Whither unisensory olfactory cortex: processing of visual and auditory stimuli in olfactory cortex, independently of odor associations DOI Creative Commons
Evelina Thunell, Moa G. Peter, Behzad Iravani

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: April 20, 2023

Abstract Primary sensory cortices have been demonstrated to process input from non-preferred modalities, e.g. primary visual cortex reacting auditory stimulation, bringing their presumed specificity into question. Whether this reflects processing of the stimulus per se or originates cross-modal associations is debated. Visual/auditory objects typically strong reciprocal associations; hence, it difficult address question in these modalities. Here, we attempt dissociate between two competing hypotheses whether form activation caused by unisensory turning olfactory system where are generally weaker. Using and with odor ranging none strong, show that posterior piriform cortex, an area known objects, activated both sounds pictures objects. Critically, independent objects’ associations, thereby demonstrating activity not due associations. a Floyd–Warshall algorithm, further amygdala mediate condition-relevant information object-oriented cortices. Importantly, replicate past findings clear crossmodal systems. Our study demonstrates non-olfactory contributes more nuanced view modality olfactory, auditory,

Language: Английский

The brain-gut microbiota network (BGMN) is correlated with symptom severity and neurocognition in patients with schizophrenia DOI Creative Commons

Runlin Peng,

Wei Wang,

Liqin Liang

et al.

NeuroImage, Journal Year: 2025, Volume and Issue: unknown, P. 121052 - 121052

Published: Jan. 1, 2025

Language: Английский

Citations

2
Multisensory integration in the mammalian brain: diversity and flexibility in health and disease DOI Creative Commons

Ilsong Choi,

Ilayda Demir,

Seungmi Oh

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2023, Volume and Issue: 378(1886)

Published: Aug. 7, 2023

Multisensory integration (MSI) occurs in a variety of brain areas, spanning cortical and subcortical regions. In traditional studies on sensory processing, the cortices have been considered for processing information modality-specific manner. The cortices, however, send to other including higher association where multiple modality inputs converge integrate generate meaningful percept. This process is neither simple nor fixed because these areas interact with each via complicated circuits, which can be modulated by numerous internal external conditions. As result, dynamic MSI makes multisensory decisions flexible adaptive behaving animals. Impairments occur many psychiatric disorders, may result an altered perception stimuli abnormal reaction them. review discusses diversity flexibility mammals, humans, primates rodents, as well involved. It further explains how such influences perceptual experiences animals both health disease. article part theme issue ‘Decision control processes perception’.

Language: Английский

Citations

15
Medium Spiny Neurons Mediate Timing Perception in Coordination with Prefrontal Neurons in Primates DOI Creative Commons
Xinhe Liu, Zhiting Zhang, Lu Gan

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 11, 2025

Abstract Timing perception is a fundamental cognitive function that allows organisms to navigate their environment effectively, encompassing both prospective and retrospective timing. Despite significant advancements in understanding how the brain processes temporal information, neural mechanisms underlying these two forms of timing remain largely unexplored. In this study, it aims bridge knowledge gap by elucidating functional roles various neuronal populations striatum prefrontal cortex (PFC) shaping subjective experiences time. Utilizing large‐scale electrode array, recorded responses from over 3000 neurons PFC macaque monkeys during tasks. The analysis classified into distinct groups revealed timings are governed separate processes. Specifically, study demonstrates medium spiny (MSNs) play crucial role facilitating Through cell‐type‐specific manipulation, identified D2‐MSNs as primary contributors Additionally, findings indicate effective processing requires coordination between striatum. summary, advances foundations highlights its behavioral implications.

Language: Английский

Citations

0
Evaluating Pupillometry as a Tool for Assessing Facial and Emotional Processing in Nonhuman Primates DOI Creative Commons
Xinhe Liu, Zhiting Zhang, Ji Dai

et al.

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(6), P. 3022 - 3022

Published: March 11, 2025

Non-human primates (NHPs) are extensively utilized to investigate the neural mechanisms underlying face processing; however, measuring their brain activity necessitates a diverse array of technologies. Pupillometry emerges as convenient, cost-effective, and non-invasive alternative for indirectly assessing activity. To evaluate efficacy pupillometry in facial emotional processing NHPs, this study designed fixation task experimental monkeys (Rhesus macaque) recorded variations pupil size response images with differing characteristics, such species, expression, viewing angles, orientation (upright vs. inverted). All were balanced luminance spatial frequency. A sophisticated eye-tracking system (Eye-link 1000 plus) was employed observe pupils track trajectories they examined faces. Our findings reveal that exhibited larger sizes carnivore faces (versus human faces, p = 0.035), negative conspecific 0.018), profile angles frontal view 0.010). Notably, during 500–1000 ms post-stimulus interval negatively correlated gaze durations directed at those (r −0.357, 0.016). Overall, demonstrates effectively captures subtle differences processing, underscoring its potential valuable tool future cognitive research diagnosis disorders.

Language: Английский

Citations

0
Unisensory visual and auditory objects are processed in olfactory cortex, independently of odor association DOI Creative Commons
Evelina Thunell, Moa G. Peter, Behzad Iravani

et al.

Cortex, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
A Novel Retrograde AAV Variant for Functional Manipulation of Cortical Projection Neurons in Mice and Monkeys DOI
Yefei Chen, Jingyi Wang, Jing Liu

et al.

Neuroscience Bulletin, Journal Year: 2023, Volume and Issue: 40(1), P. 90 - 102

Published: July 11, 2023

Language: Английский

Citations

5
Genetic and Neuronal Basis for Facial Emotion Perception in Humans and Macaques DOI Creative Commons
Li Wang, Bo Zhang, Xiqian Lu

et al.

National Science Review, Journal Year: 2024, Volume and Issue: 11(11)

Published: Oct. 21, 2024

ABSTRACT The ability to rapidly recognize basic facial emotions (e.g. fear) is crucial for social interactions and adaptive functioning. To date, the origin of facial-emotion-recognition remains equivocal. Using a classical twin design in humans, we found clear dissection low high spatial frequencies (LSF HSF) emotion perception: whereas genetic factors contributed individual variation LSF processing, HSF processing largely shaped by environmental effects. Furthermore, content genetically correlated with function amygdala. Crucially, single-unit recording amygdala macaques further revealed dissociation between perception, indicating existence an evolutionarily conserved mechanism. This cross-species study enhances insights into neurobiological dual-route model (subcortical vs. cortical) perception illuminates functional development emotional brain primates.

Language: Английский

Citations

1
Alterations of Audiovisual Integration in Alzheimer’s Disease DOI
Yufei Liu, Zhibin Wang, Tao Wei

et al.

Neuroscience Bulletin, Journal Year: 2023, Volume and Issue: 39(12), P. 1859 - 1872

Published: Oct. 9, 2023

Language: Английский

Citations

3
Neurotensin Modulates Emotional Valence Assignment in the Basolateral Amygdala Through Neuromodulator Gain DOI

Maimaitishalijiang Abudureheman,

Yu-Hao Xiao,

Li-Zang Zeng

et al.

Neuroscience Bulletin, Journal Year: 2024, Volume and Issue: unknown

Published: July 26, 2024

Language: Английский

Citations

0
Whither unisensory olfactory cortex: processing of visual and auditory stimuli in olfactory cortex, independently of odor associations DOI Creative Commons
Evelina Thunell, Moa G. Peter, Behzad Iravani

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: April 20, 2023

Abstract Primary sensory cortices have been demonstrated to process input from non-preferred modalities, e.g. primary visual cortex reacting auditory stimulation, bringing their presumed specificity into question. Whether this reflects processing of the stimulus per se or originates cross-modal associations is debated. Visual/auditory objects typically strong reciprocal associations; hence, it difficult address question in these modalities. Here, we attempt dissociate between two competing hypotheses whether form activation caused by unisensory turning olfactory system where are generally weaker. Using and with odor ranging none strong, show that posterior piriform cortex, an area known objects, activated both sounds pictures objects. Critically, independent objects’ associations, thereby demonstrating activity not due associations. a Floyd–Warshall algorithm, further amygdala mediate condition-relevant information object-oriented cortices. Importantly, replicate past findings clear crossmodal systems. Our study demonstrates non-olfactory contributes more nuanced view modality olfactory, auditory,

Language: Английский

Citations

1