Piezoelectricity and flexoelectricity in biological cells: the role of cell structure and organelles
Biomechanics and Modeling in Mechanobiology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 26, 2024
Language: Английский
Flexoelectricity in Biological Materials and Its Potential Applications in Biomedical Research
Bioengineering,
Journal Year:
2025,
Volume and Issue:
12(6), P. 579 - 579
Published: May 28, 2025
Flexoelectricity
arises
in
materials
under
strain
gradients,
which
can
be
particularly
significant
for
situations
the
existence
of
other
electromechanical
properties
is
absent
or
generating
large
flexoelectric
achievable.
This
effect
has
also
been
observed
some
biological
materials,
whose
understanding
hugely
help
to
further
enhance
our
vital
processes
like
mechanotransduction,
as
well
development
applications
regenerative
medicine
and
drug
delivery.
While
field
flexoelectricity
a
relevant
topic
relatively
new
still
developing,
current
study
aims
review
available
results
on
effects
such
cells
cell
membranes,
hearing
mechanisms,
bone,
their
potential
biomedical
research.
Therefore,
we
first
provide
brief
background
two
main
couplings
(piezoelectricity
flexoelectricity)
further,
how
experimentally
theoretically
identified.
We
then
different
aim
study.
Within
that,
additional
emphasis
influence
this
bone
remodeling.
In
particular,
outlines
limitations
provides
directions
future
work,
emphasizing
crucial
role
next-generation
devices
optimizing
function
area
Language: Английский
VII Congress of Russian Biophysicists—2023, Krasnodar, Russia
Biophysical Reviews,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 13, 2023
Language: Английский
Tubulin Homologs in Bacteria and Archaea
N. A. Rumyantseva,
No information about this author
D. M. Golofeeva,
No information about this author
A. A. Khasanova
No information about this author
et al.
Microbiology,
Journal Year:
2024,
Volume and Issue:
93(3), P. 243 - 258
Published: May 14, 2024
Language: Английский
Tubulin Homologs in Bacteria and Archaea
N. A. Rumyantseva,
No information about this author
D. M. Golofeeva,
No information about this author
A. A. Khasanova
No information about this author
et al.
Микробиология,
Journal Year:
2024,
Volume and Issue:
93(3), P. 249 - 266
Published: Sept. 30, 2024
Language: Английский
Exploring the Effects of Polyglutamylation of α-Tubulin C-terminal Regions Through All-Atom Molecular Dynamics
Mathematical Biology and Bioinformatics,
Journal Year:
2024,
Volume and Issue:
19(2), P. 418 - 426
Published: Dec. 4, 2024
The
tubulin
cytoskeleton,
consisting
of
a
network
microtubules,
is
key
intracellular
system
that
supports
the
execution
numerous
vital
cellular
functions.
Its
operation
regulated
by
post-translational
modifications,
which
are
introduced
and
edited
enzymes,
recognized
regulatory
proteins,
or
directly
influence
properties
tubulins.
One
such
modification
polyglutamylation
C-terminal
regions
tubulin.
In
this
study,
we
investigated
effect
adding
additional
glutamate
residues
on
dynamics
α-tubulin
their
interactions
with
globular
domains
using
all-atom
molecular
simulations.
analysis
simulation
data
totaling
over
three
microseconds
for
both
modified
unmodified
revealed
decreases
average
distance
between
base
tip
unstructured
region,
increasing
likelihood
its
contact
domain
protein,
including
polymerization
interface.
These
findings
suggest
may
act
as
factor
influencing
kinetics
microtubule
assembly.
Language: Английский