Dietary Polysaccharides Exert Anti-Fatigue Functions via the Gut-Muscle Axis: Advances and Prospectives

Foods, Journal Year: 2023, Volume and Issue: 12(16), P. 3083 - 3083

Published: Aug. 17, 2023

Due to today’s fast-paced lifestyle, most people are in a state of sub-health and face “unexplained fatigue”, which can seriously affect their health, work efficiency, quality life. Fatigue is also common symptom several serious diseases such as Parkinson’s, Alzheimer’s, cancer, etc. However, the contributing mechanisms not clear, there currently no official recommendations for treatment fatigue. Some dietary polysaccharides often used health care supplements; these have been reported specific anti-fatigue effects, with minor side effects rich pharmacological activities. Dietary be activated during food processing or gastrointestinal transit, exerting unique effects. This review aims comprehensively summarize evaluate latest advances biological processes exercise-induced fatigue, understand possible molecular alleviating systematically elaborate roles gut microbiota gut-muscle axis this process. From perspective axis, investigating relationship between fatigue will enhance our understanding may lead significant breakthrough regarding mechanism paper provide new perspectives further research into use science nutrition, could help develop potential agents open up novel therapies conditions.

Language: Английский

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Live and Heat-Killed Probiotic Lactobacillus paracasei PS23 Accelerated the Improvement and Recovery of Strength and Damage Biomarkers after Exercise-Induced Muscle Damage

Nutrients, Journal Year: 2022, Volume and Issue: 14(21), P. 4563 - 4563

Published: Oct. 30, 2022

Excessive, high-intensity or inappropriate exercise may cause muscle damage. How to speed up recovery and reduce discomfort are currently very important issues for athletes sports people. Past research has shown that probiotics can improve inflammation oxidative stress, as well performance antifatigue. However, further is needed confirm the benefits In this double-blind design study, all subjects were randomly assigned placebo, a live Lactobacillus paracasei group (L-PS23, 2 × 1010 colony forming unit (CFU)/day), heat-killed L. (HK-PS23, cells/day), supplemented six consecutive weeks. Afterwards, completed 100 maximal vertical jumps bring about exercise-induced damage (EIMD). Countermovement jump (CMJ), isometric mid-thigh pull (IMTP), Wingate anaerobic test (WAnT), blood tests markers of made pre-exercise 3, 24, 48 h post exercise. The results show both L-PS23 HK-PS23 supplementation significantly slowed loss strength after injury, they reduced production (p < 0.05). addition, had accelerating improvement strength, injury inflammation, slowing decline in testosterone concentrations Especially group, there was better trend. conclusion, we found weeks prevented improved inflammatory markers, with protective, accelerated anti-fatigue benefits.

Language: Английский

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Effects of Multispecies Probiotics on Growth, Hematology, and Gut Health of Stinging Catfish (Heteropneustes fossilis) in Biofloc System

Water, Journal Year: 2023, Volume and Issue: 15(14), P. 2519 - 2519

Published: July 9, 2023

Probiotics are gaining popularity both empirically and scientifically as eco-friendly alternatives in aquaculture. The present research proposed to examine the influences of selective probiotics on growth, hematology, microbes, morphology intestine stinging catfish (Heteropneustes fossilis) a biofloc system. Additionally, this study evaluated benefit–cost ratio (BCR) specific used Stinging fingerlings (average weight 0.86 ± 0.26 g) were equally distributed (250 fingerlings/400 L water-filled PVC tank) into three treatment groups reared for 16 weeks. Two commercial (CP-1 CP-2) one laboratory-developed probiotic study. results showed significantly higher growth (weight gain rate), feed efficiency, improved intestinal microbiota, enhanced fish with Moreover, indicators increased immune responses, such enhancements mucosal fold, width enterocytes lamina propria, abundance goblet cells, also observed probiotics. BCR, which determined business profitability, was highest Therefore, suggest that economically viable environmentally friendly stimulators culture

Language: Английский

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Physical Exercise and the Gut Microbiome: A Bidirectional Relationship Influencing Health and Performance

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3663 - 3663

Published: Oct. 28, 2024

Background/Objectives: The human gut microbiome is a complex ecosystem of microorganisms that can influence our health and exercise habits. On the other hand, physical also impact microbiome, affecting health. Our narrative review examines bidirectional relationship between activity as well potential for targeted probiotic regimens to enhance sports performance. Methods: We conducted comprehensive literature select articles published up till January 2024 on topics exercise, sports, probiotics, microbiota from major scientific databases, incorporating over 100 studies. Results: found varies with type intensity exercise. Moderate promotes healthy immune system, while high-intensity long duration cause leaky consequent systemic inflammation, which may disrupt microbial balance. Combining aerobic resistance training significantly affects bacterial diversity, linked lower prevalence chronic metabolic disorders. Furthermore, enhances increases SCFA production, improves nutrient utilization, modulates neural hormonal pathways, improving barrier integrity. findings showed supplementation associated decreased enhanced performance, fewer gastrointestinal disturbances, suggesting mutually influential. Conclusions: exemplified by how promote beneficial bacteria potentially ability through various mechanisms. These underscore importance adding tailored consider individual profiles into programs.

Language: Английский

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Bacillus coagulans GBI-30, 6086 improves amino acid absorption from milk protein

Nutrition & Metabolism, Journal Year: 2020, Volume and Issue: 17(1)

Published: Oct. 23, 2020

Abstract Background Probiotic Bacillus coagulans GBI-30, 6086 (BC30) has been shown to increase protein digestion in an vitro model of the stomach and small intestine. Once active intestine after germination, BC30 aids carbohydrates proteins. The extent which administration may impact amino acid appearance humans ingestion is currently unknown. This study examined adding a 25-g dose milk concentrate on post-prandial changes blood acids concentrations. Methods 14 males 16 females (n = 30, 26.4 ± 6.5 years; 172.3 10.8 cm; 78.2 14.8 kg; 22.6 7.2% fat) completed two supplementation protocols that each spanned weeks separated by washout period lasted three weeks. Participants were instructed track their dietary intake ingest daily with (MPCBC30) or without (MPC) addition BC30. Body composition demographics assessed upon arrival laboratory. Upon final assigned supplemental dose, samples taken at 0 (baseline), 60, 90, 120, 180, 240 min post-consumption analyzed for Results Arginine ( p 0.03) Isoleucine 0.05) revealed greater area-under-the curve (AUC) MPCBC30 group compared MPC. In addition, 0.02), Serine 0.01), Ornithine Methionine 0.04), Glutamic Acid Phenylalanine 0.05), Tyrosine Essential Amino Acids Total < 0.01) all significantly concentration maximum (C Max ) Finally, time reach C (T was faster Glutamine Citrulline Threonine Alanine 0.02) when Greater mean differences between groups AUC women men found several acids. Conclusion concert previous evidence improved appearance, these results reveal sources such as can improve AUC, , T . Follow-up research should examine gender explore how aging outcomes. Retrospectively registered June 11, 2020 ClinicalTrials.gov NCT04427020.

Language: Английский

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