JAMA,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 19, 2024
This
Viewpoint
summarizes
recent
updates
to
the
Declaration
of
Helsinki,
discusses
its
relevance
in
context
artificial
intelligence
(AI)
health
research,
and
highlights
issues
that
could
affect
future
implementation
as
use
AI
research
increases.
International Journal of Surgery,
Journal Year:
2023,
Volume and Issue:
109(12), P. 4211 - 4220
Published: Oct. 6, 2023
Clinical
trials
are
the
essential
assessment
for
safe,
reliable,
and
effective
drug
development.
Data-related
limitations,
extensive
manual
efforts,
remote
patient
monitoring,
complexity
of
traditional
clinical
on
patients
drive
application
Artificial
Intelligence
(AI)
in
medical
healthcare
organisations.
For
expeditious
streamlined
trials,
a
personalised
AI
solution
is
best
utilisation.
provides
broad
utility
options
through
structured,
standardised,
digitally
driven
elements
research.
The
time-consuming
process
with
recruitment,
enrolment,
frequent
adherence
retention.
With
an
AI-powered
tool,
automated
data
can
be
generated
managed
trial
lifecycle
all
records
history
as
patient-centric
AI.
intelligently
interpret
data,
feed
downstream
systems,
automatically
fill
out
required
analysis
report.
This
article
explains
how
has
revolutionised
innovative
ways
collecting
biosimulation,
early
disease
diagnosis
overcomes
challenges
more
precisely
cost
time
reduction,
improved
efficiency,
development
research
less
need
rework.
future
implications
to
accelerate
important
because
its
fast
output
overall
utility.
npj Vaccines,
Journal Year:
2024,
Volume and Issue:
9(1)
Published: Jan. 20, 2024
Computer-aided
discovery
of
vaccine
targets
has
become
a
cornerstone
rational
design.
In
this
article,
I
discuss
how
Machine
Learning
(ML)
can
inform
and
guide
key
computational
steps
in
design
concerned
with
the
identification
B
T
cell
epitopes
correlates
protection.
provide
examples
ML
models,
as
well
types
data
predictions
for
which
they
are
built.
argue
that
interpretable
potential
to
improve
immunogens
also
tool
scientific
discovery,
by
helping
elucidate
molecular
processes
underlying
vaccine-induced
immune
responses.
outline
limitations
challenges
terms
availability
method
development
need
be
addressed
bridge
gap
between
advances
their
translational
application
Journal of Translational Medicine,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: April 30, 2024
Abstract
Upon
a
diagnosis,
the
clinical
team
faces
two
main
questions:
what
treatment,
and
at
dose?
Clinical
trials'
results
provide
basis
for
guidance
support
official
protocols
that
clinicians
use
to
base
their
decisions.
However,
individuals
do
not
consistently
demonstrate
reported
response
from
relevant
trials.
The
decision
complexity
increases
with
combination
treatments
where
drugs
administered
together
can
interact
each
other,
which
is
often
case.
Additionally,
individual's
treatment
varies
changes
in
condition.
In
practice,
drug
dose
selection
depend
significantly
on
medical
protocol
team's
experience.
As
such,
are
inherently
varied
suboptimal.
Big
data
Artificial
Intelligence
(AI)
approaches
have
emerged
as
excellent
decision-making
tools,
but
multiple
challenges
limit
application.
AI
rapidly
evolving
dynamic
field
potential
revolutionize
various
aspects
of
human
life.
has
become
increasingly
crucial
discovery
development.
enhances
across
different
disciplines,
such
medicinal
chemistry,
molecular
cell
biology,
pharmacology,
pathology,
practice.
addition
these,
contributes
patient
population
stratification.
need
healthcare
evident
it
aids
enhancing
accuracy
ensuring
quality
care
necessary
effective
treatment.
pivotal
improving
success
rates
increasing
significance
discovery,
development,
trials
underscored
by
many
scientific
publications.
Despite
numerous
advantages
AI,
advancing
Precision
Medicine
(PM)
remote
monitoring,
unlocking
its
full
requires
addressing
fundamental
concerns.
These
concerns
include
quality,
lack
well-annotated
large
datasets,
privacy
safety
issues,
biases
algorithms,
legal
ethical
challenges,
obstacles
related
cost
implementation.
Nevertheless,
integrating
medicine
will
improve
diagnostic
outcomes,
contribute
more
efficient
delivery,
reduce
costs,
facilitate
better
experiences,
making
sustainable.
This
article
reviews
applications
development
sustainable,
highlights
limitations
applying
AI.
Fraud
detection,
risk
management,
and
algorithmic
trading
optimization
are
being
revolutionized
by
AI
in
financial
services.
reduces
false
positives
speeds
up
fraud
detection
spotting
trends
anomalies
real
time
using
advanced
machine
learning
techniques.
Financial
institutions
can
now
fight
sophisticated
cyber
attacks
with
AI-powered
systems
that
analyze
massive
databases
detect
illicit
conduct
unparalleled
accuracy.
predictive
analytics
changing
how
organizations
identify
mitigate
risks.
Institutions
predict
credit
defaults,
market
swings,
operational
weaknesses
big
data
AI.
Natural
language
processing
(NLP)
techniques
extracting
insights
from
unstructured
sources
including
regulatory
filings
news
to
improve
decision-making.
Real-time
monitoring
enable
proactive
interventions
reduce
losses
assure
compliance.
is
transforming
trading,
another
breakthrough.
Advanced
models
historical
live
price
movements,
find
arbitrage
opportunities,
execute
trades
milliseconds.
Reinforcement
helping
design
adaptable
algorithms
respond
changes,
increasing
profitability
reducing
risk.
also
promotes
ethical
transparent
tactics,
solving
manipulation
problems.
This
study
analyses
the
newest
applications
services
their
disruptive
influence.
Generative
AI,
federated
learning,
quantum
computing
will
further
transform
sector.
adoption
has
many
benefits,
but
privacy,
bias,
legal
complexity
must
be
addressed
sustain
progress.
efficiency,
resilience,
creativity,
creating
a
future
where
technology
drives
trust
strategic
advantage.
Diagnostics,
Journal Year:
2025,
Volume and Issue:
15(3), P. 397 - 397
Published: Feb. 6, 2025
Radioimmunotherapy
(RIT)
is
a
novel
cancer
treatment
that
combines
radiotherapy
and
immunotherapy
to
precisely
target
tumor
antigens
using
monoclonal
antibodies
conjugated
with
radioactive
isotopes.
This
approach
offers
personalized,
systemic,
durable
treatment,
making
it
effective
in
cancers
resistant
conventional
therapies.
Advances
artificial
intelligence
(AI)
present
opportunities
enhance
RIT
by
improving
precision,
efficiency,
personalization.
AI
plays
critical
role
patient
selection,
planning,
dosimetry,
response
assessment,
while
also
contributing
drug
design
classification.
review
explores
the
integration
of
into
RIT,
emphasizing
its
potential
optimize
entire
process
advance
personalized
care.
AI-driven
customer
service
is
revolutionizing
how
businesses
interact
with
customers
by
improving
personalization,
loyalty,
and
satisfaction
through
data-driven
insights
responsive
interactions.
AI
technologies
like
machine
learning
(ML),
natural
language
processing
(NLP),
generative
models
allow
companies
to
scale
experiences
that
match
individual
preferences,
behaviors,
needs.
tools
in
service,
such
as
chatbots
virtual
assistants,
are
response
times
issue
resolution,
increasing
loyalty.
Companies
can
analyze
massive
datasets
real
time
using
improve
profiles
predict
future
systems
boost
brand
loyalty
personalizing
interactions
making
feel
valued.
Additionally,
ChatGPT
engagement
reducing
friction
providing
human-like
responses
conversational
experiences.
sentiment
analysis
help
anticipate
dissatisfaction
assessing
emotions
feedback.
Along
AI-based
solutions
programs
them
more
dynamic
engaging.
Businesses
identify
high-value
customers,
personalize
offers,
encourage
repeat
business
predictive
analytics.
Despite
these
advances,
ethical
issues
data
privacy
interaction
must
be
addressed.
As
evolves,
balancing
automation
personalized
human
crucial.
This
paper
examines
current
trends,
case
studies,
developments
demonstrate
transform
environments
into
customer-centric,
responsive,
adaptable
ones
foster
long-term
satisfaction.
Diseases,
Journal Year:
2025,
Volume and Issue:
13(1), P. 24 - 24
Published: Jan. 20, 2025
Background:
Cancer
remains
a
leading
cause
of
morbidity
and
mortality
worldwide.
Traditional
treatments
like
chemotherapy
radiation
often
result
in
significant
side
effects
varied
patient
outcomes.
Immunotherapy
has
emerged
as
promising
alternative,
harnessing
the
immune
system
to
target
cancer
cells.
However,
complexity
responses
tumor
heterogeneity
challenges
its
effectiveness.
Objective:
This
mini-narrative
review
explores
role
artificial
intelligence
[AI]
enhancing
efficacy
immunotherapy,
predicting
responses,
discovering
novel
therapeutic
targets.
Methods:
A
comprehensive
literature
was
conducted,
focusing
on
studies
published
between
2010
2024
that
examined
application
AI
immunotherapy.
Databases
such
PubMed,
Google
Scholar,
Web
Science
were
utilized,
articles
selected
based
relevance
topic.
Results:
significantly
contributed
identifying
biomarkers
predict
immunotherapy
by
analyzing
genomic,
transcriptomic,
proteomic
data.
It
also
optimizes
combination
therapies
most
effective
treatment
protocols.
AI-driven
predictive
models
help
assess
response
guiding
clinical
decision-making
minimizing
effects.
Additionally,
facilitates
discovery
targets,
neoantigens,
enabling
development
personalized
immunotherapies.
Conclusions:
holds
immense
potential
transforming
related
data
privacy,
algorithm
transparency,
integration
must
be
addressed.
Overcoming
these
hurdles
will
likely
make
central
component
future
offering
more
treatments.