Chili pepper: A delve into its nutritional values and roles in food-based therapy

Food Chemistry Advances, Journal Year: 2025, Volume and Issue: 6, P. 100928 - 100928

Published: Feb. 16, 2025

Language: Английский

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Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review

Indian Journal of Clinical Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Language: Английский

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Capsicum in Clinical Biochemistry: Insights into its Role in Health and Disease

Indian Journal of Clinical Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Language: Английский

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Anthocyanins: From Natural Colorants to Potent Anticancer Agents

Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(5)

Published: May 1, 2025

ABSTRACT Cancer is a prevalent global disease affecting ~20 million individuals, and this burden causes the death of ~9.7 people in 2024. The prevalence rate continuously increasing due to exposure harmful environmental occupational contaminants (toxins chemicals), compromised immune response, genetic modifications, poor lifestyle dietary practices. management cancer challenging demands cost‐effective safe therapeutic strategies. This review accentuates anticancer potential anthocyanins its associated underlying mechanism. Anthocyanins, active components extracted from grapes, berries, black chokeberries, eggplants, currants, sweet cherries, strawberries, plums, red onions, hold antioxidant anti‐inflammatory potential. bioavailability crucial factor imposing their effect, can be improved by microbial phenolic catabolites, provision α‐casein, nano delivery systems. Anthocyanins hinder cell migration, invasion, proliferation inducing apoptosis, suppressing cycle at G0/G1, S, or G2/M stages, modulating signaling pathways such as apoptotic cascades, PI3K/Akt, MAPK, NF‐κB. Moreover, downregulate oncogenes ( Bcl‐2 , MYC HER2 ) improve activity tumor suppressor genes TP53 BRCA1 RB1 ). particularly cyanidin‐3‐ O ‐glucoside, suppress inflammation production pro‐inflammatory cytokines (COX‐2, TNF‐α, IL‐6) colorectal hepatocellular carcinoma. it inhibition mitochondrial dysfunction ovarian cervical malignancies. Although pre‐clinical studies have proved activities, further clinical trials are required validate impact standard dose regimens.

Language: Английский

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When the Gut Speaks: The Hidden Toll of Irritable Bowel Syndrome on Body and Mind

Gastroenterology & Endoscopy, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

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