimate
the
prevalence
and
comorbidity
post-traumatic
stress
(PTSS),
depression
anxiety
in
HCWs
from
Fangcang
shelter
hospitals
during
pandemic.
Design:
Demographic
information,
disorder
checklist
for
DSM-5
(PCL-5),
Patient
Health
Questionnaire
(PHQ-9)
Generalized
Anxiety
Disorder
(GAD-7)
were
obtained
online
based
on
stratified
random
sampling
design
April
2022,
with
284
eligible
responses.
Method:
Hierarchical
regression
analyses
applied
investigate
independent
variables
associated
psychological
status
outcomes
(PHQ-9,
GAD-7
PCL-5),
network
explore
using
all
items
PCL-5,
PHQ-9
GAD-7.
Results:
(1)
10.56%,
13.03%
8.10%
reported
PTSS,
symptoms.
Fifty-three
(18.66%)
experienced
at
least
one
health
disorder,
among
which
26.42–37.74%
had
two
or
three
disorders;
(2)
several
influence
factors
identified,
including
medical
professions,
working
hours,
contacted
patients
(
p
<
0.05);
(3)
prominent
bridge
between
PTSS
sleep
problems,
suicide
ideation,
concentration
difficulties
recklessness.
Comorbidity
was
thought
mainly
stem
negative
affect,
such
as
afraid,
anxious,
annoyed
worrying.
Depressed
mood
worry
might
be
good
targets
treatment
anxiety.
Conclusion:
Our
data
suggest
mild
level
give
novel
insights
into
assessment
intervention
comorbidity.