Optimizing Rare Disease Gait Classification through Data Balancing and Generative AI: Insights from Hereditary Cerebellar Ataxia
Sensors,
Journal Year:
2024,
Volume and Issue:
24(11), P. 3613 - 3613
Published: June 3, 2024
The
interpretability
of
gait
analysis
studies
in
people
with
rare
diseases,
such
as
those
primary
hereditary
cerebellar
ataxia
(pwCA),
is
frequently
limited
by
the
small
sample
sizes
and
unbalanced
datasets.
purpose
this
study
was
to
assess
effectiveness
data
balancing
generative
artificial
intelligence
(AI)
algorithms
generating
synthetic
reflecting
actual
abnormalities
pwCA.
Gait
30
pwCA
(age:
51.6
±
12.2
years;
13
females,
17
males)
100
healthy
subjects
57.1
10.4;
60
40
were
collected
at
lumbar
level
an
inertial
measurement
unit.
Subsampling,
oversampling,
minority
adversarial
networks,
conditional
tabular
networks
(ctGAN)
applied
generate
datasets
be
input
a
random
forest
classifier.
Consistency
explainability
metrics
also
calculated
coherence
generated
dataset
known
ctGAN
significantly
improved
classification
performance
compared
original
traditional
augmentation
methods.
are
effective
methods
for
from
populations
owing
their
ability
improve
diagnostic
models
consistent
explainability.
Language: Английский
The effect of run duration, gait variable and Lyapunov exponent algorithm on the inter-session reliability of local dynamic stability in healthy young people
Alston Kennerley,
No information about this author
Marcus Dunn,
No information about this author
Kane Middleton
No information about this author
et al.
Human Movement Science,
Journal Year:
2025,
Volume and Issue:
99, P. 103325 - 103325
Published: Jan. 30, 2025
Local
dynamic
stability
(LDS)
of
gait
has
been
used
to
differentiate
between
healthy
and
injured
populations,
establishing
its
potential
as
an
indicator
a
new
objective
measure
assess
function
following
injury.
For
LDS
be
reliable
assessment
tool
progression
during
rehabilitation,
it
must
provide
consistent
sensitive
inter-session
measures.
Methodological
factors
such
trial
duration,
variable,
Lyapunov
Exponent
(LyE)
algorithm
can
influence
estimation
reliability.
Young
people
are
high-risk
population
for
sport-related
injuries,
running
is
key
activity
rehabilitation
regularly
assessed.
Therefore,
the
effects
run
LyE
choice
on
reliability
sensitivity
measures
in
young
were
investigated.
Sixteen
participants
ran
treadmill
two
separate
sessions
(difference
7
±
5
days).
was
calculated
using
both
Rosenstein
Wolf
durations
1-,
2-,
3-,
4-
5-min
knee
flexion
angle
medio-lateral
acceleration
pelvis
thorax
from
each
session.
The
relative
absolute
intraclass
correlation
coefficient
standard
error
measurement.
change
quantified
by
minimal
detectable
change.
Results
showed
that
longer
produced
higher
minimum
duration
4
min
recommended
achieve
moderate-to-good
across
all
variables
algorithms.
However,
shorter
2-3
may
still
sufficient
when
or
angle,
particularly
with
algorithm,
which
also
improves
These
findings
practical
guidance
methodological
choices
calculating
support
their
use
tools
monitoring
tracking
progress
Language: Английский
Might patients with cerebellar ataxia benefit from the computer assisted rehabilitation ENvironment (CAREN)? A pilot study focusing on gait and balance
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: June 24, 2024
Ataxia
is
a
neurological
symptom
that
causes
decreased
balance,
loss
of
coordination,
and
gait
alterations.
Innovative
rehabilitation
devices
like
virtual
reality
(VR)
systems
can
provide
task-oriented,
repetitive
intensive
training
with
multisensorial
feedback,
thus
promoting
neuroplastic
processes.
Among
these
VR
technologies,
the
Computer
Assisted
Rehabilitation
ENvironment
(CAREN)
associates
split
belt
treadmill
on
6-degrees
freedom
platform
180°
screen
Vicon
motion
capture
system
to
monitor
patients'
movements
during
sessions.
Language: Английский
Differences in Trunk Acceleration-Derived Gait Indexes in Stroke Subjects with and without Stroke-Induced Immunosuppression
Sensors,
Journal Year:
2024,
Volume and Issue:
24(18), P. 6012 - 6012
Published: Sept. 17, 2024
:
Stroke-induced
immunosuppression
(SII)
represents
a
negative
rehabilitative
prognostic
factor
associated
with
poor
motor
performance
at
discharge
from
neurorehabilitation
unit
(NRB).
This
study
aims
to
evaluate
the
association
between
SII
and
gait
impairment
NRB
admission.
Language: Английский
Local Dynamic Stability of Trunk During Gait Can Detect Dynamic Imbalance in Subjects with Episodic Migraine
Sensors,
Journal Year:
2024,
Volume and Issue:
24(23), P. 7627 - 7627
Published: Nov. 28, 2024
Motion
sensitivity
symptoms,
such
as
dizziness
or
unsteadiness,
are
frequently
reported
non-headache
symptoms
of
migraine.
Postural
imbalance
has
been
observed
in
subjects
with
vestibular
migraine,
chronic
and
aura.
We
aimed
to
assess
the
ability
largest
Lyapunov's
exponent
for
a
short
time
series
(sLLE),
which
reflects
cope
internal
perturbations
during
gait,
detect
differences
local
dynamic
stability
between
individuals
migraine
without
aura
(MO)
an
episodic
pattern
attacks
healthy
(HS).
Language: Английский