Evaluation of the probiotic, anti-bacterial, anti-biofilm, and safety properties of Lacticaseibacillus paracasei B31-2
LWT,
Journal Year:
2024,
Volume and Issue:
207, P. 116676 - 116676
Published: Aug. 26, 2024
Language: Английский
Changes in Hormonal Profile and Body Mass Index in Women with Polycystic Ovary Syndrome After Probiotic Intake: A 12-Week Placebo-Controlled and Randomized Clinical Study
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(3), P. 405 - 405
Published: Jan. 23, 2025
Introduction:
The
beneficial
effect
of
probiotics
on
the
improvement
carbohydrate
and
lipid
metabolism,
as
well
body
mass
index
(BMI),
has
been
demonstrated
in
various
patient
groups.
We
aimed
to
investigate
a
multi-strain
probiotic
hormonal
balance
women
with
PCOS.
Ethical
approval
was
obtained
from
Bioethical
Committee.
Methods:
study
designed
12-week,
randomized,
double-blind,
placebo-controlled
clinical
study.
SanProbi®
Barrier
capsules,
which
contain
unique
composition
nine
bacteria
strains
(Lactobacillus
Biffidobacterium),
were
used
mean
age
participants
28.42
±
5.62
years.
A
total
50
PCOS,
diagnosed
based
Rotterdam
ESHRE
criteria,
included
Among
them,
25
randomized
placebo
group,
group.
Results:
comparison
changes
individual
hormone
levels
between
groups
confirmed
statistically
significant
differences
for
TSH,
androstenedione,
SHBG,
BMI.
In
case
LH,
statistical
significance
difference
delta
change
group
use
one-tailed
test.
Conclusions:
Probiotic
supplementation
may
serve
an
alternative
supporting
treatment,
especially
phenotype
high
FAI
index.
therapy
is
also
effective
reducing
BMI
overweight
PCOS
Language: Английский
Antimicrobial activity of Lactobacillus casei on Staphylococcus pseudintermedius isolates
Veterinary Dermatology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 27, 2025
Abstract
Background
Antimicrobial
resistance
is
increasing
each
year.
For
example,
in
2019
it
was
directly
responsible
for
an
estimated
>1
million
deaths.
Additionally,
the
development
of
new
drugs
much
slower,
generating
enormous
concerns
about
responses
to
infection
future
health
scenario.
Therefore,
probiotics
have
emerged
as
alternative
antibiotics.
Objectives
This
study
aimed
isolate
and
identify
a
Lactobacillus
casei
from
healthy
canine
skin
investigate
its
antimicrobial
effect
on
isolates
Staphylococcus
pseudintermedius
originating
dogs
with
pyoderma.
Materials
Methods
L.
isolated
samples
collected
sterile
cotton
swab
inner
pinnae
dogs.
It
then
cultured,
identified
using
matrix‐assisted
laser
desorption
ionisation
time‐of‐flight
mass
spectrometry,
tested
against
30
different
clinical
one
American
Type
Culture
Collection
strain
S.
spot‐on‐the‐lawn
technique.
Its
safety
assessed
through
modified
Kirby–Bauer
disc
diffusion
susceptibility
test.
Results
inhibited
growth
all
.
The
mean
value
inhibition
halo
11.3
mm.
A
significant
positive
correlation
(Pearson's
linear
=
0.444;
p
0.014)
noted
between
inhibitory
halos
formed
by
produced
discs
same
isolates.
demonstrated
sensitivity
antimicrobials.
Conclusions
Clinical
Relevance
indicates
that
commensal
bacteria
skin,
specifically
,
control
bacterial
infections
caused
can
be
promising
complementary
or
therapy
antibiotics
relevant
animal
human
health.
Language: Английский
Bibliometric Mapping on the Probiotic Trends in Managing Aquaculture Pathogens.
Food Bioscience,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106372 - 106372
Published: March 1, 2025
Language: Английский
Effect of Bacillus velezensis MT9 on Nile Tilapia (Oreochromis Niloticus) Intestinal Microbiota
Microbial Ecology,
Journal Year:
2025,
Volume and Issue:
88(1)
Published: May 1, 2025
Language: Английский
Inhibition of Candida albicans virulence factor by cyclic dipeptides derived from Aeromonas veronii V03
Published: Oct. 25, 2024
Abstract
Candida
albicans
is
the
most
common
human
fungal
pathogen
with
high
mortality
rates
and
limited
antifungal
treatments.
Inhibition
of
C.
pathogenesis
by
targeting
virulence
factors
provides
a
promising
strategy
for
development
novel
drugs
overcoming
drug
resistance.
In
this
study,
four
structurally
different
cyclic
dipeptides
(or
diketopiperazine(DKP)
were
isolated
identified
as
cyclo(L-Pro-L-Leu),
cyclo(L-Pro-L-Val),
cyclo(D-Pro-L-Phe),
cyclo(L-Pro-D-Tyr)
from
Aeromonas
veronii
V03
their
antimicrobial
potentials
evaluated.
Results
revealed
that
DKPs
exhibited
antibacterial
activity
against
bacterial
pathogens,
such
Staphylococcus
aureus,
Proteus
mirabilis
,
Pseudomonas
aeruginosa,
hydrophila
.
Importantly,
cyclo(D-Pro-L-Phe)
lacking
hydroxyl
groups
showed
potent
inhibitory
effects
non-albicans
species
low
concentrations.
Moreover,
inhibited
traits
albicans,
including
yeast-to-hyphae
transition,
secreted
hydrolases
(aspartic
proteases
phospholipase)
biofilm
formation
in
dose-dependent
manner.
Collectively,
our
findings
suggest
derived
A.
could
potentially
be
developed
antivirulence
agents
infection.
Language: Английский
Adhesion Properties and Pathogen Inhibition of Vaginal-Derived Lactobacilli
Probiotics and Antimicrobial Proteins,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 20, 2024
Language: Английский
Effect of linex treatment on IFN-γ and IL-4 in mice infected with Trichinella
Shimaa Atta,
No information about this author
Zeinab Fahmy,
No information about this author
Eman A. H. Selim
No information about this author
et al.
BMC Infectious Diseases,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Nov. 28, 2024
Abstract
Trichinellosis
is
a
zoonotic,
foodborne
parasitic
infection
causing
muscle
damage.
This
study
investigated
the
potential
therapeutic
effects
of
commercially
available
probiotic
treatment
Linex,
both
alone
and
in
combination
with
Albendazole
(ALB),
on
intestinal
muscular
stages
Trichinella
spiralis
mice,
assessing
outcomes
through
parasitological,
immunological,
histopathological
measures.
first
to
demonstrate
synergistic
effect
combining
Linex
for
trichinellosis
treatment.
By
enhancing
parasitological
immunological
outcomes,
this
combined
therapy
not
only
significantly
reduces
parasite
burden
but
also
modulates
immune
response,
shifting
it
toward
protective
Th1
profile.
In
terms,
highest
adult
larval
count
reduction
was
observed
(100%,
97.7%)
respectively.
Lesser
percentage
were
recorded
(43.2%,
88.4%)
Histopathologically
there
amelioration
inflammatory
cellular
infiltration
all
treated
groups
best
results
Immunologically,
serum
IFN-γ
levels
increased
treatment,
while
IL-4
IL-13
level
decreased
To
conclude;
mice
infected
T.
spirals
could
ameliorate
improve
response.
Language: Английский