Biosynthesis, characterization, and investigation of cytotoxic activities of selenium nanoparticles utilizing Limosilactobacillus fermentum DOI Creative Commons

Seyed Amirhamzeh Aminisough,

Sara Daneshjou, Khosro Khajeh

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract The biosynthesis of selenium nanoparticles (SeNPs) is one the methods used alongside other conventional for SeNP synthesis. In this research, we cell-free culture (CFC) Limosilactobacillus fermentum We investigated SeNPs under various levels temperature, pH, and Se 4+ concentration characterized biosynthesized using FE-SEM, energy-dispersive X-ray, Fourier transform infrared spectroscopy, X-ray diffraction, ultraviolet–visible spectroscopy (UV–Vis), dynamic light scattering–zeta potential analyses to find with desirable properties. Also, cellular toxicity against MCF-7 cell line was analyzed. scavenging activity free radicals in CFC before after synthesis examined DPPH method. selected has an average hydrodynamic radius 92.52 nm a polydispersity index 0.134. This nanoparticle also mostly spherical shape, amorphous nature, zeta −32.2 mV. much lower than sodium selenite salt. It confirmed that during synthesis, reducing ability significantly decreases. research aimed design safe, cheap, eco-friendly protocol . As result, possess great further exploration realm biomedicine.

Language: Английский

“Revolutionizing Cancer Treatment: The Role of Starch‐Based Nanoparticles in Targeted Therapy” DOI Open Access
Devesh U. Kapoor,

Geeta Patel,

Bhupendra G. Prajapati

et al.

Starch - Stärke, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

ABSTRACT The biocompatible and biodegradable polysaccharide starch is a great platform for the development of nanoparticles (NPs). Due to its special qualities, which include high stability, low toxicity, ease modification, it desirable option administration anticancer drugs. Targeted cancer therapy has found potential carrier in starch‐based (SNPs). SNPs can be functionalized with ligands target cells particular. These allow targeted medication delivery by identifying overexpressed receptors on tumor surfaces. have been studied relation chemotherapeutics, siRNAs, photothermal treatments, among other agents. They are also used combination therapy, where their combined targeting improves treatment outcomes. being evaluated number clinical trials. trials evaluate patient outcomes, safety, efficacy offer important information future uses. Regulatory bodies closely monitor various treatments based NPs. Clinical translation requires an understanding safety profiles, biodistribution, clearance mechanisms. In this review, we examine enhance through drug targeting.

Language: Английский

Citations

0
Investigation of dielectric properties of starch nanoparticles derived from arrowroot (Maranta arundinaceae L.) rhizomes DOI Creative Commons

Mummadireddy Ramya,

Rajita Ramanarayanan,

S. Esakki Muthu

et al.

Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102348 - 102348

Published: May 1, 2025

Language: Английский

Citations

0
Synthesis, characterization, and applications of starch-based nano drug delivery systems for breast cancer therapy: A review DOI

Shijuan Mei,

R. Roopashree,

Farag M. A. Altalbawy

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 280, P. 136058 - 136058

Published: Sept. 26, 2024

Language: Английский

Citations

3
Biosynthesis, characterization, and investigation of cytotoxic activities of selenium nanoparticles utilizing Limosilactobacillus fermentum DOI Creative Commons

Seyed Amirhamzeh Aminisough,

Sara Daneshjou, Khosro Khajeh

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract The biosynthesis of selenium nanoparticles (SeNPs) is one the methods used alongside other conventional for SeNP synthesis. In this research, we cell-free culture (CFC) Limosilactobacillus fermentum We investigated SeNPs under various levels temperature, pH, and Se 4+ concentration characterized biosynthesized using FE-SEM, energy-dispersive X-ray, Fourier transform infrared spectroscopy, X-ray diffraction, ultraviolet–visible spectroscopy (UV–Vis), dynamic light scattering–zeta potential analyses to find with desirable properties. Also, cellular toxicity against MCF-7 cell line was analyzed. scavenging activity free radicals in CFC before after synthesis examined DPPH method. selected has an average hydrodynamic radius 92.52 nm a polydispersity index 0.134. This nanoparticle also mostly spherical shape, amorphous nature, zeta −32.2 mV. much lower than sodium selenite salt. It confirmed that during synthesis, reducing ability significantly decreases. research aimed design safe, cheap, eco-friendly protocol . As result, possess great further exploration realm biomedicine.

Language: Английский

Citations

0