Gut-brain axis as a bridge in obesity and depression: Mechanistic exploration and therapeutic prospects DOI

Ruiying Fang,

Xiaoxia Pan, Xuejun Zeng

et al.

World Journal of Psychiatry, Journal Year: 2024, Volume and Issue: 15(1)

Published: Dec. 18, 2024

A recent study by Wang et al, published in the World Journal of Psychiatry, provided preventative and therapeutic strategies for comorbidity obesity depression. The gut-brain axis, which acts as a two-way communication system between gastrointestinal tract central nervous system, plays pivotal role pathogenesis these conditions. Evidence suggests that metabolic byproducts, such short-chain fatty acids, lipopolysaccharide bile are generated gut microbiota, along with neurotransmitters inflammatory mediators within modulate host's processes, neuronal regulation, immune responses through diverse mechanisms. interaction depression via axis involves disruptions microbiota balance, responses, alterations neuroendocrine system. Modulating example, ketogenic diet, use probiotics, supplementation antioxidants, offers new remedial approaches Future research explores mechanisms is needed to provide more evidence clinical treatment.

Language: Английский

The Burden of adolescent depression and the impact of COVID-19 across 204 countries and regions from 1990 to 2021: results from the 2021 global burden of disease study DOI Creative Commons

Feiyun Zhu,

Ying Yang,

Tongle Yin

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 15, 2025

Language: Английский

Citations

2

Analysis of Student Interaction and Social Skills in Game Activities in Elementary School in Indonesian Context DOI Open Access

Zuni Eka Tiyas Rifayanti,

Evi Rizqi Salamah,

Poonkeat Monkonsawasd

et al.

IJORER International Journal of Recent Educational Research, Journal Year: 2025, Volume and Issue: 6(1), P. 43 - 55

Published: Jan. 30, 2025

Objective: Social skills are one of the basic that students must have. How important social Elementary school expected to be able recognize and implement in their future lives. However, practice at school, have fewer skills. Due lack interaction joint learning activities between elementary schools. Through communicating, even playing. This research aims analyze types games can foster students. Method: uses a qualitative method with descriptive approach. The subjects were 15 Wringinrejo, Mojokerto. Research stages (1) preparation stage, researcher pr, prepares plan creates interviews, observations, documentation, guidelines. (2) Implementation Stage, conducted field study by carrying out observation as well taking documentation; 3) Findings Results: analyzed findings made conclusions from results continued final namely (4) Reporting Stage using data, documented. Result: this show excellent through group play such mazes marbles suitable for solitary because they proven stimulate children interact socially physical process improve skills.Novelty: researcher's hope researchers is look more deeply students' level innovative strategies, media, or other methods instilling

Language: Английский

Citations

0

Global prevalence of cannabis and amphetamine/methamphetamine use among adolescents in 47 countries: a population-based study from WHO database DOI

Yejun Son,

Seohyun Hong,

Yesol Yim

et al.

World Journal of Pediatrics, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

Language: Английский

Citations

0

Decrease in Pediatric Farm-Related Injuries Presenting to United States Emergency Departments: A National Study from 2014-2023 DOI

Charu Jain,

Uma Balachandran,

Luca M. Valdivia

et al.

Injury, Journal Year: 2025, Volume and Issue: unknown, P. 112299 - 112299

Published: March 1, 2025

Language: Английский

Citations

0

Global burden of antidepressant-associated seizures from 1967 to 2023: A comparative analysis of the international pharmacovigilance database DOI
Hanseul Cho, Kyeongmin Lee, Sheng‐Min Wang

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0

Machine learning-driven risk prediction and feature identification for major depressive disorder and its progression: an exploratory study based on five years of longitudinal data from the US national health survey DOI

Youbei Lin,

Chuang Li,

Hongyu Li

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0

Anxiety and Depression in Healthcare Workers Two Years After COVID-19 Infection and Scale Validation DOI
Lin Zhang,

Jingli Wen,

Ling Yuan

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 14, 2025

Abstract Objective: This study aims to assess the levels of anxiety and depression among healthcare workers two years post COVID-19 infection validate reliability validity PHQ-9 GAD-7 scales in this population. Methods: cross-sectional was conducted June 2024 using a simple random sampling approach survey institution workers. A total 1,038 valid samples were collected, assessed scales. Participants included such as doctors, nurses, administrative staff, students. Data analysis descriptive statistics, correlation analysis, univariate, multivariate analyses explore effects variables occupation gender on depression. Results: Long COVID reported 50.8% participants. Occupational categories significantly influenced levels: compared students (reference group), staff exhibited lower scores. Non-long participants showed scores than those with long COVID. Additionally, demonstrated high Conclusion: Two after infection, remain by occupational category status. For workers, particularly student groups, policymakers administrators should consider optimizing mental health support systems. includes implementing regular screenings, providing personalized psychological interventions, offering counseling services, reducing work-related stress, promoting use assessment tools improve well-being

Language: Английский

Citations

0

Anxiety and depression in healthcare workers 2 years after COVID-19 infection and scale validation DOI Creative Commons
Lin Zhang,

Jingli Wen,

Ling Yuan

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 22, 2025

Language: Английский

Citations

0

The global, regional, and national burden and trends of anxiety disorders among women of childbearing age from 1990 to 2021: Estimates from the global burden of disease study 2021 DOI
Yuchang Fei,

Jiewen Liu,

Shanshan Gong

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0

Advances in the prevalence and treatment of depression for adolescents: a review DOI Creative Commons

Chunyu Yin,

Mengting Xu,

Zhiyuan Zong

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: May 6, 2025

Depression is a psychological condition in adolescents caused by various factors. Many serious consequences can be associated with depression, such as irritability, emotional instability, and suicide. Meanwhile, the incidence of depression suicide among was also affected during pandemic COVID-19 2019. This phenomenon adolescent should drawn extensive concern community, which affects their physical mental health. review describes epidemiology, high-risk factors, treatment depression. The onset probably attributable to preterm birth, growth environment, genetic. We identify that pandemic, initiated late 2019,affects Antidepressants psychotherapy are conventional treatments for depressive disorders. However, it controversial whether antidepressants effective safer psychotherapy, combination two could provide more benefit this population than alone. summarize some developed novel targets. Improving efficacy safety reduce rate primary goal clinical research. Existing modalities drugs not sufficient achieve demands, so new therapeutic targets will promising patients. A variety factors contribute adolescents. Adolescent mainly treated non-pharmacological. guideline-recommended used if uncontrolled non-pharmacological, but adverse drug reactions suicidal ideation closely monitored.

Language: Английский

Citations

0