Integrated environmental surveillance: the role of wastewater, air, and surface microbiomes in global health security DOI Open Access
Manuela Oliveira, Bharath Prithiviraj, Olayinka Osuolale

et al.

Water Emerging Contaminants & Nanoplastics, Journal Year: 2025, Volume and Issue: 4(2)

Published: May 26, 2025

In recent years, particularly following the COVID-19 pandemic, wastewater-based epidemiology (WBE) has emerged as an effective tool for early detection of disease outbreaks. This manuscript presents a novel perspective on WBE by highlighting sewage predictive instrument, capable providing near-real-time, community-level pathogen surveillance and anticipating mitigating future pandemics even before first clinical symptoms are detected. approach enables cost-effective, non-invasive, population-wide monitoring infectious diseases’ emergence, evolution, decline. By identifying pathogens in human waste (e.g., viruses bacteria), delivers real-time insights into infection trends, encompassing data from asymptomatic pre-symptomatic populations, enabling timely interventions public health authorities. Among key advantages its capacity to encompass large pinpoint transmission hotspots, facilitate resource allocation containment efforts. The efficacy predicting already been validated during potential critical component pandemic response preparedness. However, this also challenges such sample variability, environmental factors, infrastructure limitations. Through comprehensive review state-of-art available topic, including almost 300 published papers, present emphasizes expected impact integrating global frameworks discusses applications emerging diseases, aiming provide multidimensional overview integration with other tools.

Language: Английский

Detection of parasites in food and water matrices by shotgun metagenomics: A narrative review DOI Creative Commons
Paolo Vatta, Simone M. Cacciò

Food and Waterborne Parasitology, Journal Year: 2025, Volume and Issue: 39, P. e00265 - e00265

Published: April 21, 2025

Language: Английский

Citations

0
One-Year Monitoring of the Evolution of SARS-CoV-2 Omicron Subvariants Through Wastewater Analysis (Central Italy, August 2023–July 2024) DOI Creative Commons
A. G. Nappo, Maya Petricciuolo, Giulia Berno

et al.

Life, Journal Year: 2025, Volume and Issue: 15(6), P. 850 - 850

Published: May 24, 2025

Wastewater surveillance has proven to be a cost-effective, non-invasive method for monitoring the spread and evolution of SARS-CoV-2, yet its value during today’s low-incidence phase is still being defined. Between August 2023 July 2024, 42 composite wastewater samples were collected in Perugia, Italy analyzed using RT-qPCR whole-genome sequencing identify circulating SARS-CoV-2 lineages. In parallel, clinical (respiratory tract samples) analyzed, allowing direct comparisons confirm robustness findings. The sewage viral loads ranged from 8.9 × 105 4.9 107 genome copies inhabitant−1 day−1, outlining two modest community waves (September–December May–July 2024). Sequencing resolved 403 Omicron lineages revealed three successive subvariant phases: (i) XBB.* dominance (August–October 2023), when late-Omicron XBB subvariants (mainly EG.5.* XBB.1.5) accounted almost all genomes; (ii) BA.2.86/JN surge (November 2023–March 2024), which BA.2.86 subvariant, driven mainly by JN descendants (especially JN.1), rapidly displaced peaked at 89% February 2024; (iii) KP.* takeover (April–July with JN.1-derived KP rising steadily KP.3 reaching 81% thereby becoming dominant lineage. Comparisons data demonstrated how former presented much higher diversity Importantly, some (including BA.2.86*) detected weeks months prior identification, longer periods. Taken together, obtained validated as an effective early warning system, especially periods low infection prevalence and/or limited molecular testing efforts. This methodology can thus complement offering valuable insights into dynamics level enhancing pandemic preparedness.

Language: Английский

Citations

0
Integrated environmental surveillance: the role of wastewater, air, and surface microbiomes in global health security DOI Open Access
Manuela Oliveira, Bharath Prithiviraj, Olayinka Osuolale

et al.

Water Emerging Contaminants & Nanoplastics, Journal Year: 2025, Volume and Issue: 4(2)

Published: May 26, 2025

In recent years, particularly following the COVID-19 pandemic, wastewater-based epidemiology (WBE) has emerged as an effective tool for early detection of disease outbreaks. This manuscript presents a novel perspective on WBE by highlighting sewage predictive instrument, capable providing near-real-time, community-level pathogen surveillance and anticipating mitigating future pandemics even before first clinical symptoms are detected. approach enables cost-effective, non-invasive, population-wide monitoring infectious diseases’ emergence, evolution, decline. By identifying pathogens in human waste (e.g., viruses bacteria), delivers real-time insights into infection trends, encompassing data from asymptomatic pre-symptomatic populations, enabling timely interventions public health authorities. Among key advantages its capacity to encompass large pinpoint transmission hotspots, facilitate resource allocation containment efforts. The efficacy predicting already been validated during potential critical component pandemic response preparedness. However, this also challenges such sample variability, environmental factors, infrastructure limitations. Through comprehensive review state-of-art available topic, including almost 300 published papers, present emphasizes expected impact integrating global frameworks discusses applications emerging diseases, aiming provide multidimensional overview integration with other tools.

Language: Английский

Citations

0